Hotels in Lake City

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24 Best Hotels in Lake City

Find great hotels in Lake City on Trip.com! Check guest reviews, latest prices and hotel details to pick your perfect stay.
Top Picks
Lowest Price
Closest to Downtown
Top Reviewed
La Quinta by Wyndham Lake City Hotels in Lake City
La Quinta by Wyndham Lake City Hotels in Lake CityLa Quinta by Wyndham Lake City Hotels in Lake CityLa Quinta by Wyndham Lake City Hotels in Lake CityLa Quinta by Wyndham Lake City Hotels in Lake CityLa Quinta by Wyndham Lake City Hotels in Lake CityLa Quinta by Wyndham Lake City Hotels in Lake City
21
Hotels in Lake City
Public parking
Gym
Luggage storage
+2
"It's good for dog breeders to go. When you ask for a room, ask for a room where there are no animals as much as possible."
Very Good
102 reviews
8.5/10
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Knights Inn Lake City Hotels in Lake City
Knights Inn Lake City Hotels in Lake CityKnights Inn Lake City Hotels in Lake CityKnights Inn Lake City Hotels in Lake CityKnights Inn Lake City Hotels in Lake CityKnights Inn Lake City Hotels in Lake CityKnights Inn Lake City Hotels in Lake City
11
Hotels in Lake City
Parking
Wi-Fi in public areas
"Yeah, I've been to that hotel twice, and I love it—the people are very kind, humble, and helpful. I would definitely go back again."
88 reviews
5.5/10
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Best Western Plus Lake City Hotels in Lake City
Best Western Plus Lake City Hotels in Lake CityBest Western Plus Lake City Hotels in Lake CityBest Western Plus Lake City Hotels in Lake CityBest Western Plus Lake City Hotels in Lake CityBest Western Plus Lake City Hotels in Lake CityBest Western Plus Lake City Hotels in Lake City
60
Hotels in Lake City
Gym
停车场
Business center
+4
"Best place. Great people, locations and awesome breakfast. Tammy is exceptional from breakfast. Just a pleasure being at this hotel. They understand hospitality."
Very Good
106 reviews
8.8/10
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Comfort Suites Lake City Hotels in Lake City
Comfort Suites Lake City Hotels in Lake CityComfort Suites Lake City Hotels in Lake CityComfort Suites Lake City Hotels in Lake CityComfort Suites Lake City Hotels in Lake CityComfort Suites Lake City Hotels in Lake CityComfort Suites Lake City Hotels in Lake City
50
Hotels in Lake City
Private parking
Gym
Wake-up call
+6
"Just stayed fir 1 night but everything was great. Clean room, comfortable bed, workout room, hot breakfast. And everyone was so nice and accommodating."
Great
102 reviews
9.2/10
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Courtyard Lake City Hotels in Lake City
Courtyard Lake City Hotels in Lake CityCourtyard Lake City Hotels in Lake CityCourtyard Lake City Hotels in Lake CityCourtyard Lake City Hotels in Lake CityCourtyard Lake City Hotels in Lake CityCourtyard Lake City Hotels in Lake City
86
Hotels in Lake City
Gym
Luggage storage
Restaurant
+2
"Tappa intermedia di un Road trip, hotel nuovissimo, pulito e con letto comodo, quello che avevo bisogno dopo 6 ore di autostrada"
Amazing
75 reviews
9.4/10
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Gateway Inn Hotels in Lake City
Gateway Inn Hotels in Lake CityGateway Inn Hotels in Lake CityGateway Inn Hotels in Lake CityGateway Inn Hotels in Lake CityGateway Inn Hotels in Lake CityGateway Inn Hotels in Lake City
46
Hotels in Lake City
Parking
Wi-Fi in public areas
Smoking area
Located in Lake City, Gateway Inn is within a 5-minute drive of Lake Shore Primary Care West and Regal UA Cinema 90. This motel is 0.9 mi (1.4 km) from Lake City Medical Center and 0.9 mi (1.4 km) from Fresenius Medical Care at Lake City Medical Center. This motel offers designated smoking areas. Featured amenities include a 24-hour front desk, laundry facilities, and a vending machine. Free self parking is available onsite. Make yourself at home in one of the 50 air-conditioned rooms featuring microwaves and LCD televisions. Complimentary wireless internet access is available to keep you connected.
Good
76 reviews
7.8/10
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Americas Best Value Inn Lake City Hotels in Lake City
Americas Best Value Inn Lake City Hotels in Lake CityAmericas Best Value Inn Lake City Hotels in Lake CityAmericas Best Value Inn Lake City Hotels in Lake CityAmericas Best Value Inn Lake City Hotels in Lake CityAmericas Best Value Inn Lake City Hotels in Lake CityAmericas Best Value Inn Lake City Hotels in Lake City
49
Hotels in Lake City
Public parking
Wi-Fi in public areas
Smoking area
+1
"Traveling can be."
Very Good
103 reviews
8.3/10
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Tru by Hilton Lake City Hotels in Lake City
Tru by Hilton Lake City Hotels in Lake CityTru by Hilton Lake City Hotels in Lake CityTru by Hilton Lake City Hotels in Lake CityTru by Hilton Lake City Hotels in Lake CityTru by Hilton Lake City Hotels in Lake CityTru by Hilton Lake City Hotels in Lake City
95
Hotels in Lake City
Outdoor swimming pool
Gym
Public parking
+5
"Amazing, clean nice"
Great
97 reviews
9.2/10
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Econo Lodge Lake City-North Hotels in Lake City
Econo Lodge Lake City-North Hotels in Lake CityEcono Lodge Lake City-North Hotels in Lake CityEcono Lodge Lake City-North Hotels in Lake CityEcono Lodge Lake City-North Hotels in Lake CityEcono Lodge Lake City-North Hotels in Lake CityEcono Lodge Lake City-North Hotels in Lake City
46
Hotels in Lake City
Public parking
Wake-up call
Wi-Fi in public areas
+1
A stay at Econo Lodge Lake City-North places you in the heart of Lake City, within a 15-minute walk of Fresenius Medical Care at Lake City Medical Center and Lake City Medical Center. This hotel is 0.9 mi (1.5 km) from Regal UA Cinema 90 and 1.2 mi (1.9 km) from Lake City Mall. Enjoy recreation amenities such as an outdoor pool or take in the view from a garden. This hotel also features complimentary wireless internet access, a picnic area, and a vending machine. A complimentary continental breakfast is served daily from 6:00 AM to 9:00 AM. Featured amenities include a 24-hour front desk, laundry facilities, and a water dispenser. Free self parking is available onsite. Stay in one of 61 guestrooms featuring LED televisions. Complimentary wired and wireless internet access keeps you connected, and satellite programming provides entertainment. Bathrooms have shower/tub combinations and hair dryers. Conveniences include coffee/tea makers and irons/ironing boards, as well as phones with free local calls.
43 reviews
6.6/10
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Holiday Inn & Suites LAKE CITY by IHG Hotels in Lake City
Holiday Inn & Suites LAKE CITY by IHG Hotels in Lake CityHoliday Inn & Suites LAKE CITY by IHG Hotels in Lake CityHoliday Inn & Suites LAKE CITY by IHG Hotels in Lake CityHoliday Inn & Suites LAKE CITY by IHG Hotels in Lake CityHoliday Inn & Suites LAKE CITY by IHG Hotels in Lake CityHoliday Inn & Suites LAKE CITY by IHG Hotels in Lake City
42
Hotels in Lake City
Golf course
Indoor swimming pool
Gym
+8
"Good location, close to the highway exit. Good service attitude. Large parking lot. Breakfast is a meal, there are many types, you can choose one of them. We choose eggs, bacon, vegetables, pasta, fried potatoes, cheese. I did n’t want any other beverages, I just took the milk and took it back to the room to heat it with a microwave. There was enough breakfast and we didn't finish it. It's just that there is no boiling water in the pot."
Very Good
98 reviews
8.6/10
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Trip.com Hotel Insights for Lake City: Pricing, Trends & Booking Tips

