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Cheap Flights from Saint Louis to San Diego

  • Saint Louis San Diego

    Thu, Apr 9 - Sun, Apr 12

    From US$177.68
  • Saint Louis San Diego

    Fri, May 1 - Mon, May 4

    From US$180.78
  • Saint Louis San Diego

    Thu, Jun 11 - Sun, Jun 14

    From US$192.48
  • Saint Louis San Diego

    Thu, Apr 9 - Sun, Apr 12

    From US$230.70
  • Saint Louis San Diego

    Thu, Apr 9 - Sun, Apr 12

    From US$198.69
  • Saint Louis San Diego

    Thu, Jun 11 - Sun, Jun 14

    From US$236.34

Prices shown are for 1 adult ticket including taxes & fees.(As ticket fares can change frequently, these advertised prices are for reference only. The actual prices will be shown at time of booking.)

Saint Louis to San Diego Flight Information

Below are some common questions asked about this flight route:

When can I book the cheapest flight from Saint Louis to San Diego?

Airlines adjust prices for plane tickets based on the day and time that you book your flight. After analyzing data from all airlines, we have discovered that the best days to book flights from Saint Louis to San Diego are Tuesdays, Wednesdays, and Saturdays.

What are the airlines flying from Saint Louis to San Diego?

Airlines flying from Saint Louis to San Diego include Alaska Airlines.

What is the most popular airline for non-stop flights from Saint Louis to San Diego?

provides of the non-stop flights between Saint Louis and San Diego.

How many airports are there in San Diego?

There are 2 airports in San Diego - San Diego International Airport,McClellan-Palomar Airport.

Average duration of direct flights: 3h48m
Airports at destination:
Flight route:
Price starting from:

Saint Louis to San Diego Flight Schedule

Flight info. Departure
Arrival
Route Weekly Schedule
17:00 STL 18:50 SAN
Saint Louis to San Diego SMTWTFS Search
17:25 STL 19:15 SAN
Saint Louis to San Diego SMTWTFS Search
16:45 STL 18:50 SAN
Saint Louis to San Diego SMTWTFS Search

Roundtrip vs One-Way Flights from Saint Louis to San Diego

There is usually no major price difference between buying a roundtrip flight versus a one-way flight. Increased flexibility is the main benefit when it comes to buying a one-way flight from Saint Louis to San Diego. However, booking a roundtrip flight is a simpler process. You can compare roundtrip and one-way flights by using our flight comparison tool.

Travel from Saint Louis to San Diego

San Diego attracts thousands of visitors every year for both business and pleasure. Planning a trip from Saint Louis to San Diego is easy when you use Trip.com to help you make travel arrangements. With Trip.com, you can search for available flights and hotel rooms, and then make your booking quickly and easily online.

A Trip to Remember

Make your journey from Saint Louis to San Diego a trip to remember when you use Trip.com to review city attractions before you arrive. With a preview of what's available at your destination, you can make any necessary reservations in advance for the best travel experience possible.