Cheapest airlines flights from Charlotte to Panama City

You can choose from 1 airlines that fly from Charlotte to Panama City, including American Airlines, American Airlines has lowest fares on this route.
American Airlines logo American Airlines
Airlines are determined based on actual purchased flight tickets from Charlotte to Panama City according to previous 12 months data from Trip.com.

Search for direct flights from Charlotte to Panama City in the next 3 months. Based on Trip.com's latest 7-day flight data, one-way direct flights start at US$387, and round-trip direct flights start at US$237.

Displayed flight fares from Charlotte to Panama City are based on average prices across airlines for the next 3 months, according to the latest Trip.com database.

Charlotte to Panama City Flight Details

The distance between Charlotte and Panama City is about 713.56 km. The average flying time from Charlotte to Panama City is around 1 hour 53 minutes. Based on Trip.com's latest data, travel demand is highest in July. The off-season for travel is September.

Cheapest one-way flight priceUS$151
Cheapest return ticket priceUS$234
Cheapest monthSeptember
Peak season for travelJuly
Flight distance713.56 km
Average flight time1 hour 53 minutes
Popular airlineAmerican Airlines
Flight statistics for the Charlotte–Panama City route are based on aggregated booking data from Trip.com over the past 12 months.

Frequently Asked Questions

  • What are the cheapest flights from Charlotte to Panama City (CLT-ECP)?

    Based on Trip.com data, American Airlines offers one-way fares as low as US$151 on Cheapest nonstop routes (e.g. CLT to ECP on Fri, Mar 6), while Delta Air Lines offers Cheapest nonstop round-trips from US$234 departing on Sat, Feb 28 and returning on Sat, Mar 7.
  • At the moment, you can catch a nonstop flight from Charlotte to Panama City with the following airlines, including: American Airlines Selected airlines are based on historical data collected from flight bookings users made on Trip.com within the last 90 days.
  • It takes about 1 hour 53 minutes to fly from Charlotte to Panama City.
  • By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Charlotte to Panama City is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.
  • Based on Trip.com data in the past 4 weeks, there is 19 flight per week flying from Charlotte to Panama City. You can check the weekly schedule for popular airlines on this route below: American Airlines: S/M/T/W/T/F/S -- AA5075 (12:52) American Airlines: S/M/T/W/T/F/S -- AA5161 (09:14) American Airlines: S/M/T/W/T/F/S -- AA5277 (21:49)
  • To find best deals on flights from Charlotte to Panama City, you can use various tools on Trip.com:
    · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Fri, Mar 6, with one-way flights priced at just US$151.
    · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is American Airlines.
    · Set up price alerts to easily monitor ticket prices without having to check every day.
    · Check Trip.com flight deals and promo codes frequently.
    · Avoid peak season unless you book very early. It seems the peak season for Panama City travel is around July.
    · Get exclusive promo codes for Trip.com app users.
  • The cheapest months to fly from Charlotte to Panama City is September, when demand for travel is lower.
  • After crunching the numbers on our February flight calendar, it's currently cheapest to fly from Charlotte to Panama City on February 20, 2026 with Delta Air Lines, with prices starting at US$234.
  • You can land at any one of the following hubs in Panama City, with Charlotte Douglas International Airport to Northwest Florida Beaches International Airport (CLT-ECP) is by far the most common option on this route: Northwest Florida Beaches International Airport (ECP).
  • The time difference between Panama City and Charlotte is 1h.
  • Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.

Trip.com Airline Insights on Flights from Charlotte to Panama City

How many flights fly from Charlotte to Panama City daily?

The data is based on the flight numbers for each day of the week from Charlotte to Panama City within the Trip.com database over the past month.

Based on the past month's historical data from Trip.com, the number of flights from Charlotte to Panama City is the highest on Friday and the lowest on Tuesday.

11
9
6
4
Highest
7
Mon
6
Tue
8
Wed
8
Thu
11
Fri
10
Sat
7
Sun