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Flights from Rome to Santa Maria

Search cheap flights from Rome to Santa Maria in the next 3 months. Based on Trip.com's latest 7-day data, one-way fares start at US$342, and round-trip tickets start at US$562.

      • FCO 20:00
        22h 30m
        1 stop
        SMA 16:30
        Rome - Santa Maria | Mon, May 18 | TAP Air Portugal
        SMA 17:20
        15h
        1 stop
        FCO 10:20
        Santa Maria - Rome | Tue, May 26 | TAP Air Portugal
        US$562 US$1,097
        49% off
        49% off
        US$1,097 US$562
      • FCO 05:55
        12h 35m
        1 stop
        SMA 16:30
        Rome - Santa Maria | Tue, May 19 | TAP Air Portugal
        SMA 17:20
        28h 55m
        1 stop
        FCO 00:15
        Santa Maria - Rome | Fri, May 22 | TAP Air Portugal
        US$565 US$1,097
        48% off
        48% off
        US$1,097 US$565
      • FCO 17:40
        24h 50m
        1 stop
        SMA 16:30
        Rome - Santa Maria | Thu, Jun 11 | TAP Air Portugal
        SMA 17:20
        15h
        1 stop
        FCO 10:20
        Santa Maria - Rome | Fri, Jun 19 | TAP Air Portugal
        US$662 US$1,097
        40% off
        40% off
        US$1,097 US$662
      • FCO 20:00
        22h 30m
        1 stop
        SMA 16:30
        Rome - Santa Maria | Thu, May 28 | TAP Air Portugal
        SMA 17:20
        28h 55m
        1 stop
        FCO 00:15
        Santa Maria - Rome | Fri, Jun 5 | TAP Air Portugal
        US$711
        35% off
        US$1,097 US$711
      • FCO 17:45
        24h 45m
        1 stop
        SMA 16:30
        Rome - Santa Maria | Mon, May 18 | SATA International
        SMA 17:20
        29h 5m
        1 stop
        FCO 00:25
        Santa Maria - Rome | Tue, May 26 | SATA International
        US$712
        35% off
        US$1,097 US$712
      • FCO 05:55
        12h 35m
        1 stop
        SMA 16:30
        Rome - Santa Maria | Tue, May 26 | TAP Air Portugal
        SMA 17:20
        15h
        1 stop
        FCO 10:20
        Santa Maria - Rome | Fri, May 29 | TAP Air Portugal
        US$750
        32% off
        US$1,097 US$750
      • FCO 17:40
        24h 50m
        1 stop
        SMA 16:30
        Rome - Santa Maria | Thu, Jun 11 | SATA International
        SMA 17:20
        15h
        1 stop
        FCO 10:20
        Santa Maria - Rome | Fri, Jun 19 | SATA International
        US$832
        24% off
        US$1,097 US$832
      • FCO 05:55
        12h 35m
        1 stop
        SMA 16:30
        Rome - Santa Maria | Tue, Jun 9 | TAP Air Portugal
        SMA 17:20
        29h 5m
        1 stop
        FCO 00:25
        Santa Maria - Rome | Tue, Jun 16 | TAP Air Portugal
        US$861
        22% off
        US$1,097 US$861
      • FCO 20:00
        22h 30m
        1 stop
        SMA 16:30
        Rome - Santa Maria | Thu, May 28 | SATA International
        SMA 17:20
        28h 55m
        1 stop
        FCO 00:15
        Santa Maria - Rome | Fri, Jun 5 | TAP Air Portugal
        US$866
        21% off
        US$1,097 US$866
      • ROM 13:00
        17h 25m
        1 stop
        SMA 14:00
        Rome - Santa Maria | Tue, May 19 | Normal Airline
        SMA 15:00
        6h
        Nonstop
        ROM 16:00
        Santa Maria - Rome | Thu, May 21 | Normal Airline
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      • FCO 20:00
        22h 30m
        1 stop
        SMA 16:30
        Rome - Santa Maria | Mon, May 18 | TAP Air Portugal
        US$342 US$873
        61% off
        61% off
        US$873 US$342
      • FCO 11:10
        7h 20m
        1 stop
        SMA 16:30
        Rome - Santa Maria | Tue, May 19 | TAP Air Portugal
        US$342 US$873
        61% off
        61% off
        US$873 US$342
      • FCO 17:45
        24h 45m
        1 stop
        SMA 16:30
        Rome - Santa Maria | Mon, Jul 13 | SATA International
        US$399 US$873
        54% off
        54% off
        US$873 US$399
      • FCO 17:45
        24h 45m
        1 stop
        SMA 16:30
        Rome - Santa Maria | Mon, May 18 | SATA International
        US$424
        51% off
        US$873 US$424
      • FCO 20:00
        22h 30m
        1 stop
        SMA 16:30
        Rome - Santa Maria | Mon, Jul 13 | TAP Air Portugal
        US$430
        51% off
        US$873 US$430
      • FCO 05:55
        12h 35m
        1 stop
        SMA 16:30
        Rome - Santa Maria | Fri, Jun 12 | ITA Airways
        US$689
        21% off
        US$873 US$689
      • ROM 13:00
        17h 25m
        1 stop
        SMA 14:00
        Rome - Santa Maria | Tue, May 19 | Normal Airline
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Displayed flight fares from Rome to Santa Maria are based on average prices across airlines for the next 3 months, according to the latest Trip.com database.

Frequently Asked Questions

  • What are the cheapest flights from Rome to Santa Maria (ROM-SMA)?

    Based on Trip.com data, TAP Air Portugal offers one-way fares as low as US$342 on Cheapest nonstop routes (e.g. FCO to SMA on Mon, May 18), while TAP Air Portugal offers Cheapest nonstop round-trips from US$562 departing on Mon, May 18 and returning on Tue, May 26.
  • By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Rome to Santa Maria is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.
  • To find best deals on flights from Rome to Santa Maria, you can use various tools on Trip.com:
    · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Mon, May 18, with one-way flights priced at just US$342.
    · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is TAP Air Portugal.
    · Set up price alerts to easily monitor ticket prices without having to check every day.
    · Check Trip.com flight deals and promo codes frequently.
    · Avoid peak season unless you book very early. It seems the peak season for Santa Maria travel is around September.
    · Get exclusive promo codes for Trip.com app users.
  • The cheapest months to fly from Rome to Santa Maria is November, when demand for travel is lower.
  • After crunching the numbers on our May flight calendar, it's currently cheapest to fly from Rome to Santa Maria on May 30, 2026 with TAP Air Portugal, with prices starting at US$662.
  • The time difference between Santa Maria and Rome is 2h.
  • Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.

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Note: Prices shown on this page are the estimated lowest prices found in the last 24 hours and include all taxes and fees.

Book with no extra fees

Prices displayed on this page are all-inclusive (incl. taxes, fuel surcharges, Civil Aviation Development Fund, etc.), and all fees are clearly shown before you pay. Charges for checked baggage, onboard meals, Wi‑Fi, and other optional services are also included where applicable in the flight cards.

Real-time pricing updates

Prices, availability, and travel details on this page have been updated within the last 24 hours, and for many routes are refreshed in real time. The more popular the route, the more accurate and up-to-date the data.

Change & Cancellation Policy

Trip.com shows the change and cancellation rules for each ticket during the booking process, including all related fees and conditions. Please refer to the following scenarios:
Voluntary cancellation/change:
To request a change or cancellation, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and flight segment, and submit your request. Please note that additional charges may apply based on the airline’s fare rules.
Cancellation/change due to a flight schedule change:
If your flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For full details of change and cancellation policies, please refer to the customer support pages.