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Flights from Detroit to St. Louis
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Find cheap one-way flights from Detroit to St. Louis starting at US$103.
We've found these cheap flights for you. You can book one-way or round-trip flight tickets.
- One way
- Round-trip
- DTW05:006h 35m1 stopSTL10:35Wed, May 15|Detroit - St. Louis|Spirit AirlinesUS$103US$13825% OFF25% OFFUS$138US$103
- DTW12:369h 38m1 stopSTL21:14Tue, Apr 2|Detroit - St. Louis|Frontier AirlinesUS$105US$13824% OFF24% OFFUS$138US$105
- DTW18:3813h 35m1 stopSTL07:13Thu, Apr 11|Detroit - St. Louis|Frontier AirlinesUS$107US$13823% OFF23% OFFUS$138US$107
- DTW09:1012h 30m1 stopSTL20:40Sat, Apr 13|Detroit - St. Louis|Southwest AirlinesUS$108US$108
- DTW12:0521h 16m1 stopSTL08:21Wed, Apr 3|Detroit - St. Louis|Frontier AirlinesUS$110US$110
- DTW12:0021h 21m1 stopSTL08:21Mon, Apr 8|Detroit - St. Louis|Frontier AirlinesUS$111US$111
- DTW22:2310h 58m1 stopSTL08:21Thu, Apr 4|Detroit - St. Louis|Frontier AirlinesUS$111US$111
- DTW05:209h 17m1 stopSTL13:37Tue, May 14|Detroit - St. Louis|Spirit AirlinesUS$119US$119
- DTW21:161h 42mDirectSTL21:58Thu, Apr 4|Detroit - St. Louis|Delta Air LinesUS$122US$122
- DTW10:5024h 28m1 stopSTL10:18Wed, Apr 10|Detroit - St. Louis|Frontier AirlinesUS$126US$126
- DTT13:003h 5mDirectSTL14:00Thu, Apr 4|Detroit - St. Louis|Spirit AirlinesFind More FlightsFind More Flights
Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.
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Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.
Cheapest airlines flights from Detroit to St. Louis
Compare prices, find the option that best suits your travel needs, and enjoy a comfortable journey with a trusted airline.
Spirit Airlines
From US$103
Frontier Airlines
From US$105
Southwest Airlines
From US$108
Delta Air Lines
From US$122
United Airlines
From US$130
American Airlines
From US$147
Sun Country Airlines
From US$171
Alaska Airlines
From US$234
ANA airlines
Find more flights and airlines
Find cheap flights from Detroit to St. Louis by different airports
Searching for potential routes that might be cheaper and faster? Check out these alternative flights from Detroit to St. Louis.
- CheapestDTW05:006h 35m1 transferSTL10:35Detroit Metropolitan Wayne County Airport - St. Louis Lambert International AirportWed, May 15Spirit AirlinesUS$103
- DTW05:006h 35m1 transferSTL10:35Detroit Metropolitan Wayne County Airport - St. Louis Lambert International AirportWed, May 15Spirit AirlinesUS$103Find More Flights
Frequently Asked Questions
Detroit to St. Louis Flight Information
Cheapest nonstop flight price | $102 |
---|---|
Cheapest round-trip ticket price | $200 |
Off-season for travel | November |
Peak season for travel | September |
Plan Your Trip Around St. Louis
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