Cheapest airlines flights from Santo Domingo to Madrid

You can choose from 1 airlines that fly from Santo Domingo to Madrid, including Iberia, Iberia has lowest fares on this route.
Iberia logo Iberia
Airlines are determined based on actual purchased flight tickets from Santo Domingo to Madrid according to previous 12 months data from Trip.com.

Search for direct flights from Santo Domingo to Madrid in the next 3 months. Based on Trip.com's latest 7-day flight data, one-way direct flights start at US$410, and round-trip direct flights start at US$640.

Displayed flight fares from Santo Domingo to Madrid are based on average prices across airlines for the next 3 months, according to the latest Trip.com database.

Santo Domingo to Madrid Flight Details

The distance between Santo Domingo and Madrid is about 6,706.66 km. The average flying time from Santo Domingo to Madrid is around 8 hours 31 minutes. Based on Trip.com's latest data, travel demand is highest in January. The off-season for travel is December.

Cheapest one-way flight priceUS$410
Cheapest return ticket priceUS$640
Cheapest monthDecember
Peak season for travelJanuary
Flight distance6,706.66 km
Average flight time8 hours 31 minutes
Popular airlineIberia
Flight statistics for the Santo Domingo–Madrid route are based on aggregated booking data from Trip.com over the past 12 months.

Trip.com Price Insights on Flights from Santo Domingo to Madrid

Which month has the cheapest one-way flights from Santo Domingo to Madrid?

The average price of one-way flights from Santo Domingo to Madrid purchased by Trip.com users by month over the past 12 months.

Based on Trip.com’s data, the cheapest month for flights from Santo Domingo to Madrid is November, with an average price of US$375; while the month with the highest flight price is usually April, with an average price of up to US$944.

US$944
US$660
US$375
US$91
    Cheapest
  • US$944
    Apr
  • US$749
    May
  • US$404
    Jun
  • US$459
    Jul
  • US$745
    Aug
  • US$861
    Sep
  • US$522
    Oct
  • US$375
    Nov
  • US$407
    Dec
  • US$864
    Jan
  • US$725
    Feb
  • US$698
    Mar

Which month has the cheapest round-trip flights from Santo Domingo to Madrid?

The average price of round-trip flights from Santo Domingo to Madrid purchased by Trip.com users by month over the past 12 months.

Based on data from Trip.com, the lowest prices for round-trip flights from Santo Domingo to Madrid are found during November, with an average price of US$721. Conversely, the highest prices are found during January, with an average price of up to US$1,350.

US$1,350
US$1,036
US$721
US$407
    Cheapest
  • US$1,099
    Apr
  • US$1,035
    May
  • US$949
    Jun
  • US$910
    Jul
  • US$1,182
    Aug
  • US$1,080
    Sep
  • US$949
    Oct
  • US$721
    Nov
  • US$730
    Dec
  • US$1,350
    Jan
  • US$1,041
    Feb
  • US$1,109
    Mar

What is the cheapest day of the week to fly from Santo Domingo to Madrid?

Average weekly flight prices from Santo Domingo to Madrid by travel date (Based on Trip.com’s past 12 months of data)

Based on Trip.com’s past 12 months of flight data, the cheapest day to fly from Santo Domingo to Madrid is Thursday, with average prices lower than on other days. Avoid Friday, as prices are usually highest then.

US$896
US$722
US$547
US$373
    Cheapest
  • US$630
    Mon
  • US$596
    Tue
  • US$717
    Wed
  • US$547
    Thu
  • US$896
    Fri
  • US$614
    Sat
  • US$550
    Sun

When is the cheapest day to fly from Santo Domingo to Madrid during International Workers' Day?

Based on Trip.com's data over the past 3 days, these are the lowest one-way flight prices from Santo Domingo to Madrid during International Workers' Day.

International Workers' Day is scheduled for May 1. The cheapest flights from Santo Domingo to Madrid are available on Apr 28, with fares starting at US$479.

US$552
US$516
US$479
US$443
  • US$502
    27
    Apr
  • US$479
    28
  • US$517
    29
  • US$552
    30
  • US$531
    1
    May
  • US$550
    2
  • US$500
    3

Frequently Asked Questions

  • What are the cheapest flights from Santo Domingo to Madrid (SDQ-MAD)?

