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Madrid Barajas Airport to Santiago Del Estero Airport flight

Explore the cheapest one-way and round-trip flights from Madrid Barajas Airport to Santiago Del Estero Airport over the next 90 days, with one-way fares from US$1,252 and round-trip from US$1,195. Based on Trip.com's latest 7-day flight data.

      • MAD 09:55
        35h 40m
        1 stop
        SDE 17:35
        Madrid - Santiago del Estero | Fri, Dec 4 | Aerolineas Argentinas
        SDE 18:05
        18h 5m
        1 stop
        MAD 16:10
        Santiago del Estero - Madrid | Sat, Dec 12 | Aerolineas Argentinas
        US$1,195 US$3,858
        69% off
        69% off
        US$3,858 US$1,195
      • MAD 20:05
        30h
        1 stop
        SDE 21:05
        Madrid - Santiago del Estero | Tue, Oct 13 | Aerolineas Argentinas
        SDE 18:05
        18h 5m
        1 stop
        MAD 17:10
        Santiago del Estero - Madrid | Sat, Oct 17 | Aerolineas Argentinas
        US$1,655 US$3,858
        56% off
        56% off
        US$3,858 US$1,655
      • MAD 22:15
        26h 50m
        1 stop
        SDE 21:05
        Madrid - Santiago del Estero | Mon, Nov 9 | Aerolineas Argentinas
        SDE 18:05
        33h 15m
        1 stop
        MAD 07:20
        Santiago del Estero - Madrid | Sat, Nov 14 | Aerolineas Argentinas
        US$1,677 US$3,858
        56% off
        56% off
        US$3,858 US$1,677
      • MAD 23:55
        21h 40m
        1 stop
        SDE 17:35
        Madrid - Santiago del Estero | Fri, Dec 4 | Air Europa
        SDE 18:05
        18h 5m
        1 stop
        MAD 16:10
        Santiago del Estero - Madrid | Sat, Dec 12 | Aerolineas Argentinas
        US$1,713
        56% off
        US$3,858 US$1,713
      • MAD 23:59
        21h 36m
        1 stop
        SDE 17:35
        Madrid - Santiago del Estero | Fri, Dec 4 | Iberia
        SDE 18:05
        18h 5m
        1 stop
        MAD 16:10
        Santiago del Estero - Madrid | Sat, Dec 12 | Aerolineas Argentinas
        US$1,876
        51% off
        US$3,858 US$1,876
      • MAD 10:55
        27h 15m
        1 stop
        SDE 09:10
        Madrid - Santiago del Estero | Mon, Oct 19 | Aerolineas Argentinas
        SDE 11:00
        25h 10m
        1 stop
        MAD 17:10
        Santiago del Estero - Madrid | Fri, Oct 23 | Aerolineas Argentinas
        US$2,197
        43% off
        US$3,858 US$2,197
      • MAD 19:05
        30h
        1 stop
        SDE 21:05
        Madrid - Santiago del Estero | Tue, Oct 27 | Aerolineas Argentinas
        SDE 11:00
        25h 10m
        1 stop
        MAD 16:10
        Santiago del Estero - Madrid | Mon, Nov 2 | Aerolineas Argentinas
        US$2,246
        42% off
        US$3,858 US$2,246
      • MAD 08:45
        29h 30m
        1 stop
        SDE 09:15
        Madrid - Santiago del Estero | Tue, Oct 13 | Iberia
        SDE 18:05
        15h 30m
        1 stop
        MAD 14:35
        Santiago del Estero - Madrid | Sat, Oct 17 | Aerolineas Argentinas
        US$2,341
        39% off
        US$3,858 US$2,341
      • MAD 23:55
        26h 10m
        1 stop
        SDE 21:05
        Madrid - Santiago del Estero | Tue, Oct 13 | Air Europa
        SDE 18:05
        30h 5m
        1 stop
        MAD 05:10
        Santiago del Estero - Madrid | Sat, Oct 17 | Aerolineas Argentinas
        US$2,622
        32% off
        US$3,858 US$2,622
      • MAD 23:55
