21C Museum Hotel St Louis
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21C Museum Hotel St Louis

Discover 21C Museum Hotel St Louis, an 4-star stay in St. Louis. With a score of 8.9/10 based on 110 reviews, it offers an outstanding blend of quality and value, with prices starting from US$135.

Check-In & Check-Out

From 16:00 until 11:00

Nearby Attractions

Memorial Plaza: 0.37 km away

City Museum: 0.28 km away

Aloe Plaza: 0.51 km away

Amenity Highlights

Leisure: Gaming area, Spa, Billiards room

Food & Drink: Room service, Restaurant, Bar

21C Museum Hotel St Louis

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We Price Match
Highlights
Loft
Spa
Lounge
Indoor pool
Ideal location
+5 more
Amenities
All amenities
Property Description
Show more
Love it a lot. I even extended my stay. The breakfast is also very yummmm!
Surroundings
Airport: St. Louis Lambert International Airport
(30.9 km)
Train: Union Station
(890m)
Train: Civic Center
(1.0 km)
Landmarks: City Museum
(280m)
Landmarks: Memorial Plaza
(370m)
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4

Corner King Suite

1 King bed
Non-smoking
Wi-Fi in room
Smart door lock
Bathtub or shower
Room Details
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6

Luxury Double Queen

2 Double bed
Non-smoking
Air conditioning
Private bathroom
Refrigerator
Toothbrushes
Room Details
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6

Deluxe King Room

1 King bed
Non-smoking
Air conditioning
Private bathroom
Refrigerator
Towels
Room Details
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4

Deluxe King Suite

1 King bed
Non-smoking
Wi-Fi in room
Smart door lock
Room Details
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5

Deluxe Double Queen

2 Double bed
Non-smoking
Air conditioning
Private bathroom
Refrigerator
Toothbrushes
Room Details
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5

Luxury King Suite

1 King bed
Non-smoking
Towels
Blackout curtains
Shower with grab bars
Bedding: Blanket or quilt
Room Details
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4

Loft Double Queen

2 Double bed
Non-smoking
Wi-Fi in room
Smart door lock
Bathtub or shower
Room Details
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5

Deluxe King Room-Accessible

1 King bed
Non-smoking
Air conditioning
Private bathroom
Refrigerator
Toothbrushes
Room Details
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3

Bunk Room

1 Bunk bed
Non-smoking
Air conditioning
Private bathroom
Refrigerator
Towels
Room Details
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3

Corner King Room

1 King bed
Non-smoking
Wi-Fi in room
Smart door lock
Bathtub or shower
Room Details
Check Availability
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Average for similar properties in St. Louis
Guest User
April 14, 2026
i love this place! while things are clean, food is delicious, museum beautiful, and swim and gym clubs really great, this place shines because of its staff :) they are so kind and i always feel SO welcome!!
Nene Newin
November 9, 2025
Love it a lot. I even extended my stay. The breakfast is also very yummmm!
Guest User
April 14, 2025
This is a very nice hotel with a good location. It was very clean although in the bathroom the painters left splashes of paint on the floor and in the shower. Plus all of us said there was a coffee machine in the rooms with coffee but no cups so you had to go downstairs and purchase coffee. It’s a pricey hotel but we would stay again. The museum upstairs is very nice.
Guest User
December 9, 2024
20 mins walk to the Arch. Old building refreshed into a new hotel. The gym and pool is modern and new. A bit noisy at the lobby at nights.
Juanita Lawrence
November 19, 2025
It was a nice place to stay
Guest User
November 3, 2023
Location in proximity to city attractions is amazing 5/5. Location in terms of safety is 2/5. There isn’t a covered secured lot for your car and I was approached by many people asking me for money while taking a walk around the building. Service is hit or miss. When I arrived, and attempted to open my car door, I was accosted by the valet who yelled at me and asked me what I was TRYING to do. I told him I was checking in to the hotel. And he was aggressively unpleasant, seemingly angry that I had arrived. Conversely, the valet attendant the next day was polite and wonderful. The front desk was nice but did not review any of the amenities nor offer any information about the hotel, which is a shame. Nice but inattentive and uninterested. The service at both Idol Wolf and Good Press were 5/5. The food at both were 5/5. The hotel itself is gorgeous. There’s art set in an old gym. The renovation is well done. Enjoyed it very much. The view from the room was also very nice. The room itself was standard with a few attention to detail things needing addressed. Such as broken handles and non working bathroom fixtures. Overall would recommend this hotel because it is unique. Big plus - they allow pets!!! Yes!
Guest User
October 31, 2023
This is my 3rd 21c I’ve stayed at and my favorite so far! Everything was lovely and charming and Idol Wolf, the restaurant, was superb! Thank you for a fantastic weekend!
Guest User
October 25, 2023
We had to make an unexpected trip to St. Louis and stayed at 21C because we appreciate the concept and the location was convenient. It was beyond amazing. The food and drinks were exceptional. The staff from all departments were very friendly. Definitely will recommend. A++
Guest User
June 17, 2024
Location is not good..

