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Flights from Milan to Charleston

Explore the cheapest one-way and round-trip flights from Milan to Charleston over the next 90 days, with one-way fares from US$510 and round-trip from US$742. Based on Trip.com's latest 7-day flight data.

      • MXP 13:20
        16h 23m
        1 stop
        CHS 23:43
        Milan - Charleston | Fri, Sep 25 | American Airlines
        CHS 06:00
        21h 5m
        1 stop
        MXP 09:05
        Charleston - Milan | Fri, Oct 2 | American Airlines
        US$742 US$969
        23% off
        23% off
        US$969 US$742
      • MXP 13:20
        16h 39m
        1 stop
        CHS 23:59
        Milan - Charleston | Fri, Nov 6 | British Airways
        CHS 07:27
        22h 13m
        1 stop
        MXP 11:40
        Charleston - Milan | Fri, Nov 13 | British Airways
        US$746 US$969
        23% off
        23% off
        US$969 US$746
      • MXP 13:20
        34h 48m
        1 stop
        CHS 18:08
        Milan - Charleston | Fri, Sep 25 | British Airways
        CHS 16:30
        13h
        1 stop
        MXP 11:30
        Charleston - Milan | Wed, Sep 30 | British Airways
        US$751 US$969
        22% off
        22% off
        US$969 US$751
      • MXP 13:20
        15h 39m
        1 stop
        CHS 23:59
        Milan - Charleston | Wed, Oct 28 | British Airways
        CHS 11:41
        17h 49m
        1 stop
        MXP 11:30
        Charleston - Milan | Tue, Nov 3 | British Airways
        US$754
        22% off
        US$969 US$754
      • MXP 13:20
        16h 39m
        1 stop
        CHS 23:59
        Milan - Charleston | Fri, Oct 16 | British Airways
        CHS 11:12
        18h 18m
        1 stop
        MXP 11:30
        Charleston - Milan | Tue, Oct 20 | British Airways
        US$755
        22% off
        US$969 US$755
      • MXP 13:20
        16h 23m
        1 stop
        CHS 23:43
        Milan - Charleston | Fri, Oct 2 | British Airways
        CHS 11:12
        18h 18m
        1 stop
        MXP 11:30
        Charleston - Milan | Fri, Oct 9 | British Airways
        US$756
        22% off
        US$969 US$756
      • MXP 14:20
        14h 36m
        1 stop
        CHS 23:56
        Milan - Charleston | Fri, Oct 30 | British Airways
        CHS 11:41
        17h 49m
        1 stop
        MXP 11:30
        Charleston - Milan | Tue, Nov 3 | British Airways
        US$756
        22% off
        US$969 US$756
      • MXP 13:20
        15h 39m
        1 stop
        CHS 23:59
        Milan - Charleston | Wed, Oct 28 | American Airlines
        CHS 10:55
        17h 10m
        1 stop
        MXP 10:05
        Charleston - Milan | Tue, Nov 3 | American Airlines
        US$764
        21% off
        US$969 US$764
      • MXP 13:20
        16h 23m
        1 stop
        CHS 23:43
        Milan - Charleston | Fri, Oct 2 | American Airlines
        CHS 11:12
        18h 18m
        1 stop
        MXP 11:30
        Charleston - Milan | Fri, Oct 9 | American Airlines
        US$764
        21% off
        US$969 US$764
      • MXP 11:40
        14h 37m
        1 stop
        CHS 20:17
        Milan - Charleston | Tue, Sep 15 | Air France
        CHS 14:12
        13h 13m
        1 stop
        MXP 09:25
        Charleston - Milan | Tue, Sep 22 | Air France
        US$765
        21% off
        US$969 US$765
      • MIL 13:00
        17h 25m
        1 stop
        CHS 14:00
        Milan - Charleston | Fri, Sep 11 | Normal Airline
        CHS 15:00
        6h
        Nonstop
        MIL 16:00
        Charleston - Milan | Sun, Sep 13 | Normal Airline
        More cheap flights
        More cheap flights
      • MXP 13:20
        15h 39m
        1 stop
        CHS 23:59
        Milan - Charleston | Thu, Oct 29 | American Airlines
        US$510 US$1,000
        49% off
        49% off
        US$1,000 US$510
      • MXP 13:20
        15h 39m
        1 stop
        CHS 23:59
        Milan - Charleston | Thu, Oct 29 | British Airways
        US$523 US$1,000
        48% off
        48% off
        US$1,000 US$523
      • MXP 12:05
        33h 30m
        1 stop
        CHS 16:35
        Milan - Charleston | Thu, Oct 29 | Air France
        US$539 US$1,000
        46% off
        46% off
        US$1,000 US$539
      • MXP 12:05
        29h 55m
        1 stop
        CHS 13:00
        Milan - Charleston | Thu, Oct 29 | KLM
        US$539
        46% off
        US$1,000 US$539
      • MXP 14:20
        15h 36m
        1 stop
        CHS 23:56
        Milan - Charleston | Mon, Oct 19 | American Airlines
        US$539
        46% off
        US$1,000 US$539
      • MXP 14:20
        33h 34m
        1 stop
        CHS 17:54
        Milan - Charleston | Mon, Oct 19 | British Airways
        US$550
        45% off
        US$1,000 US$550
      • MXP 14:20
        33h 17m
        1 stop
        CHS 17:37
        Milan - Charleston | Mon, Nov 2 | British Airways
        US$558
        44% off
        US$1,000 US$558
      • MXP 14:20
        15h 36m
        1 stop
        CHS 23:56
        Milan - Charleston | Sat, Oct 17 | British Airways
        US$666
        33% off
        US$1,000 US$666
      • MXP 13:20
        27h 12m
        1 stop
        CHS 10:32
        Milan - Charleston | Sat, Oct 17 | American Airlines
        US$758
        24% off
        US$1,000 US$758
      • MXP 12:00
        34h 23m
        1 stop
        CHS 16:23
        Milan - Charleston | Mon, Nov 2 | KLM
        US$790
        21% off
        US$1,000 US$790
      • MIL 13:00
        17h 25m
        1 stop
        CHS 14:00
        Milan - Charleston | Fri, Sep 11 | Normal Airline
        More cheap flights
        More cheap flights

