Worldwide Coverage
Worldwide Coverage
Flights to over 5,000 cities
One-stop Service Guarantee
One-stop Service Guarantee
Price guaranteed upon confirmed payment, booking guaranteed once tickets issued
Secure Payment
Secure Payment
Convenient & reliable booking and payment system

Denver to Santiago - Flights Starting at US$347

Book one-way or return flights from Denver to Santiago from as little as US$347. Choose from the popular airlines below and book your flight today!

  • One way
  • Round-trip

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

We've found these cheap flights for you. You may book a one-way or round trip as per your needs.

We monitor flight fares to help you seize the best deals effortlessly

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.
Cheapest airlines flights from Denver to Santiago

View airlines operating flights from Denver to Santiago. Compare prices, find the option that best suits your travel needs, and enjoy a comfortable journey with a trusted airline.

Frontier Airlines
From US$278
Delta Air Lines
From US$294
United Airlines
From US$295
Copa Airlines
From US$314
LATAM Airlines
From US$315
Aeromexico
From US$344
American Airlines
From US$396
Jetblue Airways
From US$415
Southwest Airlines
From US$520
Avianca
From US$532
ANA airlines

Find more flights and airlines

Alternative Routes from Denver to Santiago

Discover different routes, airlines, and transfers and find the best alternative flights for your journey from Denver to Santiago.

  • Cheapest
    Frontier Airlines
    DEN
    00:10
    26h 15m
    2 transfer
    SCL
    04:25
    Denver International Airport - Arturo Merino Benitez Airport
    Wed, May 1Frontier Airlines
    US$278
  • Frontier Airlines
    DEN
    00:10
    26h 15m
    2 transfer
    SCL
    04:25
    Denver International Airport - Arturo Merino Benitez Airport
    Wed, May 1Frontier Airlines
    US$278
    Find More Flights

Frequently Asked Questions

  • When are flight tickets from Denver (DEN) to Santiago (SCL) the cheapest?

    Airlines adjust prices for flights from Denver to Santiago based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.
  • How much do flights from Denver (DEN) to Santiago (SCL) cost?

    According to Trip.com's data, the lowest price is around $965.
  • What is the transportation method from the main airport to downtown in Santiago?

    • The distance from Arturo Merino Benitez Airport to downtown is about 12km. It takes about 30 minutes by taxi.

How to find a cheap flight from Denver to Santiago

Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Denver to Santiago. Book your flights at the right time and save more.
1
Book Early
Once prices are gone, they're gone. Lock in deals while you can!
2
Compare Flight Prices
Compare prices on travel agency and airline websites.
3
Look Out for Deals
Check airline and travel agency websites for latest flight deals
4
Check One-way Fares
Buying two cheap one-way flights can sometimes be a better deal than a round-trip.
5
Try Different Dates
Flying during the week, early in the morning, or late at night can help save money.
6
Use the Trip.com App
Save up to £10 per person when booking your flights on Trip.com
Denver to Santiago Flight Information

Cheapest nonstop flight price

$346

Off-season for travel

December

Peak season for travel

October

Flight distance

8,859.26km

Popular airline

American Airlines