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Flights from Midland to Knoxville

Search cheap flights from Midland to Knoxville in the next 3 months. Based on Trip.com's latest 7-day data, one-way fares start at US$210, and round-trip tickets start at US$408.

      • MAF 13:45
        7h 38m
        1 stop
        TYS 22:23
        Midland - Knoxville | Mon, May 18 | United Airlines
        TYS 07:15
        4h 52m
        1 stop
        MAF 11:07
        Knoxville - Midland | Sun, May 24 | United Airlines
        US$408 US$1,682
        76% off
        76% off
        US$1,682 US$408
      • MAF 13:45
        7h 34m
        1 stop
        TYS 22:19
        Midland - Knoxville | Mon, May 25 | United Airlines
        TYS 07:15
        7h 20m
        1 stop
        MAF 13:35
        Knoxville - Midland | Sat, May 30 | United Airlines
        US$542 US$1,682
        68% off
        68% off
        US$1,682 US$542
      • MAF 05:00
        7h 34m
        1 stop
        TYS 13:34
        Midland - Knoxville | Tue, May 12 | United Airlines
        TYS 15:30
        7h 16m
        1 stop
        MAF 21:46
        Knoxville - Midland | Sat, May 16 | United Airlines
        US$578 US$1,682
        66% off
        66% off
        US$1,682 US$578
      • MAF 06:02
        5h 28m
        1 stop
        TYS 12:30
        Midland - Knoxville | Mon, May 18 | American Airlines
        TYS 13:53
        5h 19m
        1 stop
        MAF 18:12
        Knoxville - Midland | Fri, May 22 | American Airlines
        US$659
        61% off
        US$1,682 US$659
      • MAF 18:16
        4h 40m
        1 stop
        TYS 23:56
        Midland - Knoxville | Fri, May 15 | American Airlines
        TYS 18:54
        6h 12m
        1 stop
        MAF 00:06
        Knoxville - Midland | Mon, May 18 | American Airlines
        US$678
        60% off
        US$1,682 US$678
      • MAF 06:00
        6h 2m
        1 stop
        TYS 13:02
        Midland - Knoxville | Fri, Jun 12 | American Airlines
        TYS 17:33
        6h 43m
        1 stop
        MAF 23:16
        Knoxville - Midland | Sun, Jun 14 | American Airlines
        US$680
        60% off
        US$1,682 US$680
      • MAF 14:15
        7h 57m
        1 stop
        TYS 23:12
        Midland - Knoxville | Wed, May 27 | United Airlines
        TYS 16:56
        27h 43m
        1 stop
        MAF 19:39
        Knoxville - Midland | Mon, Jun 1 | United Airlines
        US$803
        52% off
        US$1,682 US$803
      • MAF 05:00
        5h 19m
        1 stop
        TYS 11:19
        Midland - Knoxville | Tue, May 26 | United Airlines
        TYS 15:25
        7h 32m
        1 stop
        MAF 21:57
        Knoxville - Midland | Tue, May 26 | United Airlines
        US$893
        47% off
        US$1,682 US$893
      • MAF 07:00
        5h 34m
        1 stop
        TYS 13:34
        Midland - Knoxville | Fri, May 15 | United Airlines
        TYS 16:20
        6h 55m
        1 stop
        MAF 22:15
        Knoxville - Midland | Tue, May 19 | United Airlines
        US$950
        44% off
        US$1,682 US$950
      • MAF 14:15
        7h 57m
        1 stop
        TYS 23:12
        Midland - Knoxville | Fri, Jun 12 | United Airlines
        TYS 08:48
        8h 48m
        1 stop
        MAF 16:36
        Knoxville - Midland | Sun, Jun 14 | United Airlines
        US$1,177
        30% off
        US$1,682 US$1,177
      • MAF 13:00
        17h 25m
        1 stop
        TYS 14:00
        Midland - Knoxville | Tue, May 12 | Normal Airline
        TYS 15:00
        6h
        Nonstop
        MAF 16:00
        Knoxville - Midland | Thu, May 14 | Normal Airline
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      • MAF 13:45
        7h 38m
        1 stop
        TYS 22:23
        Midland - Knoxville | Mon, May 18 | United Airlines
        US$210 US$808
        74% off
        74% off
        US$808 US$210
      • MAF 17:13
        4h 59m
        1 stop
        TYS 23:12
        Midland - Knoxville | Mon, May 25 | United Airlines
        US$324 US$808
        60% off
        60% off
        US$808 US$324
      • MAF 11:39
        6h 52m
        1 stop
        TYS 19:31
        Midland - Knoxville | Mon, May 25 | American Airlines
        US$329 US$808
        59% off
        59% off
        US$808 US$329
      • MAF 07:00
        5h 34m
        1 stop
        TYS 13:34
        Midland - Knoxville | Fri, May 15 | United Airlines
        US$565
        30% off
        US$808 US$565
      • MAF 13:00
        17h 25m
        1 stop
        TYS 14:00
        Midland - Knoxville | Tue, May 12 | Normal Airline
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Displayed flight fares from Midland to Knoxville are based on average prices across airlines for the next 3 months, according to the latest Trip.com database.

Frequently Asked Questions

  • What are the cheapest flights from Midland to Knoxville (MAF-TYS)?

    Based on Trip.com data, United Airlines offers one-way fares as low as US$210 on Cheapest nonstop routes (e.g. MAF to TYS on Mon, May 18), while United Airlines offers Cheapest nonstop round-trips from US$408 departing on Mon, May 18 and returning on Sun, May 24.
  • By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Midland to Knoxville is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.
  • To find best deals on flights from Midland to Knoxville, you can use various tools on Trip.com:
    · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Mon, May 18, with one-way flights priced at just US$210.
    · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is United Airlines.
    · Set up price alerts to easily monitor ticket prices without having to check every day.
    · Check Trip.com flight deals and promo codes frequently.
    · Avoid peak season unless you book very early. It seems the peak season for Knoxville travel is around November.
    · Get exclusive promo codes for Trip.com app users.
  • The cheapest months to fly from Midland to Knoxville is September, when demand for travel is lower.
  • After crunching the numbers on our May flight calendar, it's currently cheapest to fly from Midland to Knoxville on May 18, 2026 with United Airlines, with prices starting at US$408.
  • The time difference between Knoxville and Midland is 1h.
  • Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.

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Note: Prices shown on this page are the estimated lowest prices found in the last 24 hours and include all taxes and fees.

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Prices displayed on this page are all-inclusive (incl. taxes, fuel surcharges, Civil Aviation Development Fund, etc.), and all fees are clearly shown before you pay. Charges for checked baggage, onboard meals, Wi‑Fi, and other optional services are also included where applicable in the flight cards.

Real-time pricing updates

Prices, availability, and travel details on this page have been updated within the last 24 hours, and for many routes are refreshed in real time. The more popular the route, the more accurate and up-to-date the data.

Change & Cancellation Policy

Trip.com shows the change and cancellation rules for each ticket during the booking process, including all related fees and conditions. Please refer to the following scenarios:
Voluntary cancellation/change:
To request a change or cancellation, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and flight segment, and submit your request. Please note that additional charges may apply based on the airline’s fare rules.
Cancellation/change due to a flight schedule change:
If your flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For full details of change and cancellation policies, please refer to the customer support pages.