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American Airlines(AA) flights from Charlotte to Des Moines

Flight INFO & American Airlines(AA) flights from Charlotte to Des Moines

Cheapest one-way flight price US$224
Cheapest return ticket price US$423
Cheapest month September
Peak season for travel December
Flight distance 1,310.31 km
Average flight time 2 hours 33 minutes
Frequency ～14/week

Book American Airlines(AA) flights from Charlotte to Des Moines

  • One way
  • Round-trip
      • direct cheapest
        CLT22:25
        2h 33m
        Nonstop
        DSM23:58
        Charlotte - Des Moines|Wed, Oct 21|American Airlines
        US$488
        US$813
        40% off
        Search
        40% off
        US$813
        US$488
      • CLT21:57
        2h 29m
        Nonstop
        DSM23:26
        Charlotte - Des Moines|Mon, Nov 9|American Airlines
        US$562
        US$813
        31% off
        Search
        31% off
        US$813
        US$562
      • CLT22:25
        2h 33m
        Nonstop
        DSM23:58
        Charlotte - Des Moines|Mon, Oct 19|American Airlines
        US$565
        US$813
        31% off
        Search
        31% off
        US$813
        US$565
      • CLT09:09
        2h 33m
        Nonstop
        DSM10:42
        Charlotte - Des Moines|Thu, Oct 22|American Airlines
        US$577
        Search
        US$577
      • CLT14:54
        10h 32m
        1 stops
        DSM00:26
        Charlotte - Des Moines|Thu, Nov 12|American Airlines
        US$224
        Search
        US$224
      • CLT22:55
        11h 1m
        1 stops
        DSM08:56
        Charlotte - Des Moines|Wed, Oct 28|American Airlines
        US$225
        Search
        US$225
      • CLT09:43
        10h 17m
        1 stops
        DSM19:00
        Charlotte - Des Moines|Tue, Oct 20|American Airlines
        US$248
        Search
        US$248
      • CLT22:50
        11h 6m
        1 stops
        DSM08:56
        Charlotte - Des Moines|Mon, Oct 26|American Airlines
        US$248
        Search
        US$248
      • CLT11:00
        9h
        1 stops
        DSM19:00
        Charlotte - Des Moines|Sat, Oct 31|American Airlines
        US$274
        Search
        US$274
      • CLT14:54
        10h 20m
        1 stops
        DSM00:14
        Charlotte - Des Moines|Mon, Nov 2|American Airlines
        US$316
        Search
        US$316
      • CLT22:49
        10h 57m
        1 stops
        DSM08:46
        Charlotte - Des Moines|Fri, Nov 6|American Airlines
        US$347
        Search
        US$347
      • CLT09:40
        15h 46m
        1 stops
        DSM00:26
        Charlotte - Des Moines|Fri, Nov 13|American Airlines
        US$400
        Search
        US$400
      • CLT11:00
        8h 54m
        1 stops
        DSM18:54
        Charlotte - Des Moines|Sun, Nov 1|American Airlines
        US$448
        Search
        US$448
      • CLT09:43
        15h 31m
        1 stops
        DSM00:14
        Charlotte - Des Moines|Fri, Oct 30|American Airlines
        US$450
        Search
        US$450
      • CLT13:00
        15h 31m
        Nonstop
        DSM14:00
        Charlotte - Des Moines|Mon, Sep 6|Normal Airline
        More cheap flights
        More cheap flights

American Airlines(AA) flights from Charlotte to Des Moines & Flight Schedule

Flight info.
Departure
Arrival
Weekly Schedule

  1. AA1393

    American Airlines

    16:35

    CLT

    2.5h

    Nonstop

    18:08

    DSM

    S - T W T F S
    Search

  2. AA2962

    American Airlines

    08:59

    CLT

    2.3h

    Nonstop

    10:19

    DSM

    S M T W T - S
    Search

  3. AA1038

    American Airlines

    10:57

    CLT

    2.3h

    Nonstop

    12:14

    ORD

    S M T W T F S
    Search

  4. AA4510

    American Airlines

    17:20

    ORD

    1.7h

    Nonstop

    19:00

    DSM

    S M T W T F S
    Search

  5. AA2534

    American Airlines

    09:43

    CLT

    2.4h

    Nonstop

    11:05

    ORD

    S M T W T F S
    Search

  6. AA4510

    American Airlines

    17:20

    ORD

    1.7h

    Nonstop

    19:00

    DSM

    S M T W T F S
    Search

  7. AA627

    American Airlines

    22:55

    CLT

    2.3h

    Nonstop

    00:13

    ORD

    S M T W T F S
    Search

  8. AA4955

    American Airlines

    07:17

    ORD

    1.6h

    Nonstop

    08:56

    DSM

    S M T W T F S
    Search

  9. AA2530

    American Airlines

    16:18

    CLT

    2.4h

    Nonstop

    17:39

    ORD

    S M T W T F S
    Search

  10. AA4548

    American Airlines

    22:40

    ORD

    1.6h

    Nonstop

    00:14

    DSM

    S M T W T F S
    Search

  11. AA2534

    American Airlines

    09:43

    CLT

    2.4h

    Nonstop

    11:05

    ORD

    S M T W T F S
    Search

  12. AA4548

    American Airlines

    22:40

    ORD

    1.6h

    Nonstop

    00:14

    DSM

    S M T W T F S
    Search
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American Airlines(AA) flights from Charlotte to Des Moines Flight Booking FAQ

  • How long is a flight from Charlotte to Des Moines?

    It takes about 2 hours 33 minutes to fly from Charlotte to Des Moines.

  • When is the best time to book flights from Charlotte to Des Moines?

    By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Charlotte to Des Moines is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.

  • When are flight tickets from Charlotte (CLT) to Des Moines (DSM) the cheapest?

    The cheapest months to fly from Charlotte to Des Moines is September, when demand for travel is lower.

  • Which upcoming date is cheapest to fly from Charlotte to Des Moines on?

    After crunching the numbers on our October flight calendar, it's currently cheapest to fly from Charlotte to Des Moines on October 22, 2026 with American Airlines, with prices starting at US$485.

  • Is there any time difference between Charlotte and Des Moines?

    The time difference between Des Moines and Charlotte is 1h.

  • How do I change or cancel my ticket from Charlotte to Des Moines?

    Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.