Cheapest airlines flights from Mexico City to Panama City
Find Cheapest Flights from Mexico City to Panama City
Search for direct flights from Mexico City to Panama City in the next 3 months. Based on Trip.com's latest 7-day flight data, one-way direct flights start at US$127, and round-trip direct flights start at US$201.
- Round-trip
- One way
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Cheapest nonstop
MEX 15:303h 37mNonstopPTY 20:07Mexico City - Panama City | Sat, Jan 24 | Copa Airlines
PTY 18:584h 7mNonstopMEX 22:05Panama City - Mexico City | Sat, Jan 31 | Copa AirlinesUS$201 US$29933% OFF33% OFFUS$299 US$201 -
MEX 08:553h 45mNonstopPTY 13:40Mexico City - Panama City | Wed, Dec 31 | Aeromexico
PTY 14:554h 5mNonstopMEX 18:00Panama City - Mexico City | Thu, Jan 8 | AeromexicoUS$242 US$29919% OFF19% OFFUS$299 US$242 -
MEX 15:303h 45mNonstopPTY 20:15Mexico City - Panama City | Mon, Dec 22 | Copa Airlines
PTY 22:143h 46mNonstopMEX 01:00Panama City - Mexico City | Mon, Dec 29 | Copa AirlinesUS$245 US$29918% OFF18% OFFUS$299 US$245 -
MEX 08:553h 45mNonstopPTY 13:40Mexico City - Panama City | Mon, Jan 5 | Aeromexico
PTY 14:463h 59mNonstopMEX 17:45Panama City - Mexico City | Mon, Jan 12 | AeromexicoUS$24717% OFFUS$299 US$247 -
MEX 08:553h 45mNonstopPTY 13:40Mexico City - Panama City | Fri, Jan 9 | Aeromexico
PTY 15:023h 38mNonstopMEX 17:40Panama City - Mexico City | Fri, Jan 16 | AeromexicoUS$25116% OFFUS$299 US$251 -
MEX 08:553h 45mNonstopPTY 13:40Mexico City - Panama City | Wed, Dec 24 | Aeromexico
PTY 14:554h 5mNonstopMEX 18:00Panama City - Mexico City | Thu, Dec 25 | AeromexicoUS$25216% OFFUS$299 US$252 -
MEX 08:553h 52mNonstopPTY 13:47Mexico City - Panama City | Mon, Jan 12 | Aeromexico
PTY 15:023h 38mNonstopMEX 17:40Panama City - Mexico City | Mon, Jan 19 | AeromexicoUS$25216% OFFUS$299 US$252 -
MEX 08:553h 45mNonstopPTY 13:40Mexico City - Panama City | Thu, Jan 1 | Aeromexico
PTY 15:004h 5mNonstopMEX 18:05Panama City - Mexico City | Thu, Jan 8 | AeromexicoUS$26910% OFFUS$299 US$269 -
MEX 15:303h 45mNonstopPTY 20:15Mexico City - Panama City | Wed, Dec 24 | Copa Airlines
PTY 22:143h 46mNonstopMEX 01:00Panama City - Mexico City | Sun, Dec 28 | Copa AirlinesUS$2758% OFFUS$299 US$275 -
MEX 23:1016h 45m1 stopPTY 16:55Mexico City - Panama City | Wed, Jan 14 | avianca
PTY 02:5510h 15m1 stopMEX 12:10Panama City - Mexico City | Thu, Jan 22 | aviancaUS$26910% OFFUS$299 US$269 -
MEX 13:0017h 25m1 stopPTY Invalid DateMexico City - Panama City | Fri, Dec 19 | Normal Airline
PTY 15:006hNonstopMEX 16:00Panama City - Mexico City | Sun, Dec 21 | Normal AirlineFind More FlightsFind More Flights
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Cheapest nonstop
MEX 08:553h 45mNonstopPTY 13:40Mexico City - Panama City | Thu, Jan 1 | AeromexicoUS$127 US$14914% OFF14% OFFUS$149 US$127 -
MEX 15:303h 45mNonstopPTY 20:15Mexico City - Panama City | Wed, Dec 31 | Copa AirlinesUS$132 US$14911% OFF11% OFFUS$149 US$132 -
MEX 15:303h 37mNonstopPTY 20:07Mexico City - Panama City | Thu, Jan 1 | Copa AirlinesUS$133 US$14910% OFF10% OFFUS$149 US$133 -
MEX 15:303h 45mNonstopPTY 20:15Mexico City - Panama City | Tue, Dec 30 | Copa AirlinesUS$13410% OFFUS$149 US$134 -
MEX 00:4015h 15m1 stopPTY 16:55Mexico City - Panama City | Fri, Jan 23 | aviancaUS$13310% OFFUS$149 US$133 -
MEX 00:4015h 15m1 stopPTY 16:55Mexico City - Panama City | Thu, Feb 5 | aviancaUS$13410% OFFUS$149 US$134 -
MEX 23:1013h 50m1 stopPTY 14:00Mexico City - Panama City | Mon, Feb 2 | aviancaUS$13410% OFFUS$149 US$134 -
MEX 00:4015h 15m1 stopPTY 16:55Mexico City - Panama City | Tue, Jan 13 | aviancaUS$1359% OFFUS$149 US$135 -
MEX 00:4015h 15m1 stopPTY 16:55Mexico City - Panama City | Sun, Jan 18 | aviancaUS$1359% OFFUS$149 US$135 -
MEX 05:008h1 stopPTY 14:00Mexico City - Panama City | Wed, Jan 28 | aviancaUS$1378% OFFUS$149 US$137 -
MEX 13:0017h 25m1 stopPTY Invalid DateMexico City - Panama City | Fri, Dec 19 | Normal AirlineFind More FlightsFind More Flights
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Displayed flight fares from Mexico City to Panama City are based on average prices across airlines for the next 3 months, according to the latest Trip.com database.
