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Flights from Cali to Antofagasta

Cheapest airlines flights from Cali to Antofagasta

Fly from Cali to Antofagasta with 1 carriers, including JetSMART Airlines, JetSMART Airlines offers the cheapest flights from Cali to Antofagasta.
JetSMART Airlines logo JetSMART Airlines

Non stop flights available! Find direct flights from Cali to Antofagasta for the next 3 months. Book one way flights from US$147 or round trip tickets from US$343.

      • Cheapest nonstop
        CLO 13:09
        4h 27m
        Nonstop
        ANF 19:36
        Cali - Antofagasta | Tue, Dec 2 | JetSMART Airlines
        ANF 09:30
        4h 35m
        Nonstop
        CLO 12:05
        Antofagasta - Cali | Thu, Dec 4 | JetSMART Airlines
        US$343 US$387
        11% OFF
        11% OFF
        US$387 US$343
      • CLO 13:11
        4h 27m
        Nonstop
        ANF 19:38
        Cali - Antofagasta | Sat, Nov 29 | JetSMART Airlines
        ANF 09:30
        4h 35m
        Nonstop
        CLO 12:05
        Antofagasta - Cali | Sat, Dec 6 | JetSMART Airlines
        US$354 US$387
        9% OFF
        9% OFF
        US$387 US$354
      • CLO 13:11
        4h 27m
        Nonstop
        ANF 19:38
        Cali - Antofagasta | Mon, Nov 24 | JetSMART Airlines
        ANF 10:03
        11h 32m
        1 stop
        CLO 19:35
        Antofagasta - Cali | Tue, Dec 2 | JetSMART Airlines
        US$270 US$387
        30% OFF
        30% OFF
        US$387 US$270
      • CLO 13:09
        4h 27m
        Nonstop
        ANF 19:36
        Cali - Antofagasta | Mon, Dec 1 | JetSMART Airlines
        ANF 10:03
        11h 32m
        1 stop
        CLO 19:35
        Antofagasta - Cali | Tue, Dec 2 | JetSMART Airlines
        US$270
        30% OFF
        US$387 US$270
      • CLO 13:11
        4h 27m
        Nonstop
        ANF 19:38
        Cali - Antofagasta | Thu, Nov 20 | JetSMART Airlines
        ANF 23:43
        21h 48m
        1 stop
        CLO 19:31
        Antofagasta - Cali | Sat, Nov 22 | JetSMART Airlines
        US$282
        27% OFF
        US$387 US$282
      • CLO 13:11
        4h 27m
        Nonstop
        ANF 19:38
        Cali - Antofagasta | Fri, Dec 26 | JetSMART Airlines
        ANF 06:57
        14h 38m
        1 stop
        CLO 19:35
        Antofagasta - Cali | Thu, Jan 1 | JetSMART Airlines
        US$303
        22% OFF
        US$387 US$303
      • CLO 20:35
        31h 32m
        1 stop
        ANF 06:07
        Cali - Antofagasta | Wed, Nov 19 | JetSMART Airlines
        ANF 23:43
        21h 48m
        1 stop
        CLO 19:31
        Antofagasta - Cali | Sat, Nov 22 | JetSMART Airlines
        US$335
        13% OFF
        US$387 US$335
      • CLO 11:30
        18h 46m
        1 stop
        ANF 08:16
        Cali - Antofagasta | Wed, Jan 14 | JetSMART Airlines
        ANF 09:26
        12h 9m
        1 stop
        CLO 19:35
        Antofagasta - Cali | Wed, Jan 21 | JetSMART Airlines
        US$343
        11% OFF
        US$387 US$343
      • CLO 13:09
        4h 27m
        Nonstop
        ANF 19:36
        Cali - Antofagasta | Thu, Dec 4 | JetSMART Airlines
        ANF 07:12
        14h 23m
        1 stop
        CLO 19:35
        Antofagasta - Cali | Fri, Dec 12 | JetSMART Airlines
        US$357
        8% OFF
        US$387 US$357
      • CLO 13:09
        4h 27m
        Nonstop
        ANF 19:36
        Cali - Antofagasta | Thu, Dec 25 | JetSMART Airlines
        ANF 23:51
        22h 48m
        1 stop
        CLO 20:39
        Antofagasta - Cali | Wed, Dec 31 | JetSMART Airlines
        US$364
        6% OFF
        US$387 US$364
      • CLO 13:00
        17h 25m
        1 stop
        ANF Invalid Date
        Cali - Antofagasta | Fri, Nov 21 | Normal Airline
        ANF 15:00
        6h
        Nonstop
        CLO 16:00
        Antofagasta - Cali | Sun, Nov 23 | Normal Airline
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Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Cali to Antofagasta Flight Information

The distance between Cali and Antofagasta is approximately 3,069.13 km. On average, a flight from Cali to Antofagasta takes around 4 hours 27 minutes. The most popular month to fly to Antofagasta is July. The off-season for travel is September.

Cheapest one-way flight priceUS$147
Cheapest return ticket priceUS$270
Cheapest monthSeptember
Peak season for travelJuly
Flight distance3,069.13 km
Average flight time4 hours 27 minutes
Popular airlineJetSMART

When is the cheapest time to book flights from Cali to Antofagasta?

Best time for cheap flights from Cali to Antofagasta are between Dec 21 and Dec 28 with one way fares from US$147

Cheapest flights
From price
Search
  • 1623
  • 2330

  • Dec

    307
  • 714
  • 1421
  • 2128

  • Jan

    284
  • 411
  • 1118
  • 1825

  • Feb

    251
  • 18
Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Frequently Asked Questions

  • Which airlines offer direct flights from Cali to Antofagasta?

    At the moment, you can catch a nonstop flight from Cali to Antofagasta with the following airlines, including: JetSMART Selected airlines are based on historical data collected from flight bookings users made on Trip.com within the last 90 days.
  • It takes about 4 hours 27 minutes to fly from Cali to Antofagasta.
  • By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Cali to Antofagasta is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.
  • Based on Trip.com data in the past 4 weeks, there is 3 flight per week flying from Cali to Antofagasta. You can check the weekly schedule for popular airlines on this route below: JetSMART: -/-/-/-/-/-/- -- JA1091 (14:29) JetSMART: S/M/-/W/-/F/- -- JA811 (13:13)
  • The cheapest months to fly from Cali to Antofagasta is September, when demand for travel is lower.
  • After crunching the numbers on our November flight calendar, it's currently cheapest to fly from Cali to Antofagasta on November 22, 2025 with JetSMART, with prices starting at US$147.
  • You can land at any one of the following hubs in Antofagasta, with Alfonso Bonilla Aragon International Airport to Andres Sabella Airport (CLO-ANF) is by far the most common option on this route: Andres Sabella Airport (ANF).
  • The time difference between Antofagasta and Cali is 1h.
  • Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.

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