    Based on Trip.com data, Iberia offers one-way fares as low as US$410 on Cheapest nonstop routes (e.g. SDQ to MAD on Thu, Jun 4), while World2Fly Airlines offers Cheapest nonstop round-trips from US$640 departing on Fri, May 15 and returning on Fri, May 22.
  • At the moment, you can catch a nonstop flight from Santo Domingo to Madrid with the following airlines, including: Iberia Selected airlines are based on historical data collected from flight bookings users made on Trip.com within the last 90 days.
  • It takes about 8 hours 31 minutes to fly from Santo Domingo to Madrid.
  • By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Santo Domingo to Madrid is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.
  • Based on Trip.com data in the past 4 weeks, there is 24 flight per week flying from Santo Domingo to Madrid. You can check the weekly schedule for popular airlines on this route below: Iberia: S/M/T/W/T/F/S -- IB266 (17:22)
  • To find best deals on flights from Santo Domingo to Madrid, you can use various tools on Trip.com:
    · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Thu, Jun 4, with one-way flights priced at just US$410.
    · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is Iberia.
    · Set up price alerts to easily monitor ticket prices without having to check every day.
    · Check Trip.com flight deals and promo codes frequently.
    · Avoid peak season unless you book very early. It seems the peak season for Madrid travel is around January.
    · Get exclusive promo codes for Trip.com app users.
  • The cheapest months to fly from Santo Domingo to Madrid is December, when demand for travel is lower.
  • After crunching the numbers on our April flight calendar, it's currently cheapest to fly from Santo Domingo to Madrid on April 22, 2026 with Arajet Airline, with prices starting at US$386.
  • You can land at any one of the following hubs in Madrid, with Las Américas International Airport to Madrid Barajas Airport (SDQ-MAD) is by far the most common option on this route: Madrid Barajas Airport (MAD).
  • The time difference between Madrid and Santo Domingo is 5h.
  • Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.

Trip.com Airline Insights on Flights from Santo Domingo to Madrid

Which airline offers the cheapest direct flights from Santo Domingo to Madrid?

Data is based on the average price of all nonstop flights from Santo Domingo to Madrid on Trip.com over the past 12 months.

Based on Trip.com’s data from the past 12 months, Hahn Air provides the lowest-priced direct flights from Santo Domingo to Madrid, with fares starting at US$523.

US$211
US$523
US$836
US$1,149
US$1,461
Hahn Air
US$523
Hahn Air
World2Fly Airlines
US$543
World2Fly Airlines
American Airlines
US$717
American Airlines
Iberia
US$806
Iberia
Air Europa
US$832
Air Europa
avianca
US$1,461
avianca

Which airline operates the most flights from Santo Domingo to Madrid?

Total flights from Santo Domingo to Madrid across all airlines. (Based on Trip.com data from the past month)

Based on Trip.com’s data from the past month, Qatar Airways/Iberia operates the most frequent flights from Santo Domingo to Madrid, with 16 flights per week.

4
8
12
16
Qatar Airways
16
Qatar Airways
Iberia
16
Iberia
Air Europa
13
Air Europa
British Airways
10
British Airways
Etihad Airways
8
Etihad Airways
Turkish Airlines
8
Turkish Airlines

How many flights fly from Santo Domingo to Madrid daily?

The data is based on the flight numbers for each day of the week from Santo Domingo to Madrid within the Trip.com database over the past month.

Based on the past month's historical data from Trip.com, the number of flights from Santo Domingo to Madrid is the highest on Saturday and the lowest on Wednesday.

59
52
44
37
Highest
46
Mon
50
Tue
44
Wed
54
Thu
56
Fri
59
Sat
58
Sun

Note: Prices shown on this page are the estimated lowest prices found in the last 24 hours and include all taxes and fees.

Book with no extra fees

Prices displayed on this page are all-inclusive (incl. taxes, fuel surcharges, Civil Aviation Development Fund, etc.), and all fees are clearly shown before you pay. Charges for checked baggage, onboard meals, Wi‑Fi, and other optional services are also included where applicable in the flight cards.

Real-time pricing updates

Prices, availability, and travel details on this page have been updated within the last 24 hours, and for many routes are refreshed in real time. The more popular the route, the more accurate and up-to-date the data.

Change & Cancellation Policy

Trip.com shows the change and cancellation rules for each ticket during the booking process, including all related fees and conditions. Please refer to the following scenarios:
Voluntary cancellation/change:
To request a change or cancellation, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and flight segment, and submit your request. Please note that additional charges may apply based on the airline’s fare rules.
Cancellation/change due to a flight schedule change:
If your flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For full details of change and cancellation policies, please refer to the customer support pages.