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Flights from Santiago to Sao Paulo

Search for direct flights from Santiago to Sao Paulo in the next 3 months. Based on Trip.com's latest 7-day flight data, one-way direct flights start at US$119, and round-trip direct flights start at US$217.

      • Cheapest nonstop
        SCL 04:45
        3h 55m
        Nonstop
        GRU 09:40
        Santiago - Sao Paulo | Thu, Jul 23 | Sky Airline
        GRU 10:45
        4h 30m
        Nonstop
        SCL 14:15
        Sao Paulo - Santiago | Thu, Jul 30 | Sky Airline
        US$217 US$339
        36% off
        36% off
        US$339 US$217
      • SCL 05:00
        3h 55m
        Nonstop
        GRU 09:55
        Santiago - Sao Paulo | Wed, Aug 5 | Sky Airline
        GRU 19:00
        4h 30m
        Nonstop
        SCL 22:30
        Sao Paulo - Santiago | Wed, Aug 12 | Sky Airline
        US$221 US$339
        35% off
        35% off
        US$339 US$221
      • SCL 04:56
        3h 59m
        Nonstop
        GRU 09:55
        Santiago - Sao Paulo | Tue, Aug 25 | JetSMART Airlines
        GRU 19:20
        4h 31m
        Nonstop
        SCL 22:51
        Sao Paulo - Santiago | Wed, Aug 26 | JetSMART Airlines
        US$222 US$339
        35% off
        35% off
        US$339 US$222
      • SCL 04:56
        3h 59m
        Nonstop
        GRU 09:55
        Santiago - Sao Paulo | Thu, Aug 6 | JetSMART Airlines
        GRU 03:25
        4h 30m
        Nonstop
        SCL 06:55
        Sao Paulo - Santiago | Wed, Aug 12 | Sky Airline
        US$223
        34% off
        US$339 US$223
      • SCL 04:56
        3h 59m
        Nonstop
        GRU 09:55
        Santiago - Sao Paulo | Thu, Aug 13 | JetSMART Airlines
        GRU 19:20
        4h 31m
        Nonstop
        SCL 22:51
        Sao Paulo - Santiago | Tue, Aug 18 | JetSMART Airlines
        US$224
        34% off
        US$339 US$224
      • SCL 04:45
        3h 55m
        Nonstop
        GRU 09:40
        Santiago - Sao Paulo | Thu, Aug 13 | Sky Airline
        GRU 19:10
        4h 30m
        Nonstop
        SCL 22:40
        Sao Paulo - Santiago | Sun, Aug 16 | Sky Airline
        US$225
        34% off
        US$339 US$225
      • SCL 04:45
        3h 55m
        Nonstop
        GRU 09:40
        Santiago - Sao Paulo | Sat, Aug 15 | Sky Airline
        GRU 19:00
        4h 30m
        Nonstop
        SCL 22:30
        Sao Paulo - Santiago | Fri, Aug 21 | Sky Airline
        US$225
        34% off
        US$339 US$225
      • SCL 04:45
        3h 55m
        Nonstop
        GRU 09:40
        Santiago - Sao Paulo | Thu, Aug 20 | Sky Airline
        GRU 10:45
        4h 30m
        Nonstop
        SCL 14:15
        Sao Paulo - Santiago | Thu, Aug 27 | Sky Airline
        US$272
        20% off
        US$339 US$272
      • SCL 04:56
        3h 59m
        Nonstop
        GRU 09:55
        Santiago - Sao Paulo | Thu, Aug 20 | JetSMART Airlines
        GRU 19:20
        4h 31m
        Nonstop
        SCL 22:51
        Sao Paulo - Santiago | Mon, Aug 24 | JetSMART Airlines
        US$313
        8% off
        US$339 US$313
      • SCL 05:00
        3h 55m
        Nonstop
        GRU 09:55
        Santiago - Sao Paulo | Thu, Aug 20 | LATAM Airlines
        GRU 19:20
        4h 31m
        Nonstop
        SCL 22:51
        Sao Paulo - Santiago | Mon, Aug 24 | JetSMART Airlines
        US$315
        7% off
        US$339 US$315
      • SCL 13:00
        17h 25m
        1 stop
        SAO 14:00
        Santiago - Sao Paulo | Fri, Jul 24 | Normal Airline
        SAO 15:00
        6h
        Nonstop
        SCL 16:00
        Sao Paulo - Santiago | Sun, Jul 26 | Normal Airline
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      • Cheapest nonstop
        SCL 21:30
        3h 55m
        Nonstop
        GRU 02:25
        Santiago - Sao Paulo | Wed, Aug 12 | Sky Airline
        US$119 US$142
        16% off
        16% off
        US$142 US$119
      • SCL 13:21
        3h 59m
        Nonstop
        GRU 18:20
        Santiago - Sao Paulo | Sat, Aug 8 | JetSMART Airlines
        US$121 US$142
        15% off
        15% off
        US$142 US$121
      • SCL 21:30
        3h 55m
        Nonstop
        GRU 02:25
        Santiago - Sao Paulo | Wed, Aug 19 | Sky Airline
        US$121 US$142
        15% off
        15% off
        US$142 US$121
      • SCL 04:45
        3h 55m
        Nonstop
        GRU 09:40
        Santiago - Sao Paulo | Sun, Aug 16 | Sky Airline
        US$121
        15% off
        US$142 US$121
      • SCL 13:00
        3h 55m
        Nonstop
        GRU 17:55
        Santiago - Sao Paulo | Mon, Aug 31 | Sky Airline
        US$121
        15% off
        US$142 US$121
      • SCL 04:46
        3h 59m
        Nonstop
        GRU 09:45
        Santiago - Sao Paulo | Sun, Aug 16 | JetSMART Airlines
        US$122
        14% off
        US$142 US$122
      • SCL 04:45
        3h 55m
        Nonstop
        GRU 09:40
        Santiago - Sao Paulo | Fri, Aug 14 | Sky Airline
        US$122
        14% off
        US$142 US$122
      • SCL 06:06
        3h 59m
        Nonstop
        GRU 11:05
        Santiago - Sao Paulo | Sat, Aug 15 | JetSMART Airlines
        US$123
        13% off
        US$142 US$123
      • SCL 06:35
        3h 50m
        Nonstop
        GRU 10:25
        Santiago - Sao Paulo | Sat, Sep 12 | JetSMART Airlines
        US$132
        7% off
        US$142 US$132
      • SCL 13:00
        3h 55m
        Nonstop
        GRU 17:55
        Santiago - Sao Paulo | Sat, Aug 15 | Sky Airline
        US$132
        7% off
        US$142 US$132
      • SCL 13:00
        17h 25m
        1 stop
        SAO 14:00
        Santiago - Sao Paulo | Fri, Jul 24 | Normal Airline
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        Find more flights