Services & Amenities

Restaurant
No additional info available

Property Policies

Check-in and Check-out Times
Check-in: 16:00–02:00 the next day
Check-out: Before 11:00

Front desk hours: 24/7

Child policies
Children of all ages are welcome at this property.
Additional fees may be charged for children using existing beds. Add the number of children to get a more accurate price.

Cribs and Extra Beds
Extra bed and crib policies may vary according to room type. Please refer to the room type details for more information.

Breakfast
StyleA la carte
Opening hours[Mon - Sun] 06:30-13:00 Open
AgeFee
Adult
Contact property
Additional breakfast fees are not included in the total and need to be paid at the property.

Pets
Pets are allowed

Age Requirements
The main guest checking in must be at least 18 years old

Paying at the hotel

Property Description

Local hotel name: 21C Museum Hotel St Louis
  • Opened: 2023
  • Number of Rooms: 173
Phone:+1-314-9402333
Email:stl.sales@21chotels.com
Located in the heart of downtown St. Louis, and a short walk from the City Museum and CITYPARK stadium, 21c Museum Hotel St. Louis includes a 173-room boutique hotel, contemporary art museum, Idol Wolf restaurant, Good Press café, and Locust Street Athletic and Swim Club, a full-service wellness center. With more than 14,000 square feet of exhibition and meeting & event space seamlessly integrated into all areas of the property, there are opportunities to discover contemporary art around every corner.

You might be wondering

What are the check-in and check-out times at 21C Museum Hotel St Louis?

Check-in time at 21C Museum Hotel St Louis starts at 16:00-02:00, and check-out time is by 11:00.

Does 21C Museum Hotel St Louis have a pool?

Yes, 21C Museum Hotel St Louis has a swimming pool for guests.

Are pets allowed at 21C Museum Hotel St Louis?

Yes, pets are welcome at 21C Museum Hotel St Louis, but we recommend calling ahead to confirm details (e.g., pet size, fees).

How much does it cost to stay at 21C Museum Hotel St Louis?

Room prices at 21C Museum Hotel St Louis vary by travel dates, hotel policy, and other factors. Enter your travel dates to see current prices.

How to get to 21C Museum Hotel St Louis from the nearest airport?

The nearest airport is St. Louis Lambert International Airport, located about 28 mins from hotel by car (30.9 km) away.

What’s the cancellation policy at 21C Museum Hotel St Louis?

The cancellation policy at 21C Museum Hotel St Louis depends on your room type and booking terms.

About This Property

Nearest AirportSt. Louis Lambert International Airport
Distance to Airport30.93KM
Nearest Train StationUnion Station
Distance to Train Station0.89KM
Average Price FromUSD275
Hotel Star Rating4