Cheapest airlines flights from Santiago to Mendoza

You can choose from 3 airlines that fly from Santiago to Mendoza, including Sky Airline, JetSMART Airlines, and LATAM Airlines. Sky Airline has lowest fares on this route.
Sky Airline logo Sky Airline
JetSMART Airlines logo JetSMART Airlines
LATAM Airlines logo LATAM Airlines
Airlines are determined based on actual purchased flight tickets from Santiago to Mendoza according to previous 12 months data from Trip.com.

Search for direct flights from Santiago to Mendoza in the next 3 months. Based on Trip.com's latest 7-day flight data, one-way direct flights start at US$18, and round-trip direct flights start at US$85.

Displayed flight fares from Santiago to Mendoza are based on average prices across airlines for the next 3 months, according to the latest Trip.com database.

Santiago to Mendoza Flight Details

The distance between Santiago and Mendoza is about 195.84 km. The average flying time from Santiago to Mendoza is around 1 hour 9 minutes. Based on Trip.com's latest data, travel demand is highest in July. The off-season for travel is November.

Cheapest one-way flight priceUS$18
Cheapest return ticket priceUS$85
Cheapest monthNovember
Peak season for travelJuly
Flight distance195.84 km
Average flight time1 hour 9 minutes
Popular airlineSky Airline
Flight statistics for the Santiago–Mendoza route are based on aggregated booking data from Trip.com over the past 12 months.

Trip.com Price Insights on Flights from Santiago to Mendoza

Which month has the cheapest one-way flights from Santiago to Mendoza?

Average monthly one-way flight prices from Santiago to Mendoza, based on bookings made by Trip.com users over the past 12 months.

Based on Trip.com’s data, the cheapest month for flights from Santiago to Mendoza is September, with an average price of US$62; while the month with the highest flight price is usually November, with an average price of up to US$86.

US$86
US$74
US$62
US$50
    Cheapest
  • US$81
    Jun
  • US$83
    Jul
  • US$73
    Aug
  • US$62
    Sep
  • US$68
    Oct
  • US$86
    Nov
  • US$77
    Dec
  • US$82
    Jan
  • US$76
    Feb
  • US$66
    Mar
  • US$79
    Apr
  • US$79
    May

Which month has the cheapest round-trip flights from Santiago to Mendoza?

The average price of round-trip flights from Santiago to Mendoza purchased by Trip.com users by month over the past 12 months.

Based on data from Trip.com, the lowest prices for round-trip flights from Santiago to Mendoza are found during September, with an average price of US$136. Conversely, the highest prices are found during July, with an average price of up to US$277.

US$277
US$207
US$136
US$66
    Cheapest
  • US$144
    Jun
  • US$277
    Jul
  • US$168
    Aug
  • US$136
    Sep
  • US$163
    Oct
  • US$160
    Nov
  • US$179
    Dec
  • US$159
    Jan
  • US$152
    Feb
  • US$170
    Mar
  • US$152
    Apr
  • US$165
    May

Frequently Asked Questions

  • What are the cheapest flights from Santiago to Mendoza (SCL-MDZ)?

