US$107 Cheap Flights from Panama City to Guatemala City

Frequently Asked Questions

• Which airlines offer direct flights from Panama City to Guatemala City?

  At the moment, you can catch a nonstop flight from Panama City to Guatemala City with the following airlines, including: Copa Airlines Selected airlines are based on historical data collected from flight bookings users made on Trip.com within the last 90 days.

• How long is a flight from Panama City to Guatemala City?

  It takes about 2 hours 34 minutes to fly from Panama City to Guatemala City.

• When is the best time to book flights from Panama City to Guatemala City?

  By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Panama City to Guatemala City is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.

• How many flights are there per week from Panama City to Guatemala City?

  Based on Trip.com data in the past 4 weeks, there is 42 flight per week flying from Panama City to Guatemala City. You can check the weekly schedule for popular airlines on this route below: Copa Airlines: S/M/T/W/T/F/S -- CM380 (07:45) Copa Airlines: S/M/T/W/T/F/S -- CM358 (10:25)

• When are flight tickets from Panama City (PTY) to Guatemala City (GUA) the cheapest?

  The cheapest months to fly from Panama City to Guatemala City is November, when demand for travel is lower.

• Which upcoming date is cheapest to fly from Panama City to Guatemala City on?

  After crunching the numbers on our November flight calendar, it's currently cheapest to fly from Panama City to Guatemala City on November 19, 2025 with avianca, with prices starting at US$96.

• Which airports can I fly to for Guatemala City from Panama City?

  You can land at any one of the following hubs in Guatemala City, with Tocumen International Airport to La Aurora International Airport (PTY-GUA) is by far the most common option on this route: La Aurora International Airport (GUA).

• Is there any time difference between Panama City and Guatemala City?

  The time difference between Guatemala City and Panama City is 1h.

• How do I change or cancel my ticket from Panama City to Guatemala City?

  Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.