        25h 10m
        1 stop
        SDE 21:05
        Madrid - Santiago del Estero | Tue, Oct 27 | Air Europa
        SDE 11:00
        25h 10m
        1 stop
        MAD 16:10
        Santiago del Estero - Madrid | Mon, Nov 2 | Aerolineas Argentinas
        US$3,510
        9% off
        US$3,858 US$3,510
      • MAD 13:00
        17h 25m
        1 stop
        SDE 14:00
        Madrid - Santiago del Estero | Sun, Oct 11 | Normal Airline
        SDE 15:00
        6h
        Nonstop
        MAD 16:00
        Santiago del Estero - Madrid | Tue, Oct 13 | Normal Airline
        More cheap flights
        More cheap flights
      • MAD 10:55
        35h 40m
        1 stop
        SDE 17:35
        Madrid - Santiago del Estero | Mon, Oct 12 | Aerolineas Argentinas
        US$1,252 US$2,279
        45% off
        45% off
        US$2,279 US$1,252
      • MAD 10:55
        27h 10m
        1 stop
        SDE 09:05
        Madrid - Santiago del Estero | Fri, Oct 30 | Aerolineas Argentinas
        US$1,319 US$2,279
        42% off
        42% off
        US$2,279 US$1,319
      • MAD 09:55
        27h 5m
        1 stop
        SDE 09:00
        Madrid - Santiago del Estero | Thu, Nov 12 | Aerolineas Argentinas
        US$1,346 US$2,279
        41% off
        41% off
        US$2,279 US$1,346
      • MAD 10:55
        27h 15m
        1 stop
        SDE 09:10
        Madrid - Santiago del Estero | Thu, Oct 29 | Aerolineas Argentinas
        US$1,366
        40% off
        US$2,279 US$1,366
      • MAD 19:05
        30h
        1 stop
        SDE 21:05
        Madrid - Santiago del Estero | Fri, Nov 13 | Aerolineas Argentinas
        US$1,403
        38% off
        US$2,279 US$1,403
      • MAD 20:05
        25h 35m
        1 stop
        SDE 16:40
        Madrid - Santiago del Estero | Sat, Oct 10 | Aerolineas Argentinas
        US$1,603
        30% off
        US$2,279 US$1,603
      • MAD 10:55
        28h 25m
        1 stop
        SDE 10:20
        Madrid - Santiago del Estero | Wed, Oct 28 | Aerolineas Argentinas
        US$1,604
        30% off
        US$2,279 US$1,604
      • MAD 22:15
        27h
        1 stop
        SDE 21:15
        Madrid - Santiago del Estero | Sun, Nov 15 | Aerolineas Argentinas
        US$1,615
        28% off
        US$2,279 US$1,615
      • MAD 23:55
        26h 10m
        1 stop
        SDE 21:05
        Madrid - Santiago del Estero | Thu, Oct 29 | Air Europa
        US$1,703
        25% off
        US$2,279 US$1,703
      • MAD 00:05
        37h 55m
        1 stop
        SDE 09:00
        Madrid - Santiago del Estero | Sat, Oct 10 | Iberia
        US$1,848
        19% off
        US$2,279 US$1,848
      • MAD 23:55
        38h 15m
        1 stop
        SDE 09:10
        Madrid - Santiago del Estero | Wed, Oct 28 | Air Europa
        US$2,059
        10% off
        US$2,279 US$2,059
      • MAD 20:05
        19h 15m
        1 stop
        SDE 10:20
        Madrid - Santiago del Estero | Sun, Oct 18 | Aerolineas Argentinas
        US$2,073
        9% off
        US$2,279 US$2,073
      • MAD 13:00
        17h 25m
        1 stop
        SDE 14:00
        Madrid - Santiago del Estero | Sun, Oct 11 | Normal Airline
        More cheap flights
        More cheap flights

Displayed flight fares from Madrid Barajas Airport to Santiago Del Estero Airport are based on average prices across airlines for the next 3 months, according to the latest Trip.com database.

