Cheap Flights from Medellin to Cali from US$18

Frequently Asked Questions

• What are the cheapest flights from Medellin to Cali (MDE-CLO)?

  Based on Trip.com data, JetSMART Airlines offers one-way fares as low as US$18 on Cheapest nonstop routes (e.g. MDE to CLO on Fri, Nov 27), while JetSMART Airlines offers Cheapest nonstop round-trips from US$28 departing on Sun, Oct 25 and returning on Sun, Nov 1.

• Which airlines offer direct flights from Medellin to Cali?

  At the moment, you can catch a nonstop flight from Medellin to Cali with the following airlines, including: JetSMART LATAM Airlines avianca Selected airlines are based on historical data collected from flight bookings users made on Trip.com within the last 90 days.

• How long is a flight from Medellin to Cali?

  It takes about 1 hour 9 minutes to fly from Medellin to Cali.

• When is the best time to book flights from Medellin to Cali?

  By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Medellin to Cali is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.

• How many flights are there per week from Medellin to Cali?

  Based on Trip.com data in the past 4 weeks, there is 47 flight per week flying from Medellin to Cali. You can check the weekly schedule for popular airlines on this route below: LATAM Airlines: S/M/T/W/T/F/S -- LA4344 (06:19) avianca: S/M/T/W/T/F/S -- AV9439 (22:09)

• How can I find the best deals on flights from Medellin to Cali?

  To find best deals on flights from Medellin to Cali, you can use various tools on Trip.com:
  · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Fri, Nov 27, with one-way flights priced at just US$18.
  · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is JetSMART Airlines.
  · Set up price alerts to easily monitor ticket prices without having to check every day.
  · Check Trip.com flight deals and promo codes frequently.
  · Avoid peak season unless you book very early. It seems the peak season for Cali travel is around January.
  · Get exclusive promo codes for Trip.com app users.

• When are flight tickets from Medellin (MDE) to Cali (CLO) the cheapest?

  The cheapest months to fly from Medellin to Cali is September, when demand for travel is lower.

• Which upcoming date is cheapest to fly from Medellin to Cali on?

  After crunching the numbers on our October flight calendar, it's currently cheapest to fly from Medellin to Cali on October 23, 2026 with JetSMART, with prices starting at US$18.

• Which airports fly into Cali from Medellin?

  You can land at any one of the following hubs in Cali: Alfonso Bonilla Aragón International Airport (CLO). Flying from Jose Maria Cordova International Airport to Alfonso Bonilla Aragón International Airport (MDE-CLO) is by far the most common option on this route.

• Is there any time difference between Medellin and Cali?

  The time difference between Cali and Medellin is 0m.

• How do I change or cancel my ticket from Medellin to Cali?

  Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.

• What is the average cost of a one-way flight from Medellin to Cali?

  Based on Trip.com data for flights departing in the next 30 days, the average one-way fare from Medellin to Cali is US$79. Fares vary by travel date, airline and availability.

• What is the average cost of a round-trip flight from Medellin to Cali?

  Based on Trip.com data for travel in the next 30 days, the average round-trip fare from Medellin to Cali is US$108. The final price depends on the outbound and return dates, airline and fare conditions.

• How do I book flights from Medellin to Cali on Trip.com?

  Enter Medellin and Cali, choose your travel dates and passengers, then compare flights by price, duration and baggage. Select a fare, review the change and cancellation rules, enter traveler details and complete payment to receive your confirmation.

• Are there budget airlines on the Medellin to Cali route?

  JetSMART and Clic Airare the most popular budget airlines flying from Medellin to Cali. Check baggage, seat and payment fees before comparing the final price.