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Flights from Minneapolis to Knoxville

Cheapest airlines flights from Minneapolis to Knoxville

You can choose from 1 airlines that fly from Minneapolis to Knoxville, including Delta Air Lines, Delta Air Lines has lowest fares on this route.
Delta Air Lines logo Delta Air Lines
Airlines are determined based on actual purchased flight tickets from Minneapolis to Knoxville according to previous 12 months data from Trip.com.

Search for direct flights from Minneapolis to Knoxville in the next 3 months. Based on Trip.com's latest 7-day flight data, one-way direct flights start at US$278, and round-trip direct flights start at US$335.

      • Cheapest nonstop
        MSP 19:45
        2h 16m
        Nonstop
        TYS 23:01
        Minneapolis - Knoxville | Thu, Jul 2 | Delta Air Lines
        TYS 06:45
        2h 33m
        Nonstop
        MSP 08:18
        Knoxville - Minneapolis | Thu, Jul 9 | Delta Air Lines
        US$335 US$363
        8% off
        8% off
        US$363 US$335
      • MSP 19:45
        2h 16m
        Nonstop
        TYS 23:01
        Minneapolis - Knoxville | Thu, Jul 23 | Delta Air Lines
        TYS 06:45
        2h 33m
        Nonstop
        MSP 08:18
        Knoxville - Minneapolis | Mon, Jul 27 | Delta Air Lines
        US$340 US$363
        6% off
        6% off
        US$363 US$340
      • MSP 19:45
        2h 12m
        Nonstop
        TYS 22:57
        Minneapolis - Knoxville | Fri, Jun 26 | Delta Air Lines
        TYS 06:45
        2h 33m
        Nonstop
        MSP 08:18
        Knoxville - Minneapolis | Sun, Jun 28 | Delta Air Lines
        US$341 US$363
        6% off
        6% off
        US$363 US$341
      • MSP 06:10
        7h 10m
        1 stop
        TYS 14:20
        Minneapolis - Knoxville | Sat, Jun 13 | Delta Air Lines
        TYS 06:36
        2h 29m
        Nonstop
        MSP 08:05
        Knoxville - Minneapolis | Wed, Jun 17 | Delta Air Lines
        US$310
        15% off
        US$363 US$310
      • MSP 05:20
        4h 49m
        1 stop
        TYS 11:09
        Minneapolis - Knoxville | Wed, Jun 24 | Delta Air Lines
        TYS 18:42
        2h 35m
        Nonstop
        MSP 20:17
        Knoxville - Minneapolis | Tue, Jun 30 | Delta Air Lines
        US$334
        8% off
        US$363 US$334
      • MSP 18:10
        4h 46m
        1 stop
        TYS 23:56
        Minneapolis - Knoxville | Thu, Jun 25 | Delta Air Lines
        TYS 15:54
        6h 42m
        1 stop
        MSP 21:36
        Knoxville - Minneapolis | Thu, Jul 2 | Delta Air Lines
        US$337
        7% off
        US$363 US$337
      • MSP 19:45
        2h 16m
        Nonstop
        TYS 23:01
        Minneapolis - Knoxville | Wed, Jul 8 | Delta Air Lines
        TYS 05:40
        5h 22m
        1 stop
        MSP 10:02
        Knoxville - Minneapolis | Wed, Jul 15 | Delta Air Lines
        US$339
        7% off
        US$363 US$339
      • MSP 19:45
        2h 16m
        Nonstop
        TYS 23:01
        Minneapolis - Knoxville | Tue, Aug 4 | Delta Air Lines
        TYS 15:54
        6h 40m
        1 stop
        MSP 21:34
        Knoxville - Minneapolis | Sun, Aug 9 | Delta Air Lines
        US$341
        6% off