Which airline offers the cheapest flights from Madrid Barajas Airport to Santiago Del Estero Airport?

The cheapest airline flying from Madrid Barajas Airport to Santiago Del Estero Airport is Air China (from US$885) among 10 carriers operating this route. Based on Trip.com's latest 7-day flight data.

Air China
From US$885
Aerolineas Argentinas
From US$914
Air Europa
From US$1,066
Boliviana De Aviación
From US$1,068
Azul Airlines
From US$1,098
Iberia
From US$1,211
American Airlines
From US$1,264
LATAM Airlines
From US$1,278
avianca
From US$1,345
Swiss Airlines
From US$1,841

Find more flights and airlines

What is the flight schedule from Madrid Barajas Airport to Santiago Del Estero Airport?

Check on the flight schedule from Madrid to Santiago del Estero to find the flight that matches your travel plan.

Flight info.
Departure
Arrival
Weekly Schedule

  1. IB103

    Madrid Barajas Airport

    23:59

    MAD

    12h 41m

    Nonstop

    08:40

    EZE

    S M T W T F S
    Search

  2. AR1460

    Jorge Newbery Airport

    08:10

    AEP

    1h 50m

    Nonstop

    10:00

    SDE

    S M T W T F -

  3. UX041

    Madrid Barajas Airport

    23:55

    MAD

    12h 50m

    Nonstop

    07:45

    EZE

    S M T W T F S
    Search

  4. AR1460

    Jorge Newbery Airport

    08:10

    AEP

    1h 50m

    Nonstop

    10:00

    SDE

    S M T W T F -

  5. LA8075

    Madrid Barajas Airport

    14:45

    MAD

    10h 35m

    Nonstop

    20:20

    GRU

    S - T W T F S
    Search

  6. LA8130

    São Paulo/Guarulhos–Governor André Franco Montoro International Airport

    22:00

    GRU

    3h 5m

    Nonstop

    01:05

    EZE

    S M T W T F S

  7. AR1460

    Jorge Newbery Airport

    08:10

    AEP

    1h 50m

    Nonstop

    10:00

    SDE

    S M T W T F -

  8. LA2485

    Madrid Barajas Airport

    01:45

    MAD

    11h 45m

    Nonstop

    06:30

    LIM

    S - T - T F S
    Search

  9. LA2380

    Jorge Chávez International Airport

    09:35

    LIM

    4h 25m

    Nonstop

    16:00

    AEP

    S M T W T F S

  10. AR1464

    Jorge Newbery Airport

    14:50

    AEP

    1h 50m

    Nonstop

    16:40

    SDE

    S M T W T - S

  11. IB103

    Madrid Barajas Airport

    23:59

    MAD

    12h 41m

    Nonstop

    08:40

    EZE

    S M T W T F S
    Search

  12. AR1464

    Jorge Newbery Airport

    14:50

    AEP

    1h 50m

    Nonstop

    16:40

    SDE

    S M T W T - S

  13. UX041

    Madrid Barajas Airport

    23:55

    MAD

    12h 50m

    Nonstop

    07:45

    EZE

    S M T W T F S
    Search

  14. AR1464

    Jorge Newbery Airport

    14:50

    AEP

    1h 50m

    Nonstop

    16:40

    SDE

    S M T W T - S

  15. UX057

    Madrid Barajas Airport

    23:55

    MAD

    9h 30m

    Nonstop

    05:25

    GRU

    S M T W T F S
    Search

  16. AR1243

    São Paulo/Guarulhos–Governor André Franco Montoro International Airport

    10:20

    GRU

    3h

    Nonstop

    13:20

    AEP

    S M T W T F S

  17. AR1464

    Jorge Newbery Airport

    14:50

    AEP

    1h 50m

    Nonstop

    16:40

    SDE

    S M T W T - S

  18. LA715

    Madrid Barajas Airport

    22:45

    MAD

    10h 45m

    Nonstop

    05:30

    GRU

    S M T W T F S
    Search

  19. LA8192

    São Paulo/Guarulhos–Governor André Franco Montoro International Airport

    07:25

    GRU

    3h 5m

    Nonstop

    10:30

    AEP

    S M T W T F S

  20. AR1464

    Jorge Newbery Airport

    14:50

    AEP

    1h 50m

    Nonstop

    16:40

    SDE

    S M T W T - S

  21. CA897

    Madrid Barajas Airport

    23:15

    MAD

    10h 45m

