Hilton Jacksonville at Mayo Clinic
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Hilton Jacksonville at Mayo Clinic

Discover Hilton Jacksonville at Mayo Clinic, an 4-star stay in Jacksonville. With a score of 8.8/10 based on 21 reviews, it offers an outstanding blend of quality and value, with prices starting from US$181.

Check-In & Check-Out

From 16:00 until 11:00

Nearby Attractions

The Church of Eleven22 - San Pablo Campus: 2.83 km away

Chets Creek Church - Hodges Campus: 2.35 km away

Shipwreck Island Water Park: 4.17 km away

Amenity Highlights

Food & Drink: Room service, Restaurant, Convenience store/kiosk, Bar

Hilton Jacksonville at Mayo Clinic

Opened in 2025
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We Price Match
Highlights
Buffet breakfasts
Bathtub
Newly opened
Suite
Outdoor pool
+3 more
Amenities
All amenities
Property Description
Show more
Cleanliness9.4
Amenities9.4
Location9.4
Service9.4
Surroundings
Airport: Naval Air Station Jacksonville
(40.0 km)
Airport: Jacksonville International Airport
(44.2 km)
Train: FECR
(18.3 km)
Landmarks: Chets Creek Church - Hodges Campus
(2.4 km)
Landmarks: The Church of Eleven22 - San Pablo Campus
(2.8 km)
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8

Room With Two Queen Beds-Hearing Accessible

2 Queen bed
Has window
Non-smoking
Air conditioning
Private bathroom
Refrigerator
Towels
Room Details
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6

Mobility Accessible Room With 2 Queen Beds And Water View And Bathtub

2 Queen bed
Has window
Non-smoking
Air conditioning
Private bathroom
Bathtub
Refrigerator
Room Details
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7

Room With 2 Queen Beds And Water View

2 Queen bed
Has window
Non-smoking
Air conditioning
Private bathroom
Refrigerator
Towels
Room Details
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7

Room With 2 Queen Beds And Bathtub-Mobility Accessible

2 Queen bed
Has window
Non-smoking
Air conditioning
Private bathroom
Bathtub
Refrigerator
Room Details
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7

King Room With Roll-in Shower-Mobility Accessible

1 King bed
Has window
Non-smoking
Air conditioning
Private bathroom
Refrigerator
Lowered sink
Room Details
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7

2 Queen Water View Hearing Accessible Room

2 Queen bed
Has window
Non-smoking
Air conditioning
Private bathroom
Refrigerator
Towels
Room Details
Check Availability
8

King Room With Roll-in Shower And Water View-Mobility Accessible

1 King bed
Has window
Non-smoking
Air conditioning
Private bathroom
Refrigerator
Lowered sink
Room Details
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11

King Room-Hearing Accessible

1 King bed
Has window
Non-smoking
Air conditioning
Private bathroom
Refrigerator
Towels
Room Details
Check Availability
8

2 Queen Beds Room

2 Queen bed
Has window
Non-smoking
Air conditioning
Private bathroom
Refrigerator
Towels
Room Details
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4

1 Kng Jr Ste Mobility/ Hearing Acesss Ri Shwr

1 King bed
Has window
Non-smoking
Air conditioning
Refrigerator
Room Details
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7

1 King Bed Water View Hearing Accessible

1 King bed
Has window
Non-smoking
Air conditioning
Private bathroom
Refrigerator
Microwave
Room Details
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10

King Room With Water View

1 King bed
Has window
Non-smoking
Air conditioning
Private bathroom
Refrigerator
Towels
Room Details
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6

1 King Bed Corner Junior Suite Water View

1 King bed
Has window
Non-smoking
Air conditioning
Private bathroom
Bathtub
Refrigerator
Room Details
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5

Corner Junior Suite With King Bed And Roll-in Shower-Mobility Accessible

1 King bed
Has window
Non-smoking
Air conditioning
Private bathroom
Refrigerator
Lowered sink
Room Details
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1

Corner Kg Jr Mobility

1 King bed
Has window
Non-smoking
Room Details
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5

Junior King Suite With Mobility Accessible Roll-in Shower

1 King bed
Has window
Non-smoking
Air conditioning
Private bathroom
Bathtub
Refrigerator
Room Details
Check Availability
7

1 King Dlx Water View Mobility Access Ri Shwr

1 King bed
Has window
Non-smoking
Air conditioning
Private bathroom
Refrigerator
Lowered sink
Room Details
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6

1 King Bed Junior Suite Open Floor Plan

1 King bed
Has window
Non-smoking
Air conditioning
Private bathroom
Refrigerator
Microwave
Room Details
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8

1 King Bed With Chaise

1 King bed
Has window
Non-smoking
Air conditioning
Private bathroom
Refrigerator
Microwave
Room Details
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6