        US$363 US$341
      • MSP 08:28
        5h 21m
        1 stop
        TYS 14:49
        Minneapolis - Knoxville | Wed, Jul 22 | Delta Air Lines
        TYS 06:37
        2h 33m
        Nonstop
        MSP 08:10
        Knoxville - Minneapolis | Sat, Jul 25 | Delta Air Lines
        US$341
        6% off
        US$363 US$341
      • MSP 07:00
        6h 48m
        1 stop
        TYS 14:48
        Minneapolis - Knoxville | Thu, Aug 6 | Delta Air Lines
        TYS 06:40
        2h 30m
        Nonstop
        MSP 08:10
        Knoxville - Minneapolis | Tue, Aug 11 | Delta Air Lines
        US$341
        6% off
        US$363 US$341
      • MSP 13:00
        17h 25m
        1 stop
        TYS 14:00
        Minneapolis - Knoxville | Wed, Jun 10 | Normal Airline
        TYS 15:00
        6h
        Nonstop
        MSP 16:00
        Knoxville - Minneapolis | Fri, Jun 12 | Normal Airline
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      • Cheapest nonstop
        MSP 19:45
        2h 11m
        Nonstop
        TYS 22:56
        Minneapolis - Knoxville | Thu, Jun 25 | Delta Air Lines
        US$278 US$302
        8% off
        8% off
        US$302 US$278
      • MSP 13:27
        2h 16m
        Nonstop
        TYS 16:43
        Minneapolis - Knoxville | Thu, Jul 23 | Delta Air Lines
        US$283 US$302
        6% off
        6% off
        US$302 US$283
      • MSP 22:15
        20h 22m
        1 stop
        TYS 19:37
        Minneapolis - Knoxville | Fri, Jun 19 | Frontier Airlines
        US$143 US$302
        53% off
        53% off
        US$302 US$143
      • MSP 06:55
        15h 43m
        1 stop
        TYS 23:38
        Minneapolis - Knoxville | Mon, Jun 29 | Sun Country Airlines
        US$183
        39% off
        US$302 US$183
      • MSP 10:18
        8h 19m
        1 stop
        TYS 19:37
        Minneapolis - Knoxville | Mon, Jun 29 | Frontier Airlines
        US$196
        35% off
        US$302 US$196
      • MSP 06:55
        11h 18m
        1 stop
        TYS 19:13
        Minneapolis - Knoxville | Thu, Jun 25 | Frontier Airlines
        US$205
        32% off
        US$302 US$205
      • MSP 08:10
        10h 3m
        1 stop
        TYS 19:13
        Minneapolis - Knoxville | Thu, Jun 25 | Sun Country Airlines
        US$206
        32% off
        US$302 US$206
      • MSP 10:18
        8h 19m
        1 stop
        TYS 19:37
        Minneapolis - Knoxville | Sat, Jul 4 | Frontier Airlines
        US$217
        28% off
        US$302 US$217
      • MSP 21:39
        20h 54m
        1 stop
        TYS 19:33
        Minneapolis - Knoxville | Wed, Jun 17 | Frontier Airlines
        US$232
        23% off
        US$302 US$232
      • MSP 10:18
        8h 19m
        1 stop
        TYS 19:37
        Minneapolis - Knoxville | Mon, Jul 6 | Frontier Airlines
        US$277
        8% off
        US$302 US$277
      • MSP 13:00
        17h 25m
        1 stop
        TYS 14:00
        Minneapolis - Knoxville | Wed, Jun 10 | Normal Airline
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Displayed flight fares from Minneapolis to Knoxville are based on average prices across airlines for the next 3 months, according to the latest Trip.com database.

