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Find cheap one-way flights from Key West to Columbia starting at US$665.

We've found these cheap flights for you. You can book one-way or round-trip flight tickets.

  • Round-trip

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

When is the cheapest time to book flights from Key West to Columbia?

We monitor flight fares to help you find the best deals effortlessly

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Find cheap flights from Key West to Columbia by different airports

Searching for potential routes that might be cheaper and faster? Check out these alternative flights from Key West to Columbia.

  • Cheapest
    American Airlines
    EYW
    08:00
    7h 58m
    4 transfer
    COU
    14:58
    Key West International Airport - Columbia Regional Airport
    Wed, Apr 10American Airlines
    US$665
  • American Airlines
    EYW
    08:00
    7h 58m
    4 transfer
    COU
    14:58
    Key West International Airport - Columbia Regional Airport
    Wed, Apr 10American Airlines
    US$665
    Find More Flights

Frequently Asked Questions

  • When are flight tickets from Key West (EYW) to Columbia (COU) the cheapest?

    Airlines adjust prices for flights from Key West to Columbia based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.
  • How much do flights from Key West (EYW) to Columbia (COU) cost?

    According to Trip.com's data, the lowest price is around $734.

Key West to Columbia Flight Information

Off-season for travel

March

Peak season for travel

November