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Flights from Los Angeles to Knoxville

Cheapest airlines flights from Los Angeles to Knoxville

You can choose from 2 airlines that fly from Los Angeles to Knoxville, including Delta Air Lines, American Airlines, Delta Air Lines has lowest fares on this route.
Delta Air Lines logo Delta Air Lines
American Airlines logo American Airlines
Airlines are determined based on actual purchased flight tickets from Los Angeles to Knoxville according to previous 12 months data from Trip.com.

Search cheap flights from Los Angeles to Knoxville in the next 3 months. Based on Trip.com's latest 7-day data, one-way fares start at US$166, and round-trip tickets start at US$386.

      • LAX 07:15
        7h 42m
        1 stop
        TYS 17:57
        Los Angeles - Knoxville | Fri, Jun 19 | Delta Air Lines
        TYS 19:43
        7h 39m
        1 stop
        LAX 00:22
        Knoxville - Los Angeles | Thu, Jun 25 | Delta Air Lines
        US$386 US$632
        39% off
        39% off
        US$632 US$386
      • LAX 06:30
        10h 7m
        1 stop
        TYS 19:37
        Los Angeles - Knoxville | Mon, Jun 15 | Frontier Airlines
        TYS 06:00
        9h 40m
        1 stop
        LAX 12:40
        Knoxville - Los Angeles | Sat, Jun 20 | American Airlines
        US$387 US$632
        39% off
        39% off
        US$632 US$387
      • LAX 06:30
        10h 7m
        1 stop
        TYS 19:37
        Los Angeles - Knoxville | Thu, Jun 25 | Frontier Airlines
        TYS 06:00
        9h 40m
        1 stop
        LAX 12:40
        Knoxville - Los Angeles | Sat, Jun 27 | American Airlines
        US$431 US$632
        32% off
        32% off
        US$632 US$431
      • LAX 06:30
        10h 7m
        1 stop
        TYS 19:37
        Los Angeles - Knoxville | Sat, Jun 20 | Frontier Airlines
        TYS 20:32
        15h 26m
        1 stop
        LAX 08:58
        Knoxville - Los Angeles | Thu, Jun 25 | Frontier Airlines
        US$434
        31% off
        US$632 US$434
      • LAX 05:30
        9h 27m
        1 stop
        TYS 17:57
        Los Angeles - Knoxville | Sat, Jun 20 | Delta Air Lines
        TYS 19:43
        7h 39m
        1 stop
        LAX 00:22
        Knoxville - Los Angeles | Thu, Jun 25 | Delta Air Lines
        US$445
        30% off
        US$632 US$445
      • LAX 23:55
        8h 18m
        1 stop
        TYS 11:13
        Los Angeles - Knoxville | Thu, Jun 25 | American Airlines
        TYS 06:00
        9h 40m
        1 stop
        LAX 12:40
        Knoxville - Los Angeles | Sat, Jun 27 | American Airlines
        US$456
        28% off
        US$632 US$456
      • LAX 23:55
        8h 18m
        1 stop
        TYS 11:13
        Los Angeles - Knoxville | Fri, Jun 19 | American Airlines
        TYS 20:32
        15h 26m
        1 stop
        LAX 08:58
        Knoxville - Los Angeles | Thu, Jun 25 | Frontier Airlines
        US$460
        27% off
        US$632 US$460
      • LAX 06:30
        10h 7m
        1 stop
        TYS 19:37
        Los Angeles - Knoxville | Sat, Jun 13 | Frontier Airlines
        TYS 05:37
        7h 17m
        1 stop
        LAX 09:54
        Knoxville - Los Angeles | Fri, Jun 19 | American Airlines
        US$471
        25% off
        US$632 US$471
      • LAX 07:30
        9h 7m
        1 stop
        TYS 19:37
        Los Angeles - Knoxville | Mon, Jun 15 | American Airlines
        TYS 06:00
        9h 40m
        1 stop
        LAX 12:40
        Knoxville - Los Angeles | Sat, Jun 20 | American Airlines
        US$480
        24% off
        US$632 US$480
      • LAX 13:00
        17h 25m
        1 stop
        TYS 14:00
        Los Angeles - Knoxville | Fri, Jun 12 | Normal Airline
        TYS 15:00
        6h
        Nonstop
        LAX 16:00
        Knoxville - Los Angeles | Sun, Jun 14 | Normal Airline
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      • LAX 11:16
        8h 44m
        1 stop
        TYS 23:00
        Los Angeles - Knoxville | Wed, Aug 5 | Delta Air Lines
        US$166 US$287
        42% off
        42% off
        US$287 US$166
      • LAX 05:30
        9h 32m
        1 stop
        TYS 18:02
        Los Angeles - Knoxville | Tue, Jun 23 | Delta Air Lines
        US$170 US$287
        41% off
        41% off
        US$287 US$170
      • LAX 20:56
        19h 40m
        1 stop
        TYS 19:36
        Los Angeles - Knoxville | Thu, Aug 6 | Frontier Airlines
        US$173 US$287
        40% off
        40% off
        US$287 US$173
      • LAX 11:45
        9h 14m
        1 stop
        TYS 23:59
        Los Angeles - Knoxville | Wed, Aug 5 | American Airlines
        US$176
        39% off
        US$287 US$176
      • LAX 14:54
        25h 43m
        1 stop
        TYS 19:37
        Los Angeles - Knoxville | Sun, Jun 21 | Frontier Airlines
        US$204
        28% off
        US$287 US$204
      • LAX 05:30
        9h 32m
        1 stop
        TYS 18:02
        Los Angeles - Knoxville | Tue, Jun 30 | Delta Air Lines
        US$205
        28% off
        US$287 US$205
      • LAX 11:45
        9h 14m
        1 stop
        TYS 23:59
        Los Angeles - Knoxville | Sat, Aug 8 | American Airlines
        US$205
        28% off
        US$287 US$205
      • LAX 23:59
        8h 12m
        1 stop
        TYS 11:11
        Los Angeles - Knoxville | Thu, Aug 6 | Delta Air Lines
        US$216
        25% off
        US$287 US$216
      • LAX 11:40
        8h 32m
        1 stop
        TYS 23:12
        Los Angeles - Knoxville | Wed, Aug 5 | United Airlines
        US$217
        24% off
        US$287 US$217
      • LAX 06:30
        9h 54m
        1 stop
        TYS 19:24
        Los Angeles - Knoxville | Wed, Aug 5 | Frontier Airlines
        US$218
        24% off
        US$287 US$218
      • LAX 13:00
        17h 25m
        1 stop
        TYS 14:00
        Los Angeles - Knoxville | Fri, Jun 12 | Normal Airline
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Displayed flight fares from Los Angeles to Knoxville are based on average prices across airlines for the next 3 months, according to the latest Trip.com database.

