Cheapest airlines flights from Santa Cruz to Mexico City
Copa Airlines Find Cheapest Flights from Santa Cruz to Mexico City
Search cheap flights from Santa Cruz to Mexico City in the next 3 months. Based on Trip.com's latest 7-day data, one-way fares start at US$323, and round-trip tickets start at US$556.
- Round-trip
- One way
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VVI 03:3521h 25m1 stopMEX 23:00Santa Cruz - Mexico City | Thu, May 28 | avianca
MEX 04:5519h 35m1 stopVVI 02:30Mexico City - Santa Cruz | Thu, Jun 4 | aviancaUS$556 US$79130% off30% offUS$791 US$556-
VVI 03:3510h 35m1 stopMEX 12:10Santa Cruz - Mexico City | Mon, May 4 | avianca
MEX 14:0010h 30m1 stopVVI 02:30Mexico City - Santa Cruz | Mon, May 11 | aviancaUS$561 US$79128% off28% offUS$791 US$561 -
VVI 03:3521h 25m1 stopMEX 23:00Santa Cruz - Mexico City | Sat, Apr 18 | avianca
MEX 00:4023h 50m1 stopVVI 02:30Mexico City - Santa Cruz | Tue, Apr 21 | aviancaUS$565 US$79128% off28% offUS$791 US$565 -
VVI 03:3510h 35m1 stopMEX 12:10Santa Cruz - Mexico City | Wed, May 27 | avianca
MEX 00:4023h 50m1 stopVVI 02:30Mexico City - Santa Cruz | Sat, May 30 | aviancaUS$57028% offUS$791 US$570 -
VVI 03:3525h 30m1 stopMEX 03:05Santa Cruz - Mexico City | Thu, Apr 30 | avianca
MEX 00:4023h 50m1 stopVVI 02:30Mexico City - Santa Cruz | Mon, May 4 | aviancaUS$57328% offUS$791 US$573 -
VVI 01:1225h 3m1 stopMEX 00:15Santa Cruz - Mexico City | Thu, May 28 | Copa Airlines
MEX 09:5010h 48m1 stopVVI 22:38Mexico City - Santa Cruz | Thu, Jun 4 | Copa AirlinesUS$57427% offUS$791 US$574 -
VVI 03:3516h 30m1 stopMEX 18:05Santa Cruz - Mexico City | Wed, May 20 | avianca
MEX 23:2025h 10m1 stopVVI 02:30Mexico City - Santa Cruz | Wed, May 27 | aviancaUS$57527% offUS$791 US$575 -
VVI 03:3521h 25m1 stopMEX 23:00Santa Cruz - Mexico City | Fri, May 1 | avianca
MEX 04:5519h 35m1 stopVVI 02:30Mexico City - Santa Cruz | Mon, May 4 | aviancaUS$58027% offUS$791 US$580 -
VVI 03:3510h 35m1 stopMEX 12:10Santa Cruz - Mexico City | Fri, May 8 | avianca
MEX 14:0010h 30m1 stopVVI 02:30Mexico City - Santa Cruz | Tue, May 12 | aviancaUS$58226% offUS$791 US$582 -
VVI 03:3516h 30m1 stopMEX 18:05Santa Cruz - Mexico City | Mon, May 25 | avianca
MEX 00:4023h 50m1 stopVVI 02:30Mexico City - Santa Cruz | Mon, Jun 1 | aviancaUS$58526% offUS$791 US$585 -
SRZ 13:0017h 25m1 stopMEX Invalid DateSanta Cruz - Mexico City | Sun, Apr 19 | Normal Airline
MEX 15:006hNonstopSRZ 16:00Mexico City - Santa Cruz | Tue, Apr 21 | Normal AirlineFind more flightsFind more flights
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VVI 03:3510h 35m1 stopMEX 12:10Santa Cruz - Mexico City | Fri, Apr 24 | aviancaUS$323 US$53440% off40% offUS$534 US$323 -
VVI 03:3516h 30m1 stopMEX 18:05Santa Cruz - Mexico City | Fri, May 1 | aviancaUS$324 US$53439% off39% offUS$534 US$324 -
VVI 03:3521h 25m1 stopMEX 23:00Santa Cruz - Mexico City | Tue, May 26 | aviancaUS$325 US$53439% off39% offUS$534 US$325 -
VVI 03:3516h 30m1 stopMEX 18:05Santa Cruz - Mexico City | Wed, May 13 | aviancaUS$32539% offUS$534 US$325 -
VVI 03:3525h 30m1 stopMEX 03:05Santa Cruz - Mexico City | Mon, May 18 | aviancaUS$32539% offUS$534 US$325 -
VVI 03:3521h 25m1 stopMEX 23:00Santa Cruz - Mexico City | Fri, May 22 | aviancaUS$32539% offUS$534 US$325 -
VVI 03:3510h 35m1 stopMEX 12:10Santa Cruz - Mexico City | Tue, May 19 | aviancaUS$32539% offUS$534 US$325 -
VVI 03:3521h 25m1 stopMEX 23:00Santa Cruz - Mexico City | Wed, Apr 29 | aviancaUS$32539% offUS$534 US$325 -
VVI 03:3516h 30m1 stopMEX 18:05Santa Cruz - Mexico City | Mon, May 25 | aviancaUS$32539% offUS$534 US$325 -
VVI 03:3525h 30m1 stopMEX 03:05Santa Cruz - Mexico City | Thu, Apr 23 | aviancaUS$39526% offUS$534 US$395 -
SRZ 13:0017h 25m1 stopMEX Invalid DateSanta Cruz - Mexico City | Sun, Apr 19 | Normal AirlineFind more flightsFind more flights