Which airlines are the most popular for Milan to Charleston flights?

You can choose from 1 airlines that fly from Milan to Charleston, including ITA Airways, American Airlines has lowest fares on this route.
ITA Airways logo ITA Airways
Airlines are determined based on actual purchased flight tickets from Milan to Charleston according to previous 12 months data from Trip.com.

Milan to Charleston Flight Information

The distance between Milan and Charleston is about 7,420.76 km. Based on Trip.com's latest data, travel demand is highest in July. The off-season for travel is November.

Cheapest one-way flight price US$510
Cheapest return ticket price US$742
Cheapest month November
Peak season for travel July
Flight distance 7,420.76 km
Popular airline ITA Airways
Flight statistics for the Milan–Charleston route are based on aggregated booking data from Trip.com over the past 12 months.

Frequently Asked Questions

  • What are the cheapest flights from Milan to Charleston (MIL-CHS)?

    Based on Trip.com data, American Airlines offers one-way fares as low as US$510 on Cheapest nonstop routes (e.g. MXP to CHS on Thu, Oct 29), while American Airlines offers Cheapest nonstop round-trips from US$742 departing on Fri, Sep 25 and returning on Fri, Oct 2.
  • By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Milan to Charleston is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.
  • To find best deals on flights from Milan to Charleston, you can use various tools on Trip.com:
    · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Thu, Oct 29, with one-way flights priced at just US$510.
    · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is American Airlines.
    · Set up price alerts to easily monitor ticket prices without having to check every day.
    · Check Trip.com flight deals and promo codes frequently.
    · Avoid peak season unless you book very early. It seems the peak season for Charleston travel is around July.
    · Get exclusive promo codes for Trip.com app users.
  • The cheapest months to fly from Milan to Charleston is November, when demand for travel is lower.
  • After crunching the numbers on our September flight calendar, it's currently cheapest to fly from Milan to Charleston on September 24, 2026 with American Airlines, with prices starting at US$742.
  • The time difference between Charleston and Milan is 6h.
  • Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.
  • Based on Trip.com data for flights departing in the next 30 days, the average one-way fare from Milan to Charleston is US$1,269. Fares vary by travel date, airline and availability.
  • Enter Milan and Charleston, choose your travel dates and passengers, then compare flights by price, duration and baggage. Select a fare, review the change and cancellation rules, enter traveler details and complete payment to receive your confirmation.

Explore More Popular Flights

Note: Prices shown on this page are the estimated lowest prices found in the last 24 hours and include all taxes and fees.

Book with no extra fees

Prices displayed on this page are all-inclusive (incl. taxes, fuel surcharges, Civil Aviation Development Fund, etc.), and all fees are clearly shown before you pay. Charges for checked baggage, onboard meals, Wi‑Fi, and other optional services are also included where applicable in the flight cards.

Real-time pricing updates

Prices, availability, and travel details on this page have been updated within the last 24 hours, and for many routes are refreshed in real time. The more popular the route, the more accurate and up-to-date the data.

Change & Cancellation Policy

Trip.com shows the change and cancellation rules for each ticket during the booking process, including all related fees and conditions. Please refer to the following scenarios:
Voluntary cancellation/change:
To request a change or cancellation, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and flight segment, and submit your request. Please note that additional charges may apply based on the airline’s fare rules.
Cancellation/change due to a flight schedule change:
If your flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For full details of change and cancellation policies, please refer to the customer support pages.