Mexico City to Panama City Flight Details
The distance between Mexico City and Panama City is about 2,403.84 km. The average flying time from Mexico City to Panama City is around 3 hours 44 minutes. Based on Trip.com's latest data, travel demand is highest in July. The off-season for travel is December.
| Cheapest one-way flight price | US$127 |
|---|---|
| Cheapest return ticket price | US$201 |
| Cheapest month | December |
| Peak season for travel | July |
| Flight distance | 2,403.84 km |
| Average flight time | 3 hours 44 minutes |
| Popular airline | Aeromexico |
When is the cheapest time to book flights from Mexico City to Panama City?
The cheapest time to fly from Mexico City to Panama City: Dec 28 to Jan 4 — one-way prices start at US$127.
Frequently Asked Questions
What are the cheapest flights from Mexico City to Panama City (MEX-PTY)?
Based on Trip.com data, Aeromexico offers one-way fares as low as US$127 on Cheapest nonstop routes (e.g. MEX to PTY on Thu, Jan 1), while Copa Airlines offers Cheapest nonstop round-trips from US$201 departing on Sat, Jan 24 and returning on Sat, Jan 31.Which airlines offer direct flights from Mexico City to Panama City?
At the moment, you can catch a nonstop flight from Mexico City to Panama City with the following airlines, including: Aeromexico Copa Airlines Selected airlines are based on historical data collected from flight bookings users made on Trip.com within the last 90 days.How long is a flight from Mexico City to Panama City?
It takes about 3 hours 44 minutes to fly from Mexico City to Panama City.When is the best time to book flights from Mexico City to Panama City?
By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Mexico City to Panama City is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.How many flights are there per week from Mexico City to Panama City?
Based on Trip.com data in the past 4 weeks, there is 46 flight per week flying from Mexico City to Panama City. You can check the weekly schedule for popular airlines on this route below: Copa Airlines: S/M/T/W/T/F/S -- CM137 (09:45) Copa Airlines: S/M/T/W/T/F/S -- CM195 (06:26) Aeromexico: S/M/T/W/T/F/S -- AM464 (09:26)How can I find the best deals on flights from Mexico City to Panama City?
To find best deals on flights from Mexico City to Panama City, you can use various tools on Trip.com:
· Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Thu, Jan 1, with one-way flights priced at just US$127.
· Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is Aeromexico.
· Set up price alerts to easily monitor ticket prices without having to check every day.
· Check Trip.com flight deals and promo codes frequently.
· Avoid peak season unless you book very early. It seems the peak season for Panama City travel is around July.
· Get exclusive promo codes for Trip.com app users.When are flight tickets from Mexico City (MEX) to Panama City (PTY) the cheapest?
The cheapest months to fly from Mexico City to Panama City is December, when demand for travel is lower.Which upcoming date is cheapest to fly from Mexico City to Panama City on?
After crunching the numbers on our December flight calendar, it's currently cheapest to fly from Mexico City to Panama City on December 31, 2025 with Aeromexico, with prices starting at US$241.Which airports can I fly to for Panama City from Mexico City?
You can land at any one of the following hubs in Panama City, with Mexico City International Airport to Tocumen International Airport (MEX-PTY) is by far the most common option on this route: Albrook "Marcos A. Gelabert" International Airport (PAC) Tocumen International Airport (PTY).Is there any time difference between Mexico City and Panama City?
The time difference between Panama City and Mexico City is 1h.How do I change or cancel my ticket from Mexico City to Panama City?
Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.
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