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Roanoke Regional Airport to St. Louis Lambert International Airport flight

Explore the cheapest one-way and round-trip flights from Roanoke Regional Airport to St. Louis Lambert International Airport over the next 90 days, with one-way fares from US$273 and round-trip from US$308. Based on Trip.com's latest 7-day flight data.

      • ROA 18:54
        6h 2m
        1 stop
        STL 23:56
        Roanoke - St. Louis | Thu, Nov 12 | Delta Air Lines
        STL 10:00
        3h 49m
        1 stop
        ROA 14:49
        St. Louis - Roanoke | Mon, Nov 16 | Delta Air Lines
        US$308 US$466
        34% off
        34% off
        US$466 US$308
      • ROA 16:49
        5h 8m
        1 stop
        STL 20:57
        Roanoke - St. Louis | Thu, Oct 29 | American Airlines
        STL 06:47
        4h 56m
        1 stop
        ROA 12:43
        St. Louis - Roanoke | Sun, Nov 1 | American Airlines
        US$320 US$466
        31% off
        31% off
        US$466 US$320
      • ROA 18:02
        6h 56m
        1 stop
        STL 23:58
        Roanoke - St. Louis | Thu, Nov 12 | American Airlines
        STL 13:58
        3h 55m
        1 stop
        ROA 18:53
        St. Louis - Roanoke | Mon, Nov 16 | American Airlines
        US$320 US$466
        31% off
        31% off
        US$466 US$320
      • ROA 18:38
        6h 16m
        1 stop
        STL 23:54
        Roanoke - St. Louis | Fri, Oct 30 | Delta Air Lines
        STL 14:25
        6h 32m
        1 stop
        ROA 21:57
        St. Louis - Roanoke | Sun, Nov 1 | Delta Air Lines
        US$329
        28% off
        US$466 US$329
      • ROA 18:59
        5h 55m
        1 stop
        STL 23:54
        Roanoke - St. Louis | Fri, Oct 9 | Delta Air Lines
        STL 19:20
        4h 7m
        1 stop
        ROA 00:27
        St. Louis - Roanoke | Thu, Oct 15 | Delta Air Lines
        US$331
        28% off
        US$466 US$331
      • ROA 16:12
        4h 6m
        1 stop
        STL 19:18
        Roanoke - St. Louis | Wed, Oct 28 | American Airlines
        STL 07:16
        4h 17m
        1 stop
        ROA 12:33
        St. Louis - Roanoke | Sat, Oct 31 | American Airlines
        US$339
        27% off
        US$466 US$339
      • ROA 16:49
        5h 8m
        1 stop
        STL 20:57
        Roanoke - St. Louis | Thu, Oct 22 | American Airlines
        STL 05:00
        4h 29m
        1 stop
        ROA 10:29
        St. Louis - Roanoke | Sun, Oct 25 | American Airlines
        US$340
        27% off
        US$466 US$340
      • ROA 05:07
        4h 30m
        1 stop
        STL 08:37
        Roanoke - St. Louis | Fri, Oct 23 | American Airlines
        STL 05:00
        4h 29m
        1 stop
        ROA 10:29
        St. Louis - Roanoke | Sun, Oct 25 | American Airlines
        US$340
        27% off
        US$466 US$340
      • ROA 06:00
        6h 15m
        1 stop
        STL 11:15
        Roanoke - St. Louis | Fri, Nov 20 | Delta Air Lines
        STL 15:30
        5h 25m
        1 stop
        ROA 21:55
        St. Louis - Roanoke | Sat, Nov 21 | Delta Air Lines
        US$348
        25% off
        US$466 US$348
      • ROA 18:38
        6h 16m
        1 stop
        STL 23:54
        Roanoke - St. Louis | Wed, Oct 28 | Delta Air Lines
        STL 07:00
        4h 33m
        1 stop
        ROA 12:33
