Cheap Flights from Panama City to Guatemala City from US$151

Frequently Asked Questions

• What are the cheapest flights from Panama City to Guatemala City (PTY-GUA)?

  Based on Trip.com data, Copa Airlines offers one-way fares as low as US$151 on Cheapest nonstop routes (e.g. PTY to GUA on Fri, Nov 6), while avianca offers Cheapest nonstop round-trips from US$240 departing on Sun, Nov 1 and returning on Sat, Nov 7.

• Which airlines offer direct flights from Panama City to Guatemala City?

  At the moment, you can catch a nonstop flight from Panama City to Guatemala City with the following airlines, including: Copa Airlines Selected airlines are based on historical data collected from flight bookings users made on Trip.com within the last 90 days.

• How long is a flight from Panama City to Guatemala City?

  It takes about 2 hours 39 minutes to fly from Panama City to Guatemala City.

• When is the best time to book flights from Panama City to Guatemala City?

  By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Panama City to Guatemala City is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.

• How many flights are there per week from Panama City to Guatemala City?

  Based on Trip.com data in the past 4 weeks, there is 40 flight per week flying from Panama City to Guatemala City. You can check the weekly schedule for popular airlines on this route below: Copa Airlines: S/M/T/W/T/F/S -- CM102 (08:11)

• How can I find the best deals on flights from Panama City to Guatemala City?

  To find best deals on flights from Panama City to Guatemala City, you can use various tools on Trip.com:
  · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Fri, Nov 6, with one-way flights priced at just US$151.
  · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is Copa Airlines.
  · Set up price alerts to easily monitor ticket prices without having to check every day.
  · Check Trip.com flight deals and promo codes frequently.
  · Avoid peak season unless you book very early. It seems the peak season for Guatemala City travel is around January.
  · Get exclusive promo codes for Trip.com app users.

• When are flight tickets from Panama City (PTY) to Guatemala City (GUA) the cheapest?

  The cheapest months to fly from Panama City to Guatemala City is August, when demand for travel is lower.

• Which upcoming date is cheapest to fly from Panama City to Guatemala City on?

  After crunching the numbers on our October flight calendar, it's currently cheapest to fly from Panama City to Guatemala City on October 28, 2026 with Copa Airlines, with prices starting at US$142.

• Which airports fly into Guatemala City from Panama City?

  You can land at any one of the following hubs in Guatemala City: La Aurora International Airport (GUA). Flying from Tocumen International Airport to La Aurora International Airport (PTY-GUA) is by far the most common option on this route.

• Is there any time difference between Panama City and Guatemala City?

  The time difference between Guatemala City and Panama City is 1h.

• How do I change or cancel my ticket from Panama City to Guatemala City?

  Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.

• What is the average cost of a one-way flight from Panama City to Guatemala City?

  Based on Trip.com data for flights departing in the next 30 days, the average one-way fare from Panama City to Guatemala City is US$480. Fares vary by travel date, airline and availability.

• What is the average cost of a round-trip flight from Panama City to Guatemala City?

  Based on Trip.com data for travel in the next 30 days, the average round-trip fare from Panama City to Guatemala City is US$377. The final price depends on the outbound and return dates, airline and fare conditions.

• How do I book flights from Panama City to Guatemala City on Trip.com?

  Enter Panama City and Guatemala City, choose your travel dates and passengers, then compare flights by price, duration and baggage. Select a fare, review the change and cancellation rules, enter traveler details and complete payment to receive your confirmation.