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Cheap Flights from Mexico City to Santiago

  • Mexico City Santiago

    Wed, Apr 1 - Sun, Apr 5

    From US$489.44
  • Mexico City Santiago

    Sun, Mar 15 - Sat, Mar 21

    From US$507.34
  • Mexico City Santiago

    Thu, Mar 19 - Tue, Mar 24

    From US$527.82
  • Mexico City Santiago

    Thu, Mar 19 - Tue, Mar 24

    From US$537.71
  • Mexico City Santiago

    Wed, Apr 1 - Sun, Apr 5

    From US$549.60
  • Mexico City Santiago

    Mon, Mar 2 - Sun, Mar 8

    From US$562.34

Prices shown are for 1 adult ticket including taxes & fees.(As ticket fares can change frequently, these advertised prices are for reference only. The actual prices will be shown at time of booking.)

Mexico City to Santiago Flight Information

Below are some common questions asked about this flight route:

When can I book the cheapest flight from Mexico City to Santiago?

Airlines adjust prices for plane tickets based on the day and time that you book your flight. After analyzing data from all airlines, we have discovered that the best days to book flights from Mexico City to Santiago are Tuesdays, Wednesdays, and Saturdays.

What are the airlines flying from Mexico City to Santiago?

Airlines flying from Mexico City to Santiago include Aerolineas Argentinas,LATAM Airlines,Interjet,Aeromexico,Westjet.

What is the most popular airline for non-stop flights from Mexico City to Santiago?

LAN Airlines provides 58 of the non-stop flights between Mexico City and Santiago.

How many airports are there in Santiago?

There are 1 airports in Santiago - Comodoro Arturo Merino Benítez Airport.

Average duration of direct flights: 7h57m
Airports at destination:
Flight route:
Price starting from:

Mexico City to Santiago Flight Schedule

Flight info. Departure
Arrival
Route Weekly Schedule
AM010
10:15 MEX 21:20 SCL
Mexico City to Santiago SMTWTFS Search
18:55 MEX 06:00 SCL
Mexico City to Santiago SMTWTFS Search
WS6115
10:15 MEX 20:10 SCL
Mexico City to Santiago SMTWTFS Search
4O9302
18:55 MEX 06:00 SCL
Mexico City to Santiago SMTWTFS Search
10:15 MEX 20:10 SCL
Mexico City to Santiago SMTWTFS Search
18:55 MEX 04:15 SCL
Mexico City to Santiago ------- Search
4O9077
19:30 MEX 05:40 SCL
Mexico City to Santiago ------- Search

Mexico City to Comodoro Arturo Merino Benítez Airport (SCL)

10:10, Mar 15 - 23:20, Mar 21
AM | Aeromexico
8h 10m
MEX - SCL
Nonstop
US$507
Round-trip from
Search
18:55, Mar 8 - 23:30, Mar 15
LA | LATAM Airlines
8h 5m
MEX - SCL
Nonstop
US$563
Round-trip from
Search
18:55, Mar 24 - 23:30, Mar 26
4O | Interjet
8h 5m
MEX - SCL
Nonstop
US$566
Round-trip from
Search
10:10, Mar 16 - 23:20, Mar 22
AM | Aeromexico
8h 10m
MEX - SCL
Nonstop
US$507
Round-trip from
Search
10:10, Mar 20 - 23:20, Mar 27
AM | Aeromexico
8h 10m
MEX - SCL
Nonstop
US$507
Round-trip from
Search

Prices shown are for 1 adult ticket including taxes & fees.(As ticket fares can change frequently, these advertised prices are for reference only. The actual prices will be shown at time of booking.)

Roundtrip vs One-Way Flights from Mexico City to Santiago

There is usually no major price difference between buying a roundtrip flight versus a one-way flight. Increased flexibility is the main benefit when it comes to buying a one-way flight from Mexico City to Santiago. However, booking a roundtrip flight is a simpler process. You can compare roundtrip and one-way flights by using our flight comparison tool.

Travel from Mexico City to Santiago

Santiago attracts thousands of visitors every year for both business and pleasure. Planning a trip from Mexico City to Santiago is easy when you use Trip.com to help you make travel arrangements. With Trip.com, you can search for available flights and hotel rooms, and then make your booking quickly and easily online.

A Trip to Remember

Make your journey from Mexico City to Santiago a trip to remember when you use Trip.com to review city attractions before you arrive. With a preview of what's available at your destination, you can make any necessary reservations in advance for the best travel experience possible.