Holiday Inn Express & Suites ST. Louis South - I-55
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Holiday Inn Express & Suites ST. Louis South - I-55
4250 Midamerica Ln, St. Louis, Missouri, 63129, United States
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Highlights
Delicious breakfast
Ideal location
Lots to do
Free parkingAmenities
Public parkingFree
Gym
24-hour front desk
Wake-up call
Wi-Fi in public areas
Smoking area
Conference room
Multi-function room
All amenities
Property Description
Welcome to the new Holiday Inn Express & Suites St. Louis South I-55!
South St. Louis's newest and most modern Holiday Inn Express Hotel nestled within a growing development at the intersection of Butler Hill Road & I-55 just one mile south of I-270/255 with access to everything St. Louis has to offer. The hotel is just 14 miles directly south of Downtown St. Louis and located at exit #195 from I-55.
Business travelers will benefit from our central location with easy on/off access to I-55 that offers access to the different areas of St. Louis within minutes. The hotel complex includes the Barnes-Jewish Siteman Cancer Center & Mercy Health. We are just minutes from Metlife, Anhueser Busch, Cigna and the National Cemetary Association.
Our non smoking Holiday Inn Express & Suites St. Louis I-55 hotel is very convenient to guests visiting Busch Stadium, Gateway Arch, Grant's Farm, Magic House, St. Louis Science Center, St. Louis Zoo, Forest Park, River City Casino and much more!
Hotel Guests can enjoy an array of amenities including guest room suites, Indoor Pool, Suite Shop, Two Meeting Rooms, Complimentary Express Start Breakfast, Complimentary High Speed Wired & Wireless Internet, Comfortable Great Room with Outdoor Patio and warm Cookies & Milk served nightly.
Guests will enjoy our midwest hospitality in South St. Louis. Our goal is to make every guest feel at home so that we exceed all of their expectations!
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9.3/10
The staff were so supportive and location is near to highway .
All 104 reviews
Surroundings
Airport: St. Louis Lambert International Airport
(45.2 km)
Train: Kirkwood Station
(17.4 km)
Train: Shrewsbury-Lansdowne I-44
(18.5 km)
Landmarks: Abiding Savior Lutheran Church
(540m)
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Overview
Rooms
Guest Reviews
Services & Amenities
Policies
5
Standard Room with Two Queen Beds
2 Queen bed
Free wired Internet
Non-smoking
Air conditioning
Refrigerator
Towels
Microwave
Check Availability
6
Comm Acc Standard King Room with Bath Shower Combo
1 King bed
Has window
Free wired Internet
Non-smoking
Air conditioning
Private bathroom
Bathtub
Refrigerator
Check Availability
5
Suite With 1 King Bed, Extra Living, Walk-in Shower
1 King bed
Free wired Internet
Non-smoking
Air conditioning
Private bathroom
Refrigerator
TV
Check Availability
6
Standard Room With 1 King Bed And Bath Shower Combination
1 King bed
Free wired Internet
Non-smoking
Air conditioning
Private bathroom
Refrigerator
TV
Check Availability
5
Mobil Acc King Suite with Tub
1 King bed
Has window
Free wired Internet
Non-smoking
Air conditioning
Private bathroom
Bathtub
Refrigerator
Check Availability
5
Standard King Room With Mobility Accessible Roll-in Shower
1 King bed
Free wired Internet
Non-smoking
Air conditioning
Refrigerator
Towels
Microwave
Check Availability
5
Comm Acc Standard Two Queen Room with Bath Shower Combo
2 Queen bed
Has window
Free wired Internet
Non-smoking
Air conditioning
Private bathroom
Refrigerator
TV
Check Availability
3
Standard Room
Free wired Internet
Non-smoking
Air conditioning
Refrigerator
Towels
Microwave
Check Availability
6
Standard Room With 2 Queen Beds And Mobility Accessible Tub
2 Queen bed
Free wired Internet
Non-smoking
Air conditioning
Private bathroom
Refrigerator
TV
Check Availability
8
One-Bedroom Suite With 2 Queen Beds And Extra Living Area
2 Queen bed
Free wired Internet
Non-smoking
Air conditioning
Private bathroom
Refrigerator
TV
Check Availability
Hide Room Types
Guest Reviews
9.3/10
Great
104 reviews
- Cleanliness9.4
- Amenities9.3
- Location9.2
- Service9.3
Average for similar properties in St. Louis

Review summary
Powered by AI
Location: Near to highway and highway exit, convenient(based on 1 review)
Traveler 1
May 17, 2025
The staff were so supportive and location is near to highway .
Guest User
December 5, 2024
Everything was good
Little far from down town
Guest User
October 21, 2024
Always good.
1380586****
December 18, 2024
高速出口
方便
酒店較新
Translate
Berta
July 12, 2025
I was in a convention in St Louis, I stayed at this hotel and it was so convenient going in hwy. The place is clean and upgraded front desk vey helpful.
Craig
July 4, 2025
Best stay
The staff was so very kind. I had broken my leg and they offered to get me a wheel chair and take me to my room. They were very helpful at breakfast and when we needed an extra pillow. They even had cookie hour every night with warm cookies and cold milk!
Joe
June 26, 2025
Wow. They deserve their high rating. Staff was very attentive and worked to get me into a new room when we had an issue with the shower door. High wear equipment will eventually break, and it was barely an inconvenience. They even offered to move my luggage for me. Great walk in shower with good pressure, great breakfast that went fast but was quickly restocked, and a clean room.
