Trip.com
>
Flights
>
Flights to Italy
>
Flights to Sicily
>
Flights to Comiso
Hotels in Comiso
>
Flights from Des Moines to Comiso

Search cheap flights from Des Moines to Comiso in the next 3 months. Based on Trip.com's latest 7-day data, one-way fares start at US$653, and round-trip tickets start at US$682.

      • DSM 08:00
        31h 15m
        2 stops
        CIY 22:15
        Des Moines - Comiso | Wed, Dec 10 | United Airlines
        CIY 18:50
        30h 15m
        2 stops
        DSM 18:05
        Comiso - Des Moines | Wed, Dec 17 | Aeroitalia Airlines
        US$682 US$1,716
        60% OFF
        60% OFF
        US$1,716 US$682
      • DSM 17:16
        45h 59m
        2 stops
        CIY 22:15
        Des Moines - Comiso | Wed, Jan 14 | KLM
        CIY 07:10
        22h 19m
        2 stops
        DSM 22:29
        Comiso - Des Moines | Wed, Jan 21 | Aeroitalia Airlines
        US$730 US$1,716
        56% OFF
        56% OFF
        US$1,716 US$730
      • DSM 06:17
        21h 28m
        2 stops
        CIY 10:45
        Des Moines - Comiso | Thu, Dec 11 | Delta Air Lines
        CIY 07:10
        20h 36m
        2 stops
        DSM 20:46
        Comiso - Des Moines | Thu, Dec 18 | Aeroitalia Airlines
        US$990 US$1,716
        42% OFF
        42% OFF
        US$1,716 US$990
      • DSM 05:34
        33h 41m
        2 stops
        CIY 22:15
        Des Moines - Comiso | Fri, Dec 12 | KLM
        CIY 07:10
        21h 51m
        2 stops
        DSM 22:01
        Comiso - Des Moines | Fri, Dec 19 | Aeroitalia Airlines
        US$993
        42% OFF
        US$1,716 US$993
      • DSM 11:26
        27h 49m
        2 stops
        CIY 22:15
        Des Moines - Comiso | Wed, Jan 14 | Air France
        CIY 07:10
        22h 19m
        2 stops
        DSM 22:29
        Comiso - Des Moines | Wed, Jan 21 | Aeroitalia Airlines
        US$1,012
        41% OFF
        US$1,716 US$1,012
      • DSM 15:00
        36h 45m
        2 stops
        CIY 10:45
        Des Moines - Comiso | Sat, Dec 13 | Delta Air Lines
        CIY 18:50
        34h 41m
        2 stops
        DSM 22:31
        Comiso - Des Moines | Sat, Dec 20 | Aeroitalia Airlines
        US$1,253
        27% OFF
        US$1,716 US$1,253
      • DSM 10:20
        17h 25m
        2 stops
        CIY 10:45
        Des Moines - Comiso | Tue, Dec 16 | Delta Air Lines
        CIY 07:10
        17h 38m
        2 stops
        DSM 17:48
        Comiso - Des Moines | Tue, Dec 23 | Aeroitalia Airlines
        US$1,343
        22% OFF
        US$1,716 US$1,343
      • DSM 10:20
        28h 55m
        2 stops
        CIY 22:15
        Des Moines - Comiso | Tue, Dec 16 | Air France
        CIY 07:10
        22h 21m
        2 stops
        DSM 22:31
        Comiso - Des Moines | Tue, Dec 23 | Aeroitalia Airlines
        US$1,452
        15% OFF
        US$1,716 US$1,452
      • DSM 10:20
        28h 55m
        2 stops
        CIY 22:15
        Des Moines - Comiso | Tue, Dec 16 | KLM
        CIY 07:10
        22h 21m
        2 stops
        DSM 22:31
        Comiso - Des Moines | Tue, Dec 23 | Aeroitalia Airlines
        US$1,452
        15% OFF
        US$1,716 US$1,452
      • DSM 12:04
        15h 41m
        2 stops
        CIY 10:45
        Des Moines - Comiso | Mon, Jan 5 | Delta Air Lines
        CIY 18:50
        34h 39m
        2 stops
        DSM 22:29
        Comiso - Des Moines | Mon, Jan 12 | Aeroitalia Airlines
        US$1,527
        11% OFF
        US$1,716 US$1,527
      • DSM 13:00
        17h 25m
        1 stop
        CIY Invalid Date
        Des Moines - Comiso | Fri, Dec 12 | Normal Airline
        CIY 15:00
        6h
        Nonstop
        DSM 16:00
        Comiso - Des Moines | Sun, Dec 14 | Normal Airline
        Find More Flights
        Find More Flights

Displayed flight fares from Des Moines to Comiso are based on average prices across airlines for the next 3 months, according to the latest Trip.com database.

Des Moines to Comiso Flight Details

The distance between Des Moines and Comiso is about 8,649.05 km. Based on Trip.com's latest data, travel demand is highest in November. The off-season for travel is December.

Cheapest one-way flight priceUS$653
Cheapest return ticket priceUS$682
Cheapest monthDecember
Peak season for travelNovember
Flight distance8,649.05 km

When is the cheapest time to book flights from Des Moines to Comiso?

The cheapest time to fly from Des Moines to Comiso: Dec 14 to Dec 21 — one-way prices start at US$653.

Cheapest flights
From price
Search
  • 714
  • 1421
  • 2128

  • Jan

    284
  • 411
  • 1118
  • 1825

  • Feb

    251
  • 18
  • 815
  • 1522

  • Mar

    221
Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Frequently Asked Questions

  • What are the cheapest flights from Des Moines to Comiso (DSM-CIY)?

    Based on Trip.com data, United Airlines offers one-way fares as low as US$653 on Cheapest nonstop routes (e.g. DSM to CIY on Mon, Dec 15), while United Airlines offers Cheapest nonstop round-trips from US$682 departing on Wed, Dec 10 and returning on Wed, Dec 17.
  • By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Des Moines to Comiso is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.
  • To find best deals on flights from Des Moines to Comiso, you can use various tools on Trip.com:
    · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Mon, Dec 15, with one-way flights priced at just US$653.
    · Set up price alerts to easily monitor ticket prices without having to check every day.
    · Check Trip.com flight deals and promo codes frequently.
    · Avoid peak season unless you book very early. It seems the peak season for Comiso travel is around November.
    · Get exclusive promo codes for Trip.com app users.
  • The cheapest months to fly from Des Moines to Comiso is December, when demand for travel is lower.
  • The time difference between Comiso and Des Moines is 7h.
  • Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.

Explore More Popular Flights