    Based on Trip.com data, Sky Airline offers one-way fares as low as US$18 on Cheapest nonstop routes (e.g. SCL to MDZ on Mon, Jun 22), while Sky Airline offers Cheapest nonstop round-trips from US$85 departing on Sat, Jul 11 and returning on Mon, Jul 13.
  • At the moment, you can catch a nonstop flight from Santiago to Mendoza with the following airlines, including: Sky Airline JetSMART LATAM Airlines Selected airlines are based on historical data collected from flight bookings users made on Trip.com within the last 90 days.
  • It takes about 1 hour 9 minutes to fly from Santiago to Mendoza.
  • By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Santiago to Mendoza is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.
  • Based on Trip.com data in the past 4 weeks, there is 13 flight per week flying from Santiago to Mendoza. You can check the weekly schedule for popular airlines on this route below: LATAM Airlines: S/M/-/W/T/F/S -- LA434 (09:16)
  • To find best deals on flights from Santiago to Mendoza, you can use various tools on Trip.com:
    · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Mon, Jun 22, with one-way flights priced at just US$18.
    · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is Sky Airline.
    · Set up price alerts to easily monitor ticket prices without having to check every day.
    · Check Trip.com flight deals and promo codes frequently.
    · Avoid peak season unless you book very early. It seems the peak season for Mendoza travel is around July.
    · Get exclusive promo codes for Trip.com app users.
  • The cheapest months to fly from Santiago to Mendoza is November, when demand for travel is lower.
  • After crunching the numbers on our June flight calendar, it's currently cheapest to fly from Santiago to Mendoza on June 21, 2026 with Sky Airline, with prices starting at US$18.
  • You can land at any one of the following hubs in Mendoza, with Arturo Merino Benitez International Airport to El Plumerillo International Airport (SCL-MDZ) is by far the most common option on this route: El Plumerillo International Airport (MDZ).
  • The time difference between Mendoza and Santiago is 1h.
  • Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.

Trip.com Airline Insights on Flights from Santiago to Mendoza

Which airline offers the cheapest direct flights from Santiago to Mendoza?

Data is based on the average price of all nonstop flights from Santiago to Mendoza on Trip.com over the past 12 months.

Based on Trip.com’s data from the past 12 months, JetSMART Airlines provides the lowest-priced direct flights from Santiago to Mendoza, with fares starting at US$78.

US$61
US$78
US$95
US$112
US$129
JetSMART Airlines
US$78
JetSMART Airlines
Sky Airline
US$85
Sky Airline
Aerolineas Argentinas
US$90
Aerolineas Argentinas
LATAM Airlines
US$129
LATAM Airlines

Which airline operates the most flights from Santiago to Mendoza?

Total flights from Santiago to Mendoza across all airlines. (Based on Trip.com data from the past month)

Based on Trip.com’s data from the past month, Iberia/LATAM Airlines operates the most frequent flights from Santiago to Mendoza, with 10 flights per week.

4
6
8
10
Iberia
10
Iberia
LATAM Airlines
10
LATAM Airlines
Sky Airline
9
Sky Airline
JetSMART Airlines
9
JetSMART Airlines
American Airlines
9
American Airlines
Delta Air Lines
6
Delta Air Lines

How many flights fly from Santiago to Mendoza daily?

The data is based on the flight numbers for each day of the week from Santiago to Mendoza within the Trip.com database over the past month.

Based on the past month's historical data from Trip.com, the number of flights from Santiago to Mendoza is the highest on Friday and the lowest on Wednesday.

50
35
20
5
Highest
24
Mon
21
Tue
20
Wed
24
Thu
50
Fri
30
Sat
48
Sun

Note: Prices shown on this page are the estimated lowest prices found in the last 24 hours and include all taxes and fees.

Book with no extra fees

Prices displayed on this page are all-inclusive (incl. taxes, fuel surcharges, Civil Aviation Development Fund, etc.), and all fees are clearly shown before you pay. Charges for checked baggage, onboard meals, Wi‑Fi, and other optional services are also included where applicable in the flight cards.

Real-time pricing updates

Prices, availability, and travel details on this page have been updated within the last 24 hours, and for many routes are refreshed in real time. The more popular the route, the more accurate and up-to-date the data.

Change & Cancellation Policy

Trip.com shows the change and cancellation rules for each ticket during the booking process, including all related fees and conditions. Please refer to the following scenarios:
Voluntary cancellation/change:
To request a change or cancellation, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and flight segment, and submit your request. Please note that additional charges may apply based on the airline’s fare rules.
Cancellation/change due to a flight schedule change:
If your flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For full details of change and cancellation policies, please refer to the customer support pages.