Cheapest airlines flights from Comayagua to Medellin

You can choose from 2 airlines that fly from Comayagua to Medellin, including Copa Airlines, avianca, avianca has lowest fares on this route.
Copa Airlines logo Copa Airlines
avianca logo avianca
Airlines are determined based on actual purchased flight tickets from Comayagua to Medellin according to previous 12 months data from Trip.com.

Search cheap flights from Comayagua to Medellin in the next 3 months. Based on Trip.com's latest 7-day data, one-way fares start at US$203, and round-trip tickets start at US$411.

Displayed flight fares from Comayagua to Medellin are based on average prices across airlines for the next 3 months, according to the latest Trip.com database.

Comayagua to Medellin Flight Details

The distance between Comayagua and Medellin is about 1,602.45 km. Based on Trip.com's latest data, travel demand is highest in July. The off-season for travel is October.

Cheapest one-way flight priceUS$203
Cheapest return ticket priceUS$411
Cheapest monthOctober
Peak season for travelJuly
Flight distance1,602.45 km
Popular airlineCopa Airlines
Flight statistics for the Comayagua–Medellin route are based on aggregated booking data from Trip.com over the past 12 months.

Frequently Asked Questions

  • What are the cheapest flights from Comayagua to Medellin (XPL-MDE)?

    Based on Trip.com data, avianca offers one-way fares as low as US$203 on Cheapest nonstop routes (e.g. XPL to MDE on Thu, Jun 11), while avianca offers Cheapest nonstop round-trips from US$411 departing on Fri, Jun 12 and returning on Sun, Jun 14.
  • At the moment, several airlines serve connecting flights from Comayagua to Medellin, including: Copa Airlines avianca Selected airlines are based on historical data collected from flight bookings made by users on Trip.com within the last 90 days.
  • By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Comayagua to Medellin is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.
  • To find best deals on flights from Comayagua to Medellin, you can use various tools on Trip.com:
    · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Thu, Jun 11, with one-way flights priced at just US$203.
    · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is avianca.
    · Set up price alerts to easily monitor ticket prices without having to check every day.
    · Check Trip.com flight deals and promo codes frequently.
    · Avoid peak season unless you book very early. It seems the peak season for Medellin travel is around July.
    · Get exclusive promo codes for Trip.com app users.
  • The cheapest months to fly from Comayagua to Medellin is October, when demand for travel is lower.
  • After crunching the numbers on our June flight calendar, it's currently cheapest to fly from Comayagua to Medellin on June 14, 2026 with avianca, with prices starting at US$365.
  • You can land at any one of the following hubs in Medellin, with Comayagua Airport to Jose Maria Cordova International Airport (XPL-MDE) is by far the most common option on this route: Olaya Herrera Airport (EOH) Jose Maria Cordova International Airport (MDE).
  • The time difference between Medellin and Comayagua is 1h.
  • Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.

Note: Prices shown on this page are the estimated lowest prices found in the last 24 hours and include all taxes and fees.

Book with no extra fees

Prices displayed on this page are all-inclusive (incl. taxes, fuel surcharges, Civil Aviation Development Fund, etc.), and all fees are clearly shown before you pay. Charges for checked baggage, onboard meals, Wi‑Fi, and other optional services are also included where applicable in the flight cards.

Real-time pricing updates

Prices, availability, and travel details on this page have been updated within the last 24 hours, and for many routes are refreshed in real time. The more popular the route, the more accurate and up-to-date the data.

Change & Cancellation Policy

Trip.com shows the change and cancellation rules for each ticket during the booking process, including all related fees and conditions. Please refer to the following scenarios:
Voluntary cancellation/change:
To request a change or cancellation, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and flight segment, and submit your request. Please note that additional charges may apply based on the airline’s fare rules.
Cancellation/change due to a flight schedule change:
If your flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For full details of change and cancellation policies, please refer to the customer support pages.