Search cheap flights from Grand Cayman to Santo Domingo in the next 3 months. Based on Trip.com's latest 7-day data, one-way fares start at US$351, and round-trip tickets start at US$767.

Cheapest airlines flights from Grand Cayman to Santo Domingo

You can choose from 1 airlines that fly from Grand Cayman to Santo Domingo, including Cayman Airways, Cayman Airways has lowest fares on this route.
Cayman Airways logo Cayman Airways
Airlines are determined based on actual purchased flight tickets from Grand Cayman to Santo Domingo according to previous 12 months data from Trip.com.

Grand Cayman to Santo Domingo Flight Details

The distance between Grand Cayman and Santo Domingo is about 1,208.77 km. Based on Trip.com's latest data, travel demand is highest in October. The off-season for travel is December.

Cheapest one-way flight priceUS$351
Cheapest return ticket priceUS$767
Cheapest monthDecember
Peak season for travelOctober
Flight distance1,208.77 km
Popular airlineCayman Airways
Flight statistics for the Grand Cayman–Santo Domingo route are based on aggregated booking data from Trip.com over the past 12 months.

Frequently Asked Questions

  • What are the cheapest flights from Grand Cayman to Santo Domingo (GCM-SDQ)?

    Based on Trip.com data, Cayman Airways offers one-way fares as low as US$351 on Cheapest nonstop routes (e.g. GCM to SDQ on Mon, Aug 17), while American Airlines offers Cheapest nonstop round-trips from US$767 departing on Sat, Jul 18 and returning on Sun, Jul 26.
  • At the moment, several airlines serve connecting flights from Grand Cayman to Santo Domingo, including: Cayman Airways Selected airlines are based on historical data collected from flight bookings made by users on Trip.com within the last 90 days.
  • By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Grand Cayman to Santo Domingo is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.
  • To find best deals on flights from Grand Cayman to Santo Domingo, you can use various tools on Trip.com:
    · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Mon, Aug 17, with one-way flights priced at just US$351.
    · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is Cayman Airways.
    · Set up price alerts to easily monitor ticket prices without having to check every day.
    · Check Trip.com flight deals and promo codes frequently.
    · Avoid peak season unless you book very early. It seems the peak season for Santo Domingo travel is around October.
    · Get exclusive promo codes for Trip.com app users.
  • The cheapest months to fly from Grand Cayman to Santo Domingo is December, when demand for travel is lower.
  • After crunching the numbers on our July flight calendar, it's currently cheapest to fly from Grand Cayman to Santo Domingo on July 20, 2026 with Cayman Airways, with prices starting at US$369.
  • You can land at any one of the following hubs in Santo Domingo, with Owen Roberts International Airport to Las Américas International Airport (GCM-SDQ) is by far the most common option on this route: La Isabela International Airport (JBQ) Las Américas International Airport (SDQ).
  • The time difference between Santo Domingo and Grand Cayman is 1h.
  • Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.

Note: Prices shown on this page are the estimated lowest prices found in the last 24 hours and include all taxes and fees.

Book with no extra fees

Prices displayed on this page are all-inclusive (incl. taxes, fuel surcharges, Civil Aviation Development Fund, etc.), and all fees are clearly shown before you pay. Charges for checked baggage, onboard meals, Wi‑Fi, and other optional services are also included where applicable in the flight cards.

Real-time pricing updates

Prices, availability, and travel details on this page have been updated within the last 24 hours, and for many routes are refreshed in real time. The more popular the route, the more accurate and up-to-date the data.

Change & Cancellation Policy

Trip.com shows the change and cancellation rules for each ticket during the booking process, including all related fees and conditions. Please refer to the following scenarios:
Voluntary cancellation/change:
To request a change or cancellation, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and flight segment, and submit your request. Please note that additional charges may apply based on the airline’s fare rules.
Cancellation/change due to a flight schedule change:
If your flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For full details of change and cancellation policies, please refer to the customer support pages.