Minneapolis to Knoxville Flight Details

The distance between Minneapolis and Knoxville is about 1,275.72 km. The average flying time from Minneapolis to Knoxville is around 2 hours 16 minutes. Based on Trip.com's latest data, travel demand is highest in July. The off-season for travel is August.

Cheapest one-way flight priceUS$143
Cheapest return ticket priceUS$310
Cheapest monthAugust
Peak season for travelJuly
Flight distance1,275.72 km
Average flight time2 hours 16 minutes
Popular airlineDelta Air Lines
Flight statistics for the Minneapolis–Knoxville route are based on aggregated booking data from Trip.com over the past 12 months.

Frequently Asked Questions

  • What are the cheapest flights from Minneapolis to Knoxville (MSP-TYS)?

    Based on Trip.com data, Frontier Airlines offers one-way fares as low as US$143 on Cheapest nonstop routes (e.g. MSP to TYS on Fri, Jun 19), while Delta Air Lines offers Cheapest nonstop round-trips from US$310 departing on Sat, Jun 13 and returning on Wed, Jun 17.
  • At the moment, you can catch a nonstop flight from Minneapolis to Knoxville with the following airlines, including: Delta Air Lines Selected airlines are based on historical data collected from flight bookings users made on Trip.com within the last 90 days.
  • It takes about 2 hours 16 minutes to fly from Minneapolis to Knoxville.
  • By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Minneapolis to Knoxville is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.
  • Based on Trip.com data in the past 4 weeks, there is 3 flight per week flying from Minneapolis to Knoxville. You can check the weekly schedule for popular airlines on this route below: Delta Air Lines: S/M/T/W/T/F/S -- DL5527 (20:07)
  • To find best deals on flights from Minneapolis to Knoxville, you can use various tools on Trip.com:
    · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Fri, Jun 19, with one-way flights priced at just US$143.
    · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is Delta Air Lines.
    · Set up price alerts to easily monitor ticket prices without having to check every day.
    · Check Trip.com flight deals and promo codes frequently.
    · Avoid peak season unless you book very early. It seems the peak season for Knoxville travel is around July.
    · Get exclusive promo codes for Trip.com app users.
  • The cheapest months to fly from Minneapolis to Knoxville is August, when demand for travel is lower.
  • After crunching the numbers on our June flight calendar, it's currently cheapest to fly from Minneapolis to Knoxville on June 29, 2026 with Delta Air Lines, with prices starting at US$343.
  • You can land at any one of the following hubs in Knoxville, with Minneapolis-Saint Paul International Airport to Mcghee Tyson Airport (MSP-TYS) is by far the most common option on this route: Mcghee Tyson Airport (TYS).
  • The time difference between Knoxville and Minneapolis is 1h.
  • Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.

Trip.com Airline Insights on Flights from Minneapolis to Knoxville

Which airline operates the most flights from Minneapolis to Knoxville?

Total flights from Minneapolis to Knoxville across all airlines. (Based on Trip.com data from the past month)

Based on Trip.com’s data from the past month, Delta Air Lines/KLM/Air France operates the most frequent flights from Minneapolis to Knoxville, with 8 flights per week.

0
4
8
Delta Air Lines
8
Delta Air Lines
KLM
8
KLM
Air France
8
Air France
Virgin Atlantic
7
Virgin Atlantic
Sun Country Airlines
0
Sun Country Airlines

How many flights fly from Minneapolis to Knoxville daily?

The data is based on the flight numbers for each day of the week from Minneapolis to Knoxville within the Trip.com database over the past month.

Based on the past month's historical data from Trip.com, the number of flights from Minneapolis to Knoxville is the highest on Friday/Saturday and the lowest on Tuesday/Wednesday/Thursday/Sunday.

20
18
16
14
Highest
17
Mon
16
Tue
16
Wed
16
Thu
20
Fri
20
Sat
16
Sun

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Note: Prices shown on this page are the estimated lowest prices found in the last 24 hours and include all taxes and fees.

Book with no extra fees

Prices displayed on this page are all-inclusive (incl. taxes, fuel surcharges, Civil Aviation Development Fund, etc.), and all fees are clearly shown before you pay. Charges for checked baggage, onboard meals, Wi‑Fi, and other optional services are also included where applicable in the flight cards.

Real-time pricing updates

Prices, availability, and travel details on this page have been updated within the last 24 hours, and for many routes are refreshed in real time. The more popular the route, the more accurate and up-to-date the data.

Change & Cancellation Policy

Trip.com shows the change and cancellation rules for each ticket during the booking process, including all related fees and conditions. Please refer to the following scenarios:
Voluntary cancellation/change:
To request a change or cancellation, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and flight segment, and submit your request. Please note that additional charges may apply based on the airline’s fare rules.
Cancellation/change due to a flight schedule change:
If your flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For full details of change and cancellation policies, please refer to the customer support pages.