Displayed flight fares from Santa Cruz to Mexico City are based on average prices across airlines for the next 3 months, according to the latest Trip.com database.
Santa Cruz to Mexico City Flight Details
The distance between Santa Cruz and Mexico City is about 5,702.49 km. Based on Trip.com's latest data, travel demand is highest in January. The off-season for travel is September.
| Cheapest one-way flight price | US$323 |
|---|---|
| Cheapest return ticket price | US$556 |
| Cheapest month | September |
| Peak season for travel | January |
| Flight distance | 5,702.49 km |
| Popular airline | Copa Airlines |
Frequently Asked Questions
What are the cheapest flights from Santa Cruz to Mexico City (SRZ-MEX)?
Based on Trip.com data, avianca offers one-way fares as low as US$323 on Cheapest nonstop routes (e.g. VVI to MEX on Fri, Apr 24), while avianca offers Cheapest nonstop round-trips from US$556 departing on Thu, May 28 and returning on Thu, Jun 4.Which airlines offer flights from Santa Cruz to Mexico City?
At the moment, several airlines serve connecting flights from Santa Cruz to Mexico City, including: Copa Airlines Selected airlines are based on historical data collected from flight bookings made by users on Trip.com within the last 90 days.When is the best time to book flights from Santa Cruz to Mexico City?
By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Santa Cruz to Mexico City is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.How can I find the best deals on flights from Santa Cruz to Mexico City?
To find best deals on flights from Santa Cruz to Mexico City, you can use various tools on Trip.com:
· Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Fri, Apr 24, with one-way flights priced at just US$323.
· Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is avianca.
· Set up price alerts to easily monitor ticket prices without having to check every day.
· Check Trip.com flight deals and promo codes frequently.
· Avoid peak season unless you book very early. It seems the peak season for Mexico City travel is around January.
· Get exclusive promo codes for Trip.com app users.When are flight tickets from Santa Cruz (SRZ) to Mexico City (MEX) the cheapest?
The cheapest months to fly from Santa Cruz to Mexico City is September, when demand for travel is lower.Which upcoming date is cheapest to fly from Santa Cruz to Mexico City on?
After crunching the numbers on our April flight calendar, it's currently cheapest to fly from Santa Cruz to Mexico City on April 24, 2026 with avianca, with prices starting at US$323.Which airports can I fly to for Mexico City from Santa Cruz?
You can land at any one of the following hubs in Mexico City, with Viru Viru International Airport to Mexico City International Airport (VVI-MEX) is by far the most common option on this route: Mexico City International Airport (MEX) Felipe Ángeles International Airport (NLU) Lic. Adolfo López Mateos International Airport (TLC).Is there any time difference between Santa Cruz and Mexico City?
The time difference between Mexico City and Santa Cruz is 2h.How do I change or cancel my ticket from Santa Cruz to Mexico City?
Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.
Trip.com Airline Insights on Flights from Santa Cruz to Mexico City
Which airline offers the cheapest direct flights from Santa Cruz to Mexico City?
Based on Trip.com’s data from the past 12 months, avianca provides the lowest-priced direct flights from Santa Cruz to Mexico City, with fares starting at US$509.
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Note: Prices shown on this page are the estimated lowest prices found in the last 24 hours and include all taxes and fees.