        St. Louis - Roanoke | Sat, Oct 31 | Delta Air Lines
        US$348
        25% off
        US$466 US$348
      • ROA 18:54
        6h 2m
        1 stop
        STL 23:56
        Roanoke - St. Louis | Fri, Nov 13 | Delta Air Lines
        STL 10:05
        3h 43m
        1 stop
        ROA 14:48
        St. Louis - Roanoke | Tue, Nov 17 | Delta Air Lines
        US$348
        25% off
        US$466 US$348
      • ROA 05:07
        4h 30m
        1 stop
        STL 08:37
        Roanoke - St. Louis | Sat, Oct 17 | American Airlines
        STL 09:27
        4h 14m
        1 stop
        ROA 14:41
        St. Louis - Roanoke | Sat, Oct 24 | American Airlines
        US$354
        24% off
        US$466 US$354
      • ROA 13:00
        17h 25m
        1 stop
        STL 14:00
        Roanoke - St. Louis | Wed, Oct 7 | Normal Airline
        STL 15:00
        6h
        Nonstop
        ROA 16:00
        St. Louis - Roanoke | Fri, Oct 9 | Normal Airline
        More cheap flights
        More cheap flights
      • ROA 15:32
        6h 51m
        1 stop
        STL 21:23
        Roanoke - St. Louis | Fri, Oct 9 | Delta Air Lines
        US$273 US$407
        33% off
        33% off
        US$407 US$273
      • ROA 18:10
        6h 49m
        1 stop
        STL 23:59
        Roanoke - St. Louis | Fri, Oct 9 | American Airlines
        US$274 US$407
        33% off
        33% off
        US$407 US$274
      • ROA 05:07
        4h 30m
        1 stop
        STL 08:37
        Roanoke - St. Louis | Mon, Oct 19 | American Airlines
        US$275 US$407
        32% off
        32% off
        US$407 US$275
      • ROA 18:38
        24h 37m
        1 stop
        STL 18:15
        Roanoke - St. Louis | Mon, Oct 19 | Delta Air Lines
        US$280
        31% off
        US$407 US$280
      • ROA 17:51
        4h 49m
        1 stop
        STL 21:40
        Roanoke - St. Louis | Mon, Nov 2 | United Airlines
        US$282
        31% off
        US$407 US$282
      • ROA 06:30
        6h 40m
        1 stop
        STL 12:10
        Roanoke - St. Louis | Sun, Oct 25 | United Airlines
        US$282
        31% off
        US$407 US$282
      • ROA 06:00
        4h 9m
        1 stop
        STL 09:09
        Roanoke - St. Louis | Sun, Oct 25 | Delta Air Lines
        US$283
        30% off
        US$407 US$283
      • ROA 16:10
        6h 47m
        1 stop
        STL 21:57
        Roanoke - St. Louis | Mon, Nov 2 | American Airlines
        US$284
        30% off
        US$407 US$284
      • ROA 06:00
        6h 15m
        1 stop
        STL 11:15
        Roanoke - St. Louis | Tue, Nov 24 | Delta Air Lines
        US$284
        30% off
        US$407 US$284
      • ROA 16:49
        5h 8m
        1 stop
        STL 20:57
        Roanoke - St. Louis | Sun, Oct 11 | American Airlines
        US$287
        28% off
        US$407 US$287
      • ROA 05:07
        4h 30m
        1 stop
        STL 08:37
        Roanoke - St. Louis | Sun, Oct 25 | American Airlines
        US$288
        28% off
        US$407 US$288
      • ROA 06:49
        6h 26m
        1 stop
        STL 12:15
        Roanoke - St. Louis | Sun, Oct 11 | United Airlines
        US$309
        24% off
        US$407 US$309
      • ROA 13:00
        17h 25m
        1 stop
        STL 14:00
        Roanoke - St. Louis | Wed, Oct 7 | Normal Airline
        More cheap flights
        More cheap flights

