Flights from St. Louis(STL) to St. Pete-Clearwater International Airport(PIE)

At the moment, several airlines serve connecting flights from St. Louis to Tampa, including: American Airlines Selected airlines are based on historical data collected from flight bookings made by users on Trip.com within the last 90 days.

It takes about 2 hours 28 minutes to fly from St. Louis to Tampa.

By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from St. Louis to Tampa is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.

The cheapest months to fly from St. Louis to Tampa is October, when demand for travel is lower.

After crunching the numbers on our September flight calendar, it's currently cheapest to fly from St. Louis to Tampa on September 21, 2026 with Frontier Airlines, with prices starting at US$50.

You can land at any one of the following hubs in Tampa: St. Pete–Clearwater International Airport (PIE), and Tampa International Airport (TPA). Flying from St. Louis Lambert International Airport to Tampa International Airport (STL-TPA) is by far the most common option on this route.

The time difference between Tampa and St. Louis is 1h.

Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.