1 King Bed Deluxe Water View With Sofa

1 King bed
Has window
Non-smoking
Air conditioning
Private bathroom
Refrigerator
Microwave
Room Details
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Average for similar properties in Jacksonville
A‍l‍i‍s‍o‍n
March 9, 2026
Overall the hotel was very nice. The only negative was the mattress. It was pretty uncomfortable in my opinion.
L‍o‍r‍i
March 3, 2026
I had the pleasure of being checked in by a wonderful ambassador for Hilton, Harley. Her Customer Service skills were something straight out of an outstanding customer service training video! On my way out, I had the pleasure of meeting another Hilton ambassador, Monica. I am a business traveler, and I truly want to convey how incredibly genuine both of these ladies were. It’s what I refer to as “good old Customer Service” and that’s very hard to find these days.
D‍a‍v‍i‍d
February 25, 2026
Checkin was slow only because their systems were down due to internet being down. Everyone looking to checkin waited. However, the staff handled it with excellence and manually checked everyone in and walked us to our rooms. It truly was a technical issue that they had no control over. The rooms were very clean and comfortable.
Y‍a‍n
March 6, 2026
Nice hotel, but disappointing service. I had to leave at 6:15 AM for an emergency and couldn't wait for the 6:30 breakfast I'd already paid for. I asked the attendant for just a coffee or a quick snack to go, but she refused and only gave me ice water. Not the best experience on a freezing cold morning!"
J‍a‍c‍q‍u‍e‍l‍i‍n‍e
February 28, 2026
The rooms were not clean and housekeeping did not clean toilets nor the bathroom sink did not sweep the floors they just make the bed and that’s it
D‍i‍a‍n‍e
February 11, 2026
Friendly welcoming staff at the front desk and the restaurant! Immaculate! Comfy bedding and pillows!
J‍o‍A‍n‍n
January 13, 2026
The overall experience was excellent. The room was well maintained and clean. The staff were extremely helpful and accommodating. The experience was so positive that earlier today I booked a stay at a Hilton in the city of a conference I will be attending in the Spring.
D‍a‍i‍s‍y
January 25, 2026
Loved this hotel! Great location - friendly staff- yummy food and drinks at Coastal restaurant- hire and rooms are so nice and clean - pool and gym area were a plus! Coffee spot and shuttle also nice to have available.
F‍r‍e‍d‍e‍r‍i‍c‍k
December 21, 2025
The accommodations were comfortable. Our only "complaint' might be that there needed to be more staff at the front desk in the evening. Because we had an early morning medical appt. we knew we would not be able to have breakfast at the hotel, so we opted to purchase frozen sausage/egg biscuits the night before to heat up in our room. There was no staff at the store at that time and only one at the front desk. The line was 3 deep and we had to wait a long time to pay for these, as the one of the guests in front of us had a lengthy encounter at the desk. Perhaps a self-pay option would be helpful.

Services & Amenities

Restaurant
No additional info available

Property Policies

Check-in and Check-out Times
Check-in: After 16:00
Check-out: Before 11:00

Front desk hours: 24/7

Child policies
Children of all ages are welcome at this property.
Additional fees may be charged for children using existing beds. Add the number of children to get a more accurate price.

Cribs and Extra Beds
Extra bed and crib policies may vary according to room type. Please refer to the room type details for more information.

Breakfast
StyleBuffet
Opening hours[Mon - Sun] 06:00-10:30 Open
AgeFee
Adult
Buffet:US$26.99 per person
Additional breakfast fees are not included in the total and need to be paid at the property.

Deposit Policy
DepositDeposit required
Deposit Collection MethodsThe deposit is determined based on the duration of your stay. The charge is US$100.00 per night.

Age Requirements
The main guest checking in must be at least 21 years old

Property Description

Local hotel name: Hilton Jacksonville at Mayo Clinic
  • Opened: 2025
  • Number of Rooms: 252
Phone:+1-904-9299000
Email:JAXMO_HOTEL@hilton.com
Located on the Mayo Clinic Jacksonville Campus and less than a mile from Mayo Clinic Hospital, our hotel offers easy access to top medical facilities. We’re six miles from Jacksonville Beaches and eight miles from St. Johns Town Center. Relax in our heated outdoor pool or host events in our 16,000 sq ft of indoor space and 5,000 sq ft of outdoor patio area.

You might be wondering

What are the check-in and check-out times at Hilton Jacksonville at Mayo Clinic?

Check-in time at Hilton Jacksonville at Mayo Clinic starts at 16:00, and check-out time is by 11:00.

Does Hilton Jacksonville at Mayo Clinic have a pool?

Yes, Hilton Jacksonville at Mayo Clinic has a swimming pool for guests.

How much does it cost to stay at Hilton Jacksonville at Mayo Clinic?

Room prices at Hilton Jacksonville at Mayo Clinic vary by travel dates, hotel policy, and other factors. Enter your travel dates to see current prices.

How to get to Hilton Jacksonville at Mayo Clinic from the nearest airport?

The nearest airport is Naval Air Station Jacksonville, located about 27 mins from hotel by car (40.0 km) away.

What’s the cancellation policy at Hilton Jacksonville at Mayo Clinic?

The cancellation policy at Hilton Jacksonville at Mayo Clinic depends on your room type and booking terms.

About This Property

Nearest AirportNaval Air Station Jacksonville
Distance to Airport39.99KM
Nearest Train StationKings Avenue Station
Distance to Train Station25.98KM
Average Price FromUSD386
Hotel Star Rating4