Displayed flight fares from Roanoke Regional Airport to St. Louis Lambert International Airport are based on average prices across airlines for the next 3 months, according to the latest Trip.com database.

Which airline offers the cheapest flights from Roanoke Regional Airport to St. Louis Lambert International Airport?

The cheapest airline flying from Roanoke Regional Airport to St. Louis Lambert International Airport is Delta Air Lines (from US$273) among 3 carriers operating this route. Based on Trip.com's latest 7-day flight data.

Delta Air Lines
From US$273
American Airlines
From US$274
United Airlines
From US$282

Find more flights and airlines

What is the flight schedule from Roanoke Regional Airport to St. Louis Lambert International Airport?

Check on the flight schedule from Roanoke to St. Louis to find the flight that matches your travel plan.

Flight info.
Departure
Arrival
Weekly Schedule

  1. AA6050

    Roanoke Regional Airport

    14:17

    ROA

    1h 22m

    Nonstop

    15:39

    CLT

    S M T W T F S
    Search

  2. AA2686

    Charlotte Douglas International Airport

    18:51

    CLT

    1h 57m

    Nonstop

    19:48

    STL

    S M T W T F S

  3. DL2818

    Roanoke Regional Airport

    06:00

    ROA

    1h 40m

    Nonstop

    07:40

    ATL

    S M T W T F S
    Search

  4. DL1571

    Hartsfield–Jackson Atlanta International Airport

    08:25

    ATL

    1h 44m

    Nonstop

    09:09

    STL

    S M T W T F S

  5. AA5826

    Roanoke Regional Airport

    05:10

    ROA

    1h 23m

    Nonstop

    06:33

    CLT

    S - T W T F S
    Search

  6. AA2497

    Charlotte Douglas International Airport

    07:33

    CLT

    1h 57m

    Nonstop

    08:30

    STL

    S M T W T F S

  7. UA5350

    Roanoke Regional Airport

    17:38

    ROA

    1h 59m

    Nonstop

    18:37

    ORD

    S M T W T F S
    Search

  8. UA1625

    O'Hare International Airport

    19:50

    ORD

    1h 31m

    Nonstop

    21:21

    STL

    S M T W T F S

  9. UA5500

    Roanoke Regional Airport

    06:49

    ROA

    2h 11m

    Nonstop

    08:00

    ORD

    S M T W T F S
    Search

  10. UA4613

    O'Hare International Airport

    08:55

    ORD

    1h 40m

    Nonstop

    10:35

    STL

    S - T W T F S

  11. AA4190

    Roanoke Regional Airport

    16:49

    ROA

    2h 26m

    Nonstop

    18:15

    ORD

    S M T W T F S
    Search

  12. AA2444

    O'Hare International Airport

    19:18

    ORD

    1h 26m

    Nonstop

    20:44

    STL

    S M T W T F S

  13. AA5051

    Roanoke Regional Airport

    14:04

    ROA

    1h 19m

    Nonstop

    15:23

    CLT

    S M T W T F S
    Search

  14. AA2686

    Charlotte Douglas International Airport

    18:51

    CLT

    1h 57m

    Nonstop

    19:48

    STL

    S M T W T F S

  15. UA5350

    Roanoke Regional Airport

    17:38

    ROA

    1h 59m

    Nonstop

    18:37

    ORD

    S M T W T F S
    Search

  16. UA4576

    O'Hare International Airport

    21:30

    ORD

    1h 29m

    Nonstop

    22:59

    STL

    S - T W T F S

  17. DL2818

    Roanoke Regional Airport

    06:00

    ROA

    1h 40m

    Nonstop

    07:40

    ATL

    S M T W T F S
    Search

  18. DL1400

    Hartsfield–Jackson Atlanta International Airport

    10:05

    ATL

    1h 46m

    Nonstop

    10:51

    STL

    S M T W T F S

  19. DL4920

    Roanoke Regional Airport

    18:38

    ROA

    1h 36m

    Nonstop

    20:14

    ATL

    - M T W T - S
    Search

  20. DL1403

    Hartsfield–Jackson Atlanta International Airport

    22:55

    ATL

    1h 44m

    Nonstop

    23:39

    STL

    S M T W T F S
Find more flights and airlines

About Roanoke Regional Airport and St. Louis Lambert International Airport

Learn about Roanoke Regional Airport (ROA) and St. Louis Lambert International Airport (STL) — including location, terminals, transportation, and travel tips.

Flight distance 924.62 km
Cheapest one-way ticket price US$273
Cheapest return ticket price US$308

FAQs for Roanoke Regional Airport to St. Louis Lambert International Airport Flights

  • How many daily flights are there from Roanoke Regional Airport (ROA) to St. Louis Lambert International Airport (STL)?

    There are around 1 daily flights from Roanoke Regional Airport (ROA) to St. Louis Lambert International Airport (STL).
  • The route from Roanoke Regional Airport (ROA) to St. Louis Lambert International Airport (STL) is quite popular. Without considering departure times or holidays, tickets cost around US$697 in April, the most expensive month to book this route.
    • The distance from St. Louis Lambert International Airport to downtown is about 20 km, by taxi about 40 minutes.
  • One-way flights from Roanoke Regional Airport to St. Louis Lambert International Airport currently start from US$273, and round-trip fares start from US$308. The current lowest fare is a Delta Air Lines flight departing on Fri, Oct 9; prices may vary depending on availability.
  • Based on Trip.com flight data for departures within the next 30 days with at most one stop, the average one-way price from Roanoke Regional Airport to St. Louis Lambert International Airport is US$300. Prices may vary depending on the departure date, airline, and availability.
  • Enter Roanoke Regional Airport and St. Louis Lambert International Airport, select your departure date and number of passengers, then compare flights by price, flight duration, and baggage allowance. Once you've chosen a fare, review the change and refund rules, fill in passenger details, and pay to receive your booking confirmation.

Popular Destinations

Note: Prices shown on this page are the estimated lowest prices found in the last 24 hours and include all taxes and fees.

Book with no extra fees

Prices displayed on this page are all-inclusive (incl. taxes, fuel surcharges, Civil Aviation Development Fund, etc.), and all fees are clearly shown before you pay. Charges for checked baggage, onboard meals, Wi‑Fi, and other optional services are also included where applicable in the flight cards.

Real-time pricing updates

Prices, availability, and travel details on this page have been updated within the last 24 hours, and for many routes are refreshed in real time. The more popular the route, the more accurate and up-to-date the data.

Change & Cancellation Policy

Trip.com shows the change and cancellation rules for each ticket during the booking process, including all related fees and conditions. Please refer to the following scenarios:
Voluntary cancellation/change:
To request a change or cancellation, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and flight segment, and submit your request. Please note that additional charges may apply based on the airline’s fare rules.
Cancellation/change due to a flight schedule change:
If your flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For full details of change and cancellation policies, please refer to the customer support pages.