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Chile to Panama flight

Flying From Chile to Panama: What You Need to Know

Cheapest one-way flight priceUS$223
Cheapest return ticket priceUS$480
Cheapest monthNovember
Peak season for travelJuly
Popular airlineCopa Airlines

Compare multiple airlines at once to find the best flight deals from Chile to Panama.

Airlines Flying From Chile to Panama
Copa Airlines logo Copa Airlines
avianca logo avianca

Search Flights From Chile to Panama

Easily compare flights from Chile to Panama and find the cheapest tickets available!

Looking for affordable flights from Chile to Panama? Check out these great prices for the next 90 days, starting at just US$223 for a one-way ticket and US$480 for a round-trip.

      • Cheapest nonstop
        Wed, Apr 15
        SCL
        PTY
        |
        Santiago
        Panama City
        Nonstop | Copa Airlines
        Sun, Apr 19
        PTY
        SCL
        |
        Panama City
        Santiago
        Nonstop | Copa Airlines
        US$498 US$1,340
        63% off
        63% off
        US$1,340 US$498
      • Wed, Apr 15
        SCL
        PTY
        |
        Santiago
        Panama City
        1 stop | avianca
        Sun, Apr 19
        PTY
        SCL
        |
        Panama City
        Santiago
        1 stop | avianca
        US$480 US$1,340
        64% off
        64% off
        US$1,340 US$480
      • Wed, May 20
        SCL
        BOC
        |
        Santiago
        Bocas Del Toro
        1 stop | Copa Airlines
        Sun, May 24
        BOC
        SCL
        |
        Bocas Del Toro
        Santiago
        1 stop | Euroairlines
        US$1,219 US$1,340
        9% off
        9% off
        US$1,340 US$1,219
      • Tue, Apr 14
        SCL
        PTY
        |
        Santiago
        Panama City
        1 stop | Normal Airline
        Thu, Apr 16
        PTY
        SCL
        |
        Panama City
        Santiago
        Nonstop | Normal Airline
        Find more flights
        Find more flights
      • Cheapest nonstop
        Thu, Apr 23
        SCL
        PTY
        |
        Santiago
        Panama City
        Nonstop | Copa Airlines
        US$893 US$1,283
        30% off
        30% off
        US$1,283 US$893
      • Sun, Apr 26
        SCL
        PTY
        |
        Santiago
        Panama City
        1 stop | avianca
        US$223 US$1,283
        83% off
        83% off
        US$1,283 US$223
      • Fri, May 15
        SCL
        DAV
        |
        Santiago
        David
        1 stop | Copa Airlines
        US$930 US$1,283
        28% off
        28% off
        US$1,283 US$930
      • Wed, May 6
        CCP
        PTY
        |
        Concepcion
        Panama City
        1 stop | Sky Airline
        US$977
        24% off
        US$1,283 US$977
      • Thu, Apr 30
        CPO
        PTY
        |
        Copiapo
        Panama City
        1 stop | Sky Airline
        US$1,006
        22% off
        US$1,283 US$1,006
      • Sat, Apr 18
        SCL
        OTD
        |
        Santiago
        Contadora
        1 stop | Copa Airlines
        US$1,058
        18% off
        US$1,283 US$1,058
      • Sat, May 9
        CJC
        PTY
        |
        Calama
        Panama City
        1 stop | Sky Airline
        US$1,106
        14% off
        US$1,283 US$1,106
      • Fri, Jun 5
        SCL
        BOC
        |
        Santiago
        Bocas Del Toro
        1 stop | Copa Airlines
        US$1,167
        9% off
        US$1,283 US$1,167
      • Tue, Apr 14
        SCL
        PTY
        |
        Santiago
        Panama City
        1 stop | Normal Airline
        Find more flights
        Find more flights

Displayed flight fares from Santiago to Panama City are based on average prices across airlines for the next 3 months, according to the latest Trip.com database.

FAQs: Flights From Chile to Panama

  • When is it the cheapest time to fly from Chile to Panama?

    According to our flights calender over the next 90 days, the cheapest date is on 2026-04-25 for one-way flights.
  • The cheapest round-trip flight from Chile to Panama is on the route from Santiago and Panama City, with prices starting at US$480 for round trip between 2026-04-15 and 2026-04-19.
  • Based on our flight data, the average flight time from Chile to Panama is approximately 6 hours 44 minutes based on our most popular routes from Santiago to Panama City. The time may also vary depending on your destinations.
  • The cheapest airline flying to Panama from Chile is avianca serving route from Santiago to Panama City.
  • avianca are airlines that fly frequently from Chile to Panama. The overall price will vary depending on your destination and travel dates.

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