Find Spirit Airlines(NK) flights from Houston to Panama City

It takes about 3 hours 41 minutes to fly from Houston to Panama City.

By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Houston to Panama City is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.

The cheapest months to fly from Houston to Panama City is September, when demand for travel is lower.

After crunching the numbers on our October flight calendar, it's currently cheapest to fly from Houston to Panama City on October 19, 2026 with Volaris, with prices starting at US$718.

The time difference between Panama City and Houston is 1h.

Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.