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Dominican Republic to Panama flight

Flying From Dominican Republic to Panama: What You Need to Know

Cheapest one-way flight priceUS$197
Cheapest return ticket priceUS$402
Cheapest monthOctober
Peak season for travelJanuary
Popular airlineCopa Airlines

Compare multiple airlines at once to find the best flight deals from Dominican Republic to Panama.

Airlines Flying From Dominican Republic to Panama
Copa Airlines logo Copa Airlines

Search Flights From Dominican Republic to Panama

Easily compare flights from Dominican Republic to Panama and find the cheapest tickets available!

Looking for affordable flights from Dominican Republic to Panama? Check out these great prices for the next 90 days, starting at just US$197 for a one-way ticket and US$402 for a round-trip.

      • Cheapest nonstop
        Sat, Apr 25
        STI
        PTY
        |
        Santiago
        Panama City
        Nonstop | Copa Airlines
        Mon, Apr 27
        PTY
        STI
        |
        Panama City
        Santiago
        Nonstop | Copa Airlines
        US$450 US$873
        48% off
        48% off
        US$873 US$450
      • Tue, Apr 28
        POP
        PTY
        |
        Puerto Plata
        Panama City
        Nonstop | Copa Airlines
        Fri, May 1
        PTY
        POP
        |
        Panama City
        Puerto Plata
        Nonstop | Copa Airlines
        US$474 US$873
        46% off
        46% off
        US$873 US$474
      • Tue, Apr 28
        PUJ
        PTY
        |
        Punta Cana
        Panama City
        1 stop | avianca
        Tue, May 5
        PTY
        PUJ
        |
        Panama City
        Punta Cana
        1 stop | avianca
        US$402 US$873
        54% off
        54% off
        US$873 US$402
      • Sun, Apr 19
        SDQ
        PTY
        |
        Santo Domingo
        Panama City
        1 stop | avianca
        Sun, Apr 26
        PTY
        SDQ
        |
        Panama City
        Santo Domingo
        1 stop | avianca
        US$475
        46% off
        US$873 US$475
      • Mon, Jun 1
        PUJ
        DAV
        |
        Punta Cana
        David
        1 stop | Copa Airlines
        Mon, Jun 8
        DAV
        PUJ
        |
        David
        Punta Cana
        1 stop | Copa Airlines
        US$611
        30% off
        US$873 US$611
      • Mon, Apr 27
        SDQ
        DAV
        |
        Santo Domingo
        David
        1 stop | Copa Airlines
        Mon, May 4
        DAV
        SDQ
        |
        David
        Santo Domingo
        1 stop | Copa Airlines
        US$646
        26% off
        US$873 US$646
      • Sun, Apr 19
        PUJ
        PTY
        |
        Punta Cana
        Panama City
        1 stop | Normal Airline
        Tue, Apr 21
        PTY
        PUJ
        |
        Panama City
        Punta Cana
        Nonstop | Normal Airline
        Find more flights
        Find more flights
      • Cheapest nonstop
        Sat, Apr 18
        STI
        PTY
        |
        Santiago
        Panama City
        Nonstop | Copa Airlines
        US$530 US$1,191
        55% off
        55% off
        US$1,191 US$530
      • Sun, May 3
        POP
        PTY
        |
        Puerto Plata
        Panama City
        Nonstop | Copa Airlines
        US$532 US$1,191
        55% off
        55% off
        US$1,191 US$532
      • Thu, May 14
        PUJ
        PTY
        |
        Punta Cana
        Panama City
        1 stop | avianca
        US$197 US$1,191
        83% off
        83% off
        US$1,191 US$197
      • Tue, May 19
        SDQ
        PTY
        |
        Santo Domingo
        Panama City
        1 stop | DM Airlines
        US$225
        81% off
        US$1,191 US$225
      • Fri, Apr 24
        STI
        PTY
        |
        Santiago
        Panama City
        1 stop | Jetblue Airways
        US$359
        70% off
        US$1,191 US$359
      • Thu, May 14
        POP
        PTY
        |
        Puerto Plata
        Panama City
        1 stop | American Airlines
        US$467
        61% off
        US$1,191 US$467
      • Wed, Jun 10
        LRM
        PTY
        |
        La Romana
        Panama City
        1 stop | American Airlines
        US$562
        53% off
        US$1,191 US$562
      • Sun, May 10
        SDQ
        DAV
        |
        Santo Domingo
        David
        1 stop | Copa Airlines
        US$640
        46% off
        US$1,191 US$640
      • Sun, May 3
        PUJ
        DAV
        |
        Punta Cana
        David
        1 stop | Copa Airlines
        US$654
        45% off
        US$1,191 US$654
      • Mon, May 11
        POP
        DAV
        |
        Puerto Plata
        David
        1 stop | Copa Airlines
        US$664
        44% off
        US$1,191 US$664
      • Sat, May 23
        SDQ
        BOC
        |
        Santo Domingo
        Bocas Del Toro
        1 stop | Copa Airlines
        US$881
        26% off
        US$1,191 US$881
      • Sun, Apr 19
        PUJ
        PTY
        |
        Punta Cana
        Panama City
        1 stop | Normal Airline
        Find more flights
        Find more flights

Displayed flight fares from Punta Cana to Panama City are based on average prices across airlines for the next 3 months, according to the latest Trip.com database.

FAQs: Flights From Dominican Republic to Panama

  • When is it the cheapest time to fly from Dominican Republic to Panama?

    According to our flights calender over the next 90 days, the cheapest date is on 2026-05-08 for one-way flights.
  • The cheapest round-trip flight from Dominican Republic to Panama is on the route from Punta Cana and Panama City, with prices starting at US$402 for round trip between 2026-04-28 and 2026-05-05.
  • Based on our flight data, the average flight time from Dominican Republic to Panama is approximately 2 hours 45 minutes based on our most popular routes from Punta Cana to Panama City. The time may also vary depending on your destinations.
  • The cheapest airline flying to Panama from Dominican Republic is avianca serving route from Punta Cana to Panama City.
  • Copa Airlines are airlines that fly frequently from Dominican Republic to Panama. The overall price will vary depending on your destination and travel dates.

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