Jon
June 25, 2025
Ok visit
Could have been better. Indoor pool a bit small. The staff did not come by and change bedding or towels
Services & Amenities
Most popular amenities
Public parking
Free
Gym
24-hour front desk
Wake-up call
Wi-Fi in public areas
Smoking area
Conference room
Additional charge
Multi-function room
Business center
Fax/copying service
Additional charge
Gym
Conference room
More Amenities
Internet
Wi-Fi in public areas
Indoor swimming pool
Heated pool
Parking
Public (not only for guests) is available On-site parking. Reservation not needed.
Public parking
Free
Front desk services
24-hour front desk
Safe at front desk
Wake-up call
Languages spoken
English
Health & wellness
Gym
Public areas
No smoking in public areas
Smoking area
Elevator
Vending machines
Facilities for children
Children's meals available
Business services
Multi-function room
Conference room
Additional charge
Fax/copying service
Additional charge
Business center
Accessibility
Accessible rooms available
Pool ramp available
Stair-free main entrance
Safety & security
First aid kit
Intruder alarm
Smoke detector
Fire extinguisher
CCTV in public areas
First aid room
Property Policies
Check-in and Check-out Times
Check-in: after 15:00
Check-out: Before 11:00
Front desk hours: 24/7
Child policies
Children of all ages are welcome at this property.
Additional fees may be charged for children using existing beds. Add the number of children to get a more accurate price.
Cribs and Extra Beds
Extra bed and crib policies may vary according to room type. Please refer to the room type details for more information.
Breakfast
StyleBuffet
Opening hours[Mon - Sun] 06:00-09:30 Open
| Age | Fee |
|---|---|
Adult | Contact property |
Additional breakfast fees are not included in the total and need to be paid at the property.
Pets
Pets are not allowed
Service animals
Service animals are allowed
Age Requirements
The main guest checking in must be at least 21 years old
Paying at the hotel





- Cash
Property Description
- Opened: 2017
- Number of Rooms: 104
Phone:+1-314-8940700
Email:stlml@midamcorp.com
Welcome to the new Holiday Inn Express & Suites St. Louis South I-55!
South St. Louis's newest and most modern Holiday Inn Express Hotel nestled within a growing development at the intersection of Butler Hill Road & I-55 just one mile south of I-270/255 with access to everything St. Louis has to offer. The hotel is just 14 miles directly south of Downtown St. Louis and located at exit #195 from I-55.
Business travelers will benefit from our central location with easy on/off access to I-55 that offers access to the different areas of St. Louis within minutes. The hotel complex includes the Barnes-Jewish Siteman Cancer Center & Mercy Health. We are just minutes from Metlife, Anhueser Busch, Cigna and the National Cemetary Association.
Our non smoking Holiday Inn Express & Suites St. Louis I-55 hotel is very convenient to guests visiting Busch Stadium, Gateway Arch, Grant's Farm, Magic House, St. Louis Science Center, St. Louis Zoo, Forest Park, River City Casino and much more!
Hotel Guests can enjoy an array of amenities including guest room suites, Indoor Pool, Suite Shop, Two Meeting Rooms, Complimentary Express Start Breakfast, Complimentary High Speed Wired & Wireless Internet, Comfortable Great Room with Outdoor Patio and warm Cookies & Milk served nightly.
Guests will enjoy our midwest hospitality in South St. Louis. Our goal is to make every guest feel at home so that we exceed all of their expectations!
Frequently Asked Questions
What are the check-in and check-out times at Holiday Inn Express & Suites ST. Louis South - I-55?
Check-in time at Holiday Inn Express & Suites ST. Louis South - I-55 starts at 15:00, and check-out time is by 11:00.What are the check-in and check-out times at Holiday Inn Express & Suites ST. Louis South - I-55?
Does Holiday Inn Express & Suites ST. Louis South - I-55 have a pool?
Yes, Holiday Inn Express & Suites ST. Louis South - I-55 has a swimming pool for guests.Does Holiday Inn Express & Suites ST. Louis South - I-55 have a pool?
Are pets allowed at Holiday Inn Express & Suites ST. Louis South - I-55?
No, pets are not allowed at Holiday Inn Express & Suites ST. Louis South - I-55.Are pets allowed at Holiday Inn Express & Suites ST. Louis South - I-55?
How much does it cost to stay at Holiday Inn Express & Suites ST. Louis South - I-55?
Room prices at Holiday Inn Express & Suites ST. Louis South - I-55 vary by travel dates, hotel policy, and other factors. Enter your travel dates to see current prices.How much does it cost to stay at Holiday Inn Express & Suites ST. Louis South - I-55?
How to get to Holiday Inn Express & Suites ST. Louis South - I-55 from the nearest airport?
The nearest airport is St. Louis Lambert International Airport, located about 32 mins from hotel by car (45.2 km) away.How to get to Holiday Inn Express & Suites ST. Louis South - I-55 from the nearest airport?
What’s the cancellation policy at Holiday Inn Express & Suites ST. Louis South - I-55?
The cancellation policy at Holiday Inn Express & Suites ST. Louis South - I-55 depends on your room type and booking terms.What’s the cancellation policy at Holiday Inn Express & Suites ST. Louis South - I-55?
About This Property
| Nearest Airport | St. Louis Lambert International Airport |
|---|---|
| Distance to Airport | 45.21KM |
| Nearest Train Station | Kirkwood Station |
| Distance to Train Station | 17.35KM |
| Average Price From | USD177 |
| Hotel Star Rating | 2 |









