Worldwide Coverage

Worldwide Coverage

Flights to over 5,000 cities
One-stop Service Guarantee

One-stop Service Guarantee

Price guaranteed upon confirmed payment, booking guaranteed once tickets issued
Secure Payment

Secure Payment

Convenient & reliable booking and payment system

Find cheap one-way flights from Santiago to Rome starting at US$473.

Book one-way or return flights from Santiago to Rome from as little as US$473. Choose from the popular airlines below and book your flight today!

  • One way
  • Round-trip

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

When is the cheapest time to book flights from Santiago to Rome?

We monitor flight fares to help you find the best deals effortlessly

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.
Cheapest airlines flights from Santiago to Rome

Compare prices, find the option that best suits your travel needs, and enjoy a comfortable journey with a trusted airline.

LATAM Airlines
From US$393
Avianca
From US$459
Vueling Airlines
From US$473
Copa Airlines
From US$546
JetSMART Airlines
From US$562
Iberia
From US$566
Sky Airline
From US$595
Aerolineas Argentinas
From US$658
British Airways
From US$726
Delta Air Lines
From US$737
ANA airlines

Find more flights and airlines

Find cheap flights from Santiago to Rome by different airports

Searching for potential routes that might be cheaper and faster? Check out these alternative flights from Santiago to Rome.

  • Cheapest
    LATAM Airlines
    SCL
    05:35
    35h 45m
    2 transfer
    FCO
    23:20
    Arturo Merino Benitez Airport - Leonardo da Vinci–Fiumicino Airport
    Fri, Apr 12LATAM Airlines
    US$393
  • LATAM Airlines
    SCL
    19:15
    42h 35m
    2 transfer
    CIA
    19:50
    Arturo Merino Benitez Airport - Ciampino Airport
    Tue, Apr 23LATAM Airlines
    US$652
  • LATAM Airlines
    SCL
    19:15
    42h 35m
    2 transfer
    CIA
    19:50
    Arturo Merino Benitez Airport - Ciampino Airport
    Tue, Apr 23LATAM Airlines
    US$652
    Find More Flights

Frequently Asked Questions

  • When are flight tickets from Santiago (SCL) to Rome (ROM) the cheapest?

    Airlines adjust prices for flights from Santiago to Rome based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.
  • How much do flights from Santiago (SCL) to Rome (ROM) cost?

    According to Trip.com's data, the lowest price is around $1,107.
  • What is the transportation method from the main airport to downtown in Rome?

    • The distance from Leonardo da Vinci–Fiumicino Airport to downtown is about 21km. It takes about 40 minutes by taxi.
    • The distance from Ciampino Airport to downtown is about 13km. It takes about 30 minutes by taxi.

Santiago to Rome Flight Information

Cheapest nonstop flight price

$473

Off-season for travel

November

Peak season for travel

September