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Find cheap one-way flights from Madrid to Santiago starting at US$275.

We've found these cheap flights for you. You can book one-way or round-trip flight tickets.

  • One way
  • Round-trip

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

When is the cheapest time to book flights from Madrid to Santiago?

We monitor flight fares to help you find the best deals effortlessly

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.
Cheapest airlines flights from Madrid to Santiago

Compare prices, find the option that best suits your travel needs, and enjoy a comfortable journey with a trusted airline.

Avianca
From US$280
LATAM Airlines
From US$284
Air Europa
From US$377
Iberia
From US$387
Vueling Airlines
From US$398
easyJet
From US$423
TAP Air Portugal
From US$447
Aerolineas Argentinas
From US$456
Plus Ultra Lineas Aereas
From US$503
Transavia France
From US$504
ANA airlines

Find more flights and airlines

Find cheap flights from Madrid to Santiago by different airports

Searching for potential routes that might be cheaper and faster? Check out these alternative flights from Madrid to Santiago.

  • Cheapest
    LATAM Airlines
    MAD
    13:25
    13h 25m
    Direct
    SCL
    20:50
    Madrid Barajas Airport - Arturo Merino Benitez Airport
    Fri, May 10LATAM Airlines
    US$284
  • LATAM Airlines
    MAD
    13:25
    13h 25m
    Direct
    SCL
    20:50
    Madrid Barajas Airport - Arturo Merino Benitez Airport
    Fri, May 10LATAM Airlines
    US$284
    Find More Flights

Frequently Asked Questions

  • When are flight tickets from Madrid (MAD) to Santiago (SCL) the cheapest?

    Airlines adjust prices for flights from Madrid to Santiago based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.
  • How much do flights from Madrid (MAD) to Santiago (SCL) cost?

    According to Trip.com's data, the lowest price is around $1,105.
  • How long does it take to fly from Madrid (MAD) to Santiago (SCL) and what is the distance?

    It takes around 13 hours 39 minutes to fly from Madrid (MAD) to Santiago (SCL).
  • What is the transportation method from the main airport to downtown in Santiago?

    • The distance from Arturo Merino Benitez Airport to downtown is about 13km. It takes about 30 minutes by taxi.
  • What are the most popular airlines that fly from Madrid (MAD) to Santiago (SCL)?

    Airlines with flights from Madrid (MAD) to Santiago (SCL): Finnair, Qatar Airways, British Airways, El Al, Japan Airlines, Iberia, LATAM Airlines and Cathay Pacific.

Madrid to Santiago Flight Information

Cheapest nonstop flight price

$275

Cheapest round-trip ticket price

$690

Off-season for travel

May

Peak season for travel

September