Cheapest airlines flights from Santiago to Sao Paulo

You can choose from 5 airlines that fly from Santiago to Sao Paulo, including LATAM Airlines, JetSMART Airlines, and Turkish Airlines. Sky Airline has lowest fares on this route.
LATAM Airlines logo LATAM Airlines
JetSMART Airlines logo JetSMART Airlines
Turkish Airlines logo Turkish Airlines
Gol Linhas Aereas Inteligentes logo Gol Linhas Aereas Inteligentes
Aerolineas Argentinas logo Aerolineas Argentinas
Airlines are determined based on actual purchased flight tickets from Santiago to Sao Paulo according to previous 12 months data from Trip.com.

Santiago to Sao Paulo Flight Details

The distance between Santiago and Sao Paulo is about 2,595.22 km. The average flying time from Santiago to Sao Paulo is around 4 hours 2 minutes. Based on Trip.com's latest data, travel demand is highest in January. The off-season for travel is December.

Cheapest one-way flight price US$119
Cheapest return ticket price US$217
Cheapest month December
Peak season for travel January
Flight distance 2,595.22 km
Average flight time 4 hours 2 minutes
Popular airline LATAM Airlines
Flight statistics for the Santiago–Sao Paulo route are based on aggregated booking data from Trip.com over the past 12 months.

Trip.com Price Insights on Flights from Santiago to Sao Paulo

Which month has the cheapest one-way flights from Santiago to Sao Paulo?

Average monthly one-way flight prices from Santiago to Sao Paulo, based on bookings made by Trip.com users over the past 12 months.

Based on Trip.com’s data, the cheapest month for flights from Santiago to Sao Paulo is October, with an average price of US$154; while the month with the highest flight price is usually April, with an average price of up to US$300.

US$300
US$227
US$154
US$81
    Cheapest
  • US$233
    Jul
  • US$185
    Aug
  • US$194
    Sep
  • US$154
    Oct
  • US$174
    Nov
  • US$176
    Dec
  • US$286
    Jan
  • US$242
    Feb
  • US$214
    Mar
  • US$300
    Apr
  • US$260
    May
  • US$194
    Jun

Which month has the cheapest round-trip flights from Santiago to Sao Paulo?

The average price of round-trip flights from Santiago to Sao Paulo purchased by Trip.com users by month over the past 12 months.

Based on data from Trip.com, the lowest prices for round-trip flights from Santiago to Sao Paulo are found during September, with an average price of US$298. Conversely, the highest prices are found during January, with an average price of up to US$547.

US$547
US$423
US$298
US$174
    Cheapest
  • US$349
    Jul
  • US$363
    Aug
  • US$298
    Sep
  • US$315
    Oct
  • US$342
    Nov
  • US$375
    Dec
  • US$547
    Jan
  • US$364
    Feb
  • US$328
    Mar
  • US$415
    Apr
  • US$373
    May
  • US$316
    Jun

Frequently Asked Questions

  • What are the cheapest flights from Santiago to Sao Paulo (SCL-SAO)?