Use Trip.com data-based seasonal trends and best booking times to plan and book your next hotel in Lake City.

Which month has the cheapest hotel rates in Lake City?

May is the most affordable month to book a hotel in Lake City, with average nightly rates around US$79. Prices peak in March, when rates reach about US$160 per night.
(Based on Trip.com data from June 8, 2025 to June 8, 2026.)
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May

What is the cheapest day of the week for hotels in Lake City?

Hotel rates in Lake City are typically lowest on Saturday, with average nightly rates around US$95. Wednesday tends to be the most expensive, averaging US$127 per night.
(Based on Trip.com data from June 8, 2025 to June 8, 2026.)
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Find unique stays in Lake City

Immerse yourself in the vibrant atmosphere of Lake City with our handpicked accommodation options

Top hotel picks in Lake City

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Check out these top-booked hotels from the past 30 days!
Baymont by Wyndham Lake City Hotels in Lake City
5.5/10
98 Reviews

Baymont by Wyndham Lake City

Hotel near Lake City
Top-Booked hotels in Lake City
Thank you for choosing our Baymont Inn and Suites in Lake City FL conveniently located off the highway in the heart of several well know natural springs. We specialize in hometown hospitality feature both traditional guest rooms and suites. Free guest amenities include a full continental breakfast at the Baymont Breakfast Corner wireless high-speed internet access use of the Baymont fitness center and fresh-baked chocolate chip cookies during the evening hours. When staying with us you will always have several options for dining - from Bob Evans located right next to us to Longhorn Steakhouse Olive Garden Cracker Barrell Texas Roadhouse Sunnys Barbeque which are all walking distance from us. For those looking to grab a quick meal on the go there are also several fast food options within 0.5 miles of us. We welcome pets for a nominal fee. Please review our pet policy or call us directly for more details.
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Hampton Inn & Suites Lake City Hotels in Lake City
9.3/10
105 Reviews

Hampton Inn & Suites Lake City

Hotel near Lake City
Top-Booked hotels in Lake City
The Hampton Inn and Suites is Lake City's premier limited service hotel. This beautiful, state of the art facility offers luxurious guest rooms, a fitness room, business center, suite shop, outdoor pool and spa, and so much more, all nestled in a gorgeous five story complex. The Hampton Inn and Suites combines superior accommodations for both the business traveler as well as the vacationing families with a touch of southern comfort and hospitality. Experience out guest room comfort and convenience. Every room is equipped with flat screen high definition television, microwave, refrigerator, electronic safe, coffee maker, iron and ironing board, full desk as well as portable lap desk. High speed wireless internet access is standard in our guest rooms and throughout the hotel. Enjoy sweet dreams in the new Hampton bed, Cloud Nine, which features a comfy mattress, soft new sheets, choice of feather or foam pillows and a plush, down-like blanket and duvet. Enjoy our complimentary On the House hot breakfast. Menu items vary and may include sausage, