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Flights from Santiago to Cusco

Hi, I've summed up all the key info for Santiago to Cusco flights

Cheapest one-way

US$ 102
Sky Airline Mon, Oct 5

44% below next 30d avg. (US$182)

Cheapest round-trip

US$ 206
Sky Airline Thu, Oct 1

39% below next 30d avg. (US$340)

When to fly

November Cheapest month
July Peak month

Fastest flight

3h 30m 10m faster than avg. (3h 40m)

Recommended airlines

With a lowest one-way fare of US$102 , travelers can expect an average price of US$182 for upcoming trips, while round-trip tickets start at US$206 . Flights typically take around 3h 40m , but the fastest nonstop option completes the journey in just 3h 30m minutes. There are 6 flights weekly on this route. You can land at any one of the following hubs in Cusco: Alejandro Velasco Astete International Airport (CUZ) . Flying from Arturo Merino Benitez International Airport to Alejandro Velasco Astete International Airport (SCL-CUZ) is by far the most common option on this route. To secure the best rates, booking 40 days in advance is recommended, and the cheapest travel days are Tuesday, Wednesday, and Saturday .

Updated 3d ago · This content is an AI-powered summary based on Trip.com data. Prices and availability are subject to change. Please refer to actual prices, availability, and travel conditions.

Explore the cheapest one-way and round-trip flights from Santiago to Cusco over the next 90 days, with one-way fares from US$102 and round-trip from US$206. Based on Trip.com's latest 7-day flight data.

      • Cheapest nonstop
        SCL 07:10
        3h 30m
        Nonstop
        CUZ 08:40
        Santiago - Cusco | Tue, Sep 29 | LATAM Airlines
        CUZ 09:40
        3h 20m
        Nonstop
        SCL 15:00
        Cusco - Santiago | Sun, Oct 4 | LATAM Airlines
        US$235 US$275
        15% off
        15% off
        US$275 US$235
      • SCL 07:10
        3h 30m
        Nonstop
        CUZ 08:40
        Santiago - Cusco | Sun, Sep 27 | LATAM Airlines
        CUZ 09:40
        3h 20m
        Nonstop
        SCL 15:00
        Cusco - Santiago | Wed, Sep 30 | LATAM Airlines
        US$238 US$275
        13% off
        13% off
        US$275 US$238
      • SCL 07:10
        3h 30m
        Nonstop
        CUZ 08:40
        Santiago - Cusco | Tue, Oct 6 | LATAM Airlines
        CUZ 09:40
        3h 20m
        Nonstop
        SCL 15:00
        Cusco - Santiago | Fri, Oct 9 | LATAM Airlines
        US$246 US$275
        11% off
        11% off
        US$275 US$246
      • SCL 13:33
        7h 37m
        1 stop
        CUZ 19:10
        Santiago - Cusco | Thu, Oct 1 | Sky Airline
        CUZ 21:15
        13h 26m
        1 stop
        SCL 12:41
        Cusco - Santiago | Sat, Oct 3 | Sky Airline
        US$206
        25% off
        US$275 US$206
      • SCL 06:00
        8h 45m
        1 stop
        CUZ 12:45
        Santiago - Cusco | Mon, Sep 28 | Sky Airline
        CUZ 06:55
        13h 41m
        1 stop
        SCL 22:36
        Cusco - Santiago | Mon, Oct 5 | Sky Airline
        US$207
        25% off
        US$275 US$207
      • SCL 06:07
        6h 53m
        1 stop
        CUZ 11:00
        Santiago - Cusco | Mon, Sep 28 | JetSMART Airlines
        CUZ 06:55
        13h 41m
        1 stop
        SCL 22:36
        Cusco - Santiago | Mon, Oct 5 | Sky Airline
        US$230
        16% off
        US$275 US$230
      • SCL 07:10
        3h 30m
        Nonstop
        CUZ 08:40
        Santiago - Cusco | Sat, Sep 26 | LATAM Airlines
        CUZ 09:45
        6h 40m
        1 stop
        SCL 18:25
        Cusco - Santiago | Tue, Sep 29 | LATAM Airlines
        US$251
        9% off
        US$275 US$251
      • SCL 17:50
        9h 10m
        1 stop
        CUZ 01:00
        Santiago - Cusco | Thu, Oct 1 | LATAM Airlines
        CUZ 09:40
        3h 20m
        Nonstop
        SCL 15:00
        Cusco - Santiago | Sat, Oct 3 | LATAM Airlines
        US$251
        9% off
        US$275 US$251
      • SCL 06:17
        7h 38m
        1 stop
        CUZ 11:55
        Santiago - Cusco | Thu, Oct 1 | JetSMART Airlines
        CUZ 12:10
        8h 26m
        1 stop
        SCL 22:36
        Cusco - Santiago | Mon, Oct 5 | Sky Airline
        US$255
        7% off
        US$275 US$255
      • SCL 21:20
        10h 50m
        1 stop
        CUZ 06:10
        Santiago - Cusco | Tue, Sep 29 | Sky Airline
        CUZ 17:35
        9h 51m
        1 stop
        SCL 05:26
        Cusco - Santiago | Mon, Oct 5 | Sky Airline
        US$255
        7% off
        US$275 US$255
      • SCL 13:00
        17h 25m
        1 stop
        CUZ 14:00
        Santiago - Cusco | Mon, Sep 14 | Normal Airline
        CUZ 15:00
        6h
        Nonstop
        SCL 16:00
        Cusco - Santiago | Wed, Sep 16 | Normal Airline
        More cheap flights
        More cheap flights
      • Cheapest nonstop
        SCL 07:10
        3h 30m
        Nonstop
        CUZ 08:40
        Santiago - Cusco | Sat, Sep 19 | LATAM Airlines
        US$120 US$130
        8% off
        8% off
        US$130 US$120
      • SCL 06:53
        15h 52m
        1 stop
        CUZ 20:45
        Santiago - Cusco | Mon, Oct 5 | Sky Airline
        US$102 US$130
        22% off
        22% off
        US$130 US$102
      • SCL 21:20
        10h 50m
        1 stop
        CUZ 06:10
        Santiago - Cusco | Sat, Sep 19 | Sky Airline
        US$112 US$130
        14% off
        14% off
        US$130 US$112
      • SCL 06:53
        14h 17m
        1 stop
        CUZ 19:10
        Santiago - Cusco | Wed, Oct 14 | Sky Airline
        US$112
        14% off
        US$130 US$112
      • SCL 06:53
        15h 42m
        1 stop
        CUZ 20:35
        Santiago - Cusco | Sun, Oct 4 | Sky Airline
        US$115
        12% off
        US$130 US$115
      • SCL 00:18
        11h 47m
        1 stop
        CUZ 10:05
        Santiago - Cusco | Thu, Oct 1 | Sky Airline
        US$115
        12% off
        US$130 US$115
      • SCL 07:00
        14h 10m
        1 stop
        CUZ 19:10
        Santiago - Cusco | Wed, Nov 4 | Sky Airline
        US$116
        11% off
        US$130 US$116
      • SCL 05:41
        13h 29m
        1 stop
        CUZ 17:10
        Santiago - Cusco | Tue, Sep 22 | JetSMART Airlines
        US$117
        10% off
        US$130 US$117
      • SCL 21:20
        10h 50m
        1 stop
        CUZ 06:10
        Santiago - Cusco | Sat, Sep 26 | Sky Airline
        US$118
        9% off
        US$130 US$118
      • SCL 06:00
        12h 55m
        1 stop
        CUZ 16:55
        Santiago - Cusco | Tue, Sep 22 | Sky Airline
        US$119
        8% off
        US$130 US$119
      • SCL 13:00
        17h 25m
        1 stop
        CUZ 14:00
        Santiago - Cusco | Mon, Sep 14 | Normal Airline
        More cheap flights
        More cheap flights