    Based on Trip.com data, Sky Airline offers one-way fares as low as US$119 on Cheapest nonstop routes (e.g. SCL to GRU on Wed, Aug 12), while Sky Airline offers Cheapest nonstop round-trips from US$217 departing on Thu, Jul 23 and returning on Thu, Jul 30.
  • At the moment, you can catch a nonstop flight from Santiago to Sao Paulo with the following airlines, including: LATAM Airlines JetSMART Turkish Airlines Selected airlines are based on historical data collected from flight bookings users made on Trip.com within the last 90 days.
  • It takes about 4 hours 2 minutes to fly from Santiago to Sao Paulo.
  • By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Santiago to Sao Paulo is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.
  • Based on Trip.com data in the past 4 weeks, there is 118 flight per week flying from Santiago to Sao Paulo. You can check the weekly schedule for popular airlines on this route below: Turkish Airlines: S/M/T/W/T/F/S -- TK216 (10:51)
  • To find best deals on flights from Santiago to Sao Paulo, you can use various tools on Trip.com:
    · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Wed, Aug 12, with one-way flights priced at just US$119.
    · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is Sky Airline.
    · Set up price alerts to easily monitor ticket prices without having to check every day.
    · Check Trip.com flight deals and promo codes frequently.
    · Avoid peak season unless you book very early. It seems the peak season for Sao Paulo travel is around January.
    · Get exclusive promo codes for Trip.com app users.
  • The cheapest months to fly from Santiago to Sao Paulo is December, when demand for travel is lower.
  • After crunching the numbers on our July flight calendar, it's currently cheapest to fly from Santiago to Sao Paulo on July 25, 2026 with Sky Airline, with prices starting at US$90.
  • You can land at any one of the following hubs in Sao Paulo, with Arturo Merino Benitez International Airport to São Paulo/Guarulhos–Governor André Franco Montoro International Airport (SCL-GRU) is by far the most common option on this route: São Paulo–Congonhas Airport (CGH) São Paulo/Guarulhos–Governor André Franco Montoro International Airport (GRU) Viracopos International Airport (VCP).
  • The time difference between Sao Paulo and Santiago is 1h.
  • Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.

Trip.com Airline Insights on Flights from Santiago to Sao Paulo

Which airline offers the cheapest direct flights from Santiago to Sao Paulo?

Data is based on the average price of all nonstop flights from Santiago to Sao Paulo on Trip.com over the past 12 months.

Based on Trip.com’s data from the past 12 months, Sky Airline provides the lowest-priced direct flights from Santiago to Sao Paulo, with fares starting at US$159.

US$123
US$159
US$196
US$233
US$269
Sky Airline
US$159
Sky Airline
JetSMART Airlines
US$166
JetSMART Airlines
Aerolineas Argentinas
US$221
Aerolineas Argentinas
Turkish Airlines
US$257
Turkish Airlines
LATAM Airlines
US$269
LATAM Airlines

Which airline operates the most flights from Santiago to Sao Paulo?

Total flights from Santiago to Sao Paulo across all airlines. (Based on Trip.com data from the past month)

Based on Trip.com’s data from the past month, LATAM Airlines operates the most frequent flights from Santiago to Sao Paulo, with 80 flights per week.

0
16
48
80
LATAM Airlines
80
LATAM Airlines
Qantas Airways
61
Qantas Airways
Delta Air Lines
45
Delta Air Lines
JetSMART Airlines
25
JetSMART Airlines
Sky Airline
16
Sky Airline
British Airways
16
British Airways

How many flights fly from Santiago to Sao Paulo daily?

The data is based on the flight numbers for each day of the week from Santiago to Sao Paulo within the Trip.com database over the past month.

Based on the past month's historical data from Trip.com, the number of flights from Santiago to Sao Paulo is the highest on Saturday and the lowest on Tuesday.

165
147
129
111
Highest
130
Mon
129
Tue
134
Wed
133
Thu
159
Fri
165
Sat
149
Sun

Explore More Popular Flights

Note: Prices shown on this page are the estimated lowest prices found in the last 24 hours and include all taxes and fees.

Book with no extra fees

Prices displayed on this page are all-inclusive (incl. taxes, fuel surcharges, Civil Aviation Development Fund, etc.), and all fees are clearly shown before you pay. Charges for checked baggage, onboard meals, Wi‑Fi, and other optional services are also included where applicable in the flight cards.

Real-time pricing updates

Prices, availability, and travel details on this page have been updated within the last 24 hours, and for many routes are refreshed in real time. The more popular the route, the more accurate and up-to-date the data.

Change & Cancellation Policy

Trip.com shows the change and cancellation rules for each ticket during the booking process, including all related fees and conditions. Please refer to the following scenarios:
Voluntary cancellation/change:
To request a change or cancellation, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and flight segment, and submit your request. Please note that additional charges may apply based on the airline’s fare rules.
Cancellation/change due to a flight schedule change:
If your flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For full details of change and cancellation policies, please refer to the customer support pages.