Cheapest airlines flights from Panama City to Quito

You can choose from 2 airlines that fly from Panama City to Quito, including Copa Airlines, avianca, Copa Airlines has lowest fares on this route.
Copa Airlines logo Copa Airlines
avianca logo avianca
Airlines are determined based on actual purchased flight tickets from Panama City to Quito according to previous 12 months data from Trip.com.

Search for direct flights from Panama City to Quito in the next 3 months. Based on Trip.com's latest 7-day flight data, one-way direct flights start at US$378, and round-trip direct flights start at US$275.

Displayed flight fares from Panama City to Quito are based on average prices across airlines for the next 3 months, according to the latest Trip.com database.

Panama City to Quito Flight Details

The distance between Panama City and Quito is about 1,025.46 km. The average flying time from Panama City to Quito is around 2 hours 2 minutes. Based on Trip.com's latest data, travel demand is highest in January. The off-season for travel is October.

Cheapest one-way flight priceUS$119
Cheapest return ticket priceUS$275
Cheapest monthOctober
Peak season for travelJanuary
Flight distance1,025.46 km
Average flight time2 hours 2 minutes
Popular airlineCopa Airlines
Flight statistics for the Panama City–Quito route are based on aggregated booking data from Trip.com over the past 12 months.

Trip.com Price Insights on Flights from Panama City to Quito

Which month has the cheapest one-way flights from Panama City to Quito?

The average price of one-way flights from Panama City to Quito purchased by Trip.com users by month over the past 12 months.

Based on Trip.com’s data, the cheapest month for flights from Panama City to Quito is May, with an average price of US$155; while the month with the highest flight price is usually Dec, with an average price of up to US$420.

US$420
US$288
US$155
US$23
    Cheapest
  • US$165
    Feb
  • US$234
    Mar
  • US$166
    Apr
  • US$155
    May
  • US$178
    Jun
  • US$277
    Jul
  • US$290
    Aug
  • US$181
    Sep
  • US$266
    Oct
  • US$272
    Nov
  • US$420
    Dec
  • US$314
    Jan

What is the cheapest day of the week to fly from Panama City to Quito?

Average weekly flight prices from Panama City to Quito by travel date (Based on Trip.com’s past 12 months of data)

Based on Trip.com’s past 12 months of flight data, the cheapest day to fly from Panama City to Quito is Thu, with average prices lower than on other days. Avoid Mon, as prices are usually highest then.

US$382
US$299
US$216
US$133
    Cheapest
  • US$382
    Mon
  • US$272
    Tue
  • US$241
    Wed
  • US$216
    Thu
  • US$220
    Fri
  • US$224
    Sat
  • US$337
    Sun

Frequently Asked Questions

  • What are the cheapest flights from Panama City to Quito (PTY-UIO)?

    Based on Trip.com data, avianca offers one-way fares as low as US$119 on Cheapest nonstop routes (e.g. PTY to UIO on Thu, Feb 19), while Copa Airlines offers Cheapest nonstop round-trips from US$275 departing on Fri, Feb 20 and returning on Sat, Feb 21.
  • At the moment, you can catch a nonstop flight from Panama City to Quito with the following airlines, including: Copa Airlines Selected airlines are based on historical data collected from flight bookings users made on Trip.com within the last 90 days.
  • It takes about 2 hours 2 minutes to fly from Panama City to Quito.
  • By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Panama City to Quito is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.
  • Based on Trip.com data in the past 4 weeks, there is 31 flight per week flying from Panama City to Quito. You can check the weekly schedule for popular airlines on this route below: Copa Airlines: S/M/T/W/T/F/S -- CM829 (11:01)
  • To find best deals on flights from Panama City to Quito, you can use various tools on Trip.com:
    · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Thu, Feb 19, with one-way flights priced at just US$119.
    · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is Copa Airlines.
    · Set up price alerts to easily monitor ticket prices without having to check every day.
    · Check Trip.com flight deals and promo codes frequently.
    · Avoid peak season unless you book very early. It seems the peak season for Quito travel is around January.
    · Get exclusive promo codes for Trip.com app users.
  • The cheapest months to fly from Panama City to Quito is October, when demand for travel is lower.
  • After crunching the numbers on our February flight calendar, it's currently cheapest to fly from Panama City to Quito on February 20, 2026 with avianca, with prices starting at US$125.
  • You can land at any one of the following hubs in Quito, with Tocumen International Airport to Mariscal Sucre International Airport (PTY-UIO) is by far the most common option on this route: Mariscal Sucre International Airport (UIO).
  • The time difference between Quito and Panama City is 0h.
  • Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.

Trip.com Airline Insights on Flights from Panama City to Quito

Which airline operates the most flights from Panama City to Quito?

Total flights from Panama City to Quito across all airlines. (Based on Trip.com data from the past month)

Based on Trip.com’s data from the past month, Copa Airlines operates the most frequent flights from Panama City to Quito, with 35 flights per week.

0
0
18
35
Copa Airlines
35
Copa Airlines
KLM
15
KLM
Air France
8
Air France
Turkish Airlines
8
Turkish Airlines
Tampa Cargo
0
Tampa Cargo

How many flights fly from Panama City to Quito daily?

The data is based on the flight numbers for each day of the week from Panama City to Quito within the Trip.com database over the past month.

Based on the past month's historical data from Trip.com, the number of flights from Panama City to Quito is the highest on Friday and the lowest on Tuesday.

42
38
34
30
Highest
35
Mon
34
Tue
34
Wed
34
Thu
42
Fri
42
Sat
38
Sun