Flight.News
Flights from Santiago to Cusco operate an average of 1 times per day over the past 7 days, with a 14.3% on-time departure rate and a 100.0% on-time arrival rate.

Which airlines are the most popular for Santiago to Cusco flights?

You can choose from 1 airlines that fly from Santiago to Cusco, including LATAM Airlines, Sky Airline has lowest fares on this route.
LATAM Airlines logo LATAM Airlines
Airlines are determined based on actual purchased flight tickets from Santiago to Cusco according to previous 12 months data from Trip.com.

Santiago to Cusco Flight Information

The distance between Santiago and Cusco is about 2,211.1 km. The average flying time from Santiago to Cusco is around 3 hours 40 minutes. Based on Trip.com's latest data, travel demand is highest in July. The off-season for travel is November.

Cheapest one-way flight price US$102
Cheapest return ticket price US$206
Cheapest month November
Peak season for travel July
Flight distance 2,211.1 km
Average flight time 3 hours 40 minutes
Popular airline LATAM Airlines
Frequency ～4/week
Flight statistics for the Santiago–Cusco route are based on aggregated booking data from Trip.com over the past 12 months.

Trip.com Price Trends on Flights from Santiago to Cusco

Which month has the cheapest one-way flights from Santiago to Cusco?

Average monthly one-way flight prices from Santiago to Cusco, based on bookings made by Trip.com users over the past 12 months.

Based on Trip.com’s data, the cheapest month for flights from Santiago to Cusco is November, with an average price of US$188; while the month with the highest flight price is usually January, with an average price of up to US$294.

US$294
US$241
US$188
US$135
    Cheapest
  • US$203
    Sep
  • US$205
    Oct
  • US$188
    Nov
  • US$268
    Dec
  • US$294
    Jan
  • US$235
    Feb
  • US$217
    Mar
  • US$218
    Apr
  • US$218
    May
  • US$251
    Jun
  • US$219
    Jul
  • US$246
    Aug

Frequently Asked Questions

  • What are the cheapest flights from Santiago to Cusco (SCL-CUZ)?

    Based on Trip.com data, Sky Airline offers one-way fares as low as US$102 on Cheapest nonstop routes (e.g. SCL to CUZ on Mon, Oct 5), while Sky Airline offers Cheapest nonstop round-trips from US$206 departing on Thu, Oct 1 and returning on Sat, Oct 3.
  • At the moment, you can catch a nonstop flight from Santiago to Cusco with the following airlines, including: LATAM Airlines Selected airlines are based on historical data collected from flight bookings users made on Trip.com within the last 90 days.
  • It takes about 3 hours 40 minutes to fly from Santiago to Cusco.
  • By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Santiago to Cusco is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.
  • Based on Trip.com data in the past 4 weeks, there is 6 flight per week flying from Santiago to Cusco. You can check the weekly schedule for popular airlines on this route below: LATAM Airlines: S/M/T/W/T/F/S -- LA2367 (07:33)
  • To find best deals on flights from Santiago to Cusco, you can use various tools on Trip.com:
    · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Mon, Oct 5, with one-way flights priced at just US$102.
    · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is LATAM Airlines.
    · Set up price alerts to easily monitor ticket prices without having to check every day.
    · Check Trip.com flight deals and promo codes frequently.
    · Avoid peak season unless you book very early. It seems the peak season for Cusco travel is around July.
    · Get exclusive promo codes for Trip.com app users.
  • The cheapest months to fly from Santiago to Cusco is November, when demand for travel is lower.
  • After crunching the numbers on our September flight calendar, it's currently cheapest to fly from Santiago to Cusco on September 20, 2026 with Sky Airline, with prices starting at US$112.
  • You can land at any one of the following hubs in Cusco: Alejandro Velasco Astete International Airport (CUZ). Flying from Arturo Merino Benitez International Airport to Alejandro Velasco Astete International Airport (SCL-CUZ) is by far the most common option on this route.
  • The time difference between Cusco and Santiago is 1h.
  • Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.
  • Based on Trip.com data for flights departing in the next 30 days, the average one-way fare from Santiago to Cusco is US$182. Fares vary by travel date, airline and availability.
  • Based on Trip.com data for travel in the next 30 days, the average round-trip fare from Santiago to Cusco is US$340. The final price depends on the outbound and return dates, airline and fare conditions.
  • Enter Santiago and Cusco, choose your travel dates and passengers, then compare flights by price, duration and baggage. Select a fare, review the change and cancellation rules, enter traveler details and complete payment to receive your confirmation.
  • Sky Airlineare the most popular budget airlines flying from Santiago to Cusco. Check baggage, seat and payment fees before comparing the final price.

Trip.com Airline Insights on Flights from Santiago to Cusco

Which airline offers the cheapest direct flights from Santiago to Cusco?

Data is based on the average price of all nonstop flights from Santiago to Cusco on Trip.com over the past 12 months.

Based on Trip.com’s data from the past 12 months, Sky Airline provides the lowest-priced direct flights from Santiago to Cusco, with fares starting at US$184.

US$147
US$184
US$221
US$258
US$295
Sky Airline
US$184
Sky Airline
LATAM Airlines
US$267
LATAM Airlines
JetSMART Airlines
US$295
JetSMART Airlines

How many flights fly from Santiago to Cusco daily?

The data is based on the flight numbers for each day of the week from Santiago to Cusco within the Trip.com database over the past month.

Based on the past month's historical data from Trip.com, the number of flights from Santiago to Cusco is the highest on Friday/Saturday/Sunday and the lowest on Monday/Tuesday/Wednesday/Thursday.

5
4
Highest
4
Mon
4
Tue
4
Wed
4
Thu
5
Fri
5
Sat
5
Sun

Explore More Popular Flights

Note: Prices shown on this page are the estimated lowest prices found in the last 24 hours and include all taxes and fees.

Book with no extra fees

Prices displayed on this page are all-inclusive (incl. taxes, fuel surcharges, Civil Aviation Development Fund, etc.), and all fees are clearly shown before you pay. Charges for checked baggage, onboard meals, Wi‑Fi, and other optional services are also included where applicable in the flight cards.

Real-time pricing updates

Prices, availability, and travel details on this page have been updated within the last 24 hours, and for many routes are refreshed in real time. The more popular the route, the more accurate and up-to-date the data.

Change & Cancellation Policy

Trip.com shows the change and cancellation rules for each ticket during the booking process, including all related fees and conditions. Please refer to the following scenarios:
Voluntary cancellation/change:
To request a change or cancellation, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and flight segment, and submit your request. Please note that additional charges may apply based on the airline’s fare rules.
Cancellation/change due to a flight schedule change:
If your flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For full details of change and cancellation policies, please refer to the customer support pages.