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Flights from Orlando to Sao Tome Island

We've found these cheap flights for you. You can book one-way or round-trip flight tickets.

      • ORL 13:00
        17h 25m
        1 stop
        TMS 14:00
        Orlando - Sao Tome Island | Sat, May 16 | Normal Airline
        TMS 15:00
        6h
        Nonstop
        ORL 16:00
        Sao Tome Island - Orlando | Mon, May 18 | Normal Airline
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        Search
      • ORL 13:00
        17h 25m
        1 stop
        TMS 14:00
        Orlando - Sao Tome Island | Sat, May 16 | Normal Airline
        TMS 15:00
        6h
        Nonstop
        ORL 16:00
        Sao Tome Island - Orlando | Mon, May 18 | Normal Airline
        Search
        Search
      • ORL 13:00
        17h 25m
        1 stop
        TMS 14:00
        Orlando - Sao Tome Island | Sat, May 16 | Normal Airline
        TMS 15:00
        6h
        Nonstop
        ORL 16:00
        Sao Tome Island - Orlando | Mon, May 18 | Normal Airline
        Search
        Search
      • ORL 13:00
        17h 25m
        1 stop
        TMS 14:00
        Orlando - Sao Tome Island | Sat, May 16 | Normal Airline
        TMS 15:00
        6h
        Nonstop
        ORL 16:00
        Sao Tome Island - Orlando | Mon, May 18 | Normal Airline
        Search
        Search
      • ORL 13:00
        17h 25m
        1 stop
        TMS 14:00
        Orlando - Sao Tome Island | Sat, May 16 | Normal Airline
        TMS 15:00
        6h
        Nonstop
        ORL 16:00
        Sao Tome Island - Orlando | Mon, May 18 | Normal Airline
        Search
        Search
      • ORL 13:00
        17h 25m
        1 stop
        TMS 14:00
        Orlando - Sao Tome Island | Sat, May 16 | Normal Airline
        TMS 15:00
        6h
        Nonstop
        ORL 16:00
        Sao Tome Island - Orlando | Mon, May 18 | Normal Airline
        Search
        Search
      • ORL 13:00
        17h 25m
        1 stop
        TMS 14:00
        Orlando - Sao Tome Island | Sat, May 16 | Normal Airline
        TMS 15:00
        6h
        Nonstop
        ORL 16:00
        Sao Tome Island - Orlando | Mon, May 18 | Normal Airline
        Search
        Search
      • ORL 13:00
        17h 25m
        1 stop
        TMS 14:00
        Orlando - Sao Tome Island | Sat, May 16 | Normal Airline
        TMS 15:00
        6h
        Nonstop
        ORL 16:00
        Sao Tome Island - Orlando | Mon, May 18 | Normal Airline
        Search
        Search
      • ORL 13:00
        17h 25m
        1 stop
        TMS 14:00
        Orlando - Sao Tome Island | Sat, May 16 | Normal Airline
        TMS 15:00
        6h
        Nonstop
        ORL 16:00
        Sao Tome Island - Orlando | Mon, May 18 | Normal Airline
        Search
        Search
      • MCO 21:45
        64h
        2 stops
        TMS 17:45
        Orlando - Sao Tome Island | Sun, Jun 7 | Lufthansa
        US$1,477 US$2,052
        28% off
        28% off
        US$2,052 US$1,477
      • ORL 13:00
        17h 25m
        1 stop
        TMS 14:00
        Orlando - Sao Tome Island | Sat, May 16 | Normal Airline
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Displayed flight fares from Orlando to Sao Tome Island are based on average prices across airlines for the next 3 months, according to the latest Trip.com database.

Frequently Asked Questions

  • When is the best time to book flights from Orlando to Sao Tome Island?

    By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Orlando to Sao Tome Island is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.
  • To find best deals on flights from Orlando to Sao Tome Island, you can use various tools on Trip.com:
    · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Sun, Jun 7, with one-way flights priced at just US$1,477.
    · Set up price alerts to easily monitor ticket prices without having to check every day.
    · Check Trip.com flight deals and promo codes frequently.
    · Avoid peak season unless you book very early. It seems the peak season for Sao Tome Island travel is around April.
    · Get exclusive promo codes for Trip.com app users.
  • The cheapest months to fly from Orlando to Sao Tome Island is October, when demand for travel is lower.
  • The time difference between Sao Tome Island and Orlando is 5h.
  • Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.

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Note: Prices shown on this page are the estimated lowest prices found in the last 24 hours and include all taxes and fees.

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Prices displayed on this page are all-inclusive (incl. taxes, fuel surcharges, Civil Aviation Development Fund, etc.), and all fees are clearly shown before you pay. Charges for checked baggage, onboard meals, Wi‑Fi, and other optional services are also included where applicable in the flight cards.

Real-time pricing updates

Prices, availability, and travel details on this page have been updated within the last 24 hours, and for many routes are refreshed in real time. The more popular the route, the more accurate and up-to-date the data.

Change & Cancellation Policy

Trip.com shows the change and cancellation rules for each ticket during the booking process, including all related fees and conditions. Please refer to the following scenarios:
Voluntary cancellation/change:
To request a change or cancellation, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and flight segment, and submit your request. Please note that additional charges may apply based on the airline’s fare rules.
Cancellation/change due to a flight schedule change:
If your flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For full details of change and cancellation policies, please refer to the customer support pages.