Los Angeles to Knoxville Flight Details

The distance between Los Angeles and Knoxville is about 3,129.61 km. Based on Trip.com's latest data, travel demand is highest in January. The off-season for travel is November.

Cheapest one-way flight priceUS$166
Cheapest return ticket priceUS$386
Cheapest monthNovember
Peak season for travelJanuary
Flight distance3,129.61 km
Popular airlineDelta Air Lines
Flight statistics for the Los Angeles–Knoxville route are based on aggregated booking data from Trip.com over the past 12 months.

Frequently Asked Questions

  • What are the cheapest flights from Los Angeles to Knoxville (LAX-TYS)?

    Based on Trip.com data, Delta Air Lines offers one-way fares as low as US$166 on Cheapest nonstop routes (e.g. LAX to TYS on Wed, Aug 5), while Delta Air Lines offers Cheapest nonstop round-trips from US$386 departing on Fri, Jun 19 and returning on Thu, Jun 25.
  • At the moment, several airlines serve connecting flights from Los Angeles to Knoxville, including: American Airlines Delta Air Lines Selected airlines are based on historical data collected from flight bookings made by users on Trip.com within the last 90 days.
  • By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Los Angeles to Knoxville is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.
  • To find best deals on flights from Los Angeles to Knoxville, you can use various tools on Trip.com:
    · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Wed, Aug 5, with one-way flights priced at just US$166.
    · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is Delta Air Lines.
    · Set up price alerts to easily monitor ticket prices without having to check every day.
    · Check Trip.com flight deals and promo codes frequently.
    · Avoid peak season unless you book very early. It seems the peak season for Knoxville travel is around January.
    · Get exclusive promo codes for Trip.com app users.
  • The cheapest months to fly from Los Angeles to Knoxville is November, when demand for travel is lower.
  • After crunching the numbers on our June flight calendar, it's currently cheapest to fly from Los Angeles to Knoxville on June 18, 2026 with Frontier Airlines, with prices starting at US$167.
  • You can land at any one of the following hubs in Knoxville, with Ontario International Airport to Mcghee Tyson Airport (ONT-TYS) is by far the most common option on this route: Mcghee Tyson Airport (TYS).
  • The time difference between Knoxville and Los Angeles is 3h.
  • Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.

Trip.com Airline Insights on Flights from Los Angeles to Knoxville

Which airline offers the cheapest direct flights from Los Angeles to Knoxville?

Data is based on the average price of all nonstop flights from Los Angeles to Knoxville on Trip.com over the past 12 months.

Based on Trip.com’s data from the past 12 months, United Airlines provides the lowest-priced direct flights from Los Angeles to Knoxville, with fares starting at US$185.

US$126
US$185
US$245
US$305
US$364
United Airlines
US$185
United Airlines
Delta Air Lines
US$231
Delta Air Lines
Frontier Airlines
US$267
Frontier Airlines
American Airlines
US$364
American Airlines

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Note: Prices shown on this page are the estimated lowest prices found in the last 24 hours and include all taxes and fees.

Book with no extra fees

Prices displayed on this page are all-inclusive (incl. taxes, fuel surcharges, Civil Aviation Development Fund, etc.), and all fees are clearly shown before you pay. Charges for checked baggage, onboard meals, Wi‑Fi, and other optional services are also included where applicable in the flight cards.

Real-time pricing updates

Prices, availability, and travel details on this page have been updated within the last 24 hours, and for many routes are refreshed in real time. The more popular the route, the more accurate and up-to-date the data.

Change & Cancellation Policy

Trip.com shows the change and cancellation rules for each ticket during the booking process, including all related fees and conditions. Please refer to the following scenarios:
Voluntary cancellation/change:
To request a change or cancellation, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and flight segment, and submit your request. Please note that additional charges may apply based on the airline’s fare rules.
Cancellation/change due to a flight schedule change:
If your flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For full details of change and cancellation policies, please refer to the customer support pages.