    Nonstop

    05:00

    GRU

    S - T W - - S
    Search

  22. LA8192

    São Paulo/Guarulhos–Governor André Franco Montoro International Airport

    07:25

    GRU

    3h 5m

    Nonstop

    10:30

    AEP

    S M T W T F S

  23. AR1464

    Jorge Newbery Airport

    14:50

    AEP

    1h 50m

    Nonstop

    16:40

    SDE

    S M T W T - S

  24. CA897

    Madrid Barajas Airport

    23:15

    MAD

    10h 45m

    Nonstop

    05:00

    GRU

    S - T W - - S
    Search

  25. AR1243

    São Paulo/Guarulhos–Governor André Franco Montoro International Airport

    10:20

    GRU

    3h

    Nonstop

    13:20

    AEP

    S M T W T F S

  26. AR1464

    Jorge Newbery Airport

    14:50

    AEP

    1h 50m

    Nonstop

    16:40

    SDE

    S M T W T - S
Find more flights and airlines

About Madrid Barajas Airport and Santiago Del Estero Airport

Learn about Madrid Barajas Airport (MAD) and Santiago Del Estero Airport (SDE) — including location, terminals, transportation, and travel tips.

Flight distance 9,850.53 km
Cheapest one-way ticket price US$1,252
Cheapest return ticket price US$1,195

FAQs for Madrid Barajas Airport to Santiago Del Estero Airport Flights

  • What is the transportation method from the main airport to downtown in Santiago del Estero?

    • The distance from Santiago Del Estero Airport to downtown is about 4 km, by taxi about 20 minutes.
  • One-way flights from Madrid Barajas Airport to Santiago Del Estero Airport currently start from US$1,252, and round-trip fares start from US$1,195. The current lowest fare is a Aerolineas Argentinas flight departing on Mon, Oct 12; prices may vary depending on availability.
  • Based on Trip.com flight data for departures within the next 30 days with at most one stop, the average one-way price from Madrid Barajas Airport to Santiago Del Estero Airport is US$2,101. Prices may vary depending on the departure date, airline, and availability.
  • Enter Madrid Barajas Airport and Santiago Del Estero Airport, select your departure date and number of passengers, then compare flights by price, flight duration, and baggage allowance. Once you've chosen a fare, review the change and refund rules, fill in passenger details, and pay to receive your booking confirmation.

Popular Destinations

Note: Prices shown on this page are the estimated lowest prices found in the last 24 hours and include all taxes and fees.

Book with no extra fees

Prices displayed on this page are all-inclusive (incl. taxes, fuel surcharges, Civil Aviation Development Fund, etc.), and all fees are clearly shown before you pay. Charges for checked baggage, onboard meals, Wi‑Fi, and other optional services are also included where applicable in the flight cards.

Real-time pricing updates

Prices, availability, and travel details on this page have been updated within the last 24 hours, and for many routes are refreshed in real time. The more popular the route, the more accurate and up-to-date the data.

Change & Cancellation Policy

Trip.com shows the change and cancellation rules for each ticket during the booking process, including all related fees and conditions. Please refer to the following scenarios:
Voluntary cancellation/change:
To request a change or cancellation, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and flight segment, and submit your request. Please note that additional charges may apply based on the airline’s fare rules.
Cancellation/change due to a flight schedule change:
If your flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For full details of change and cancellation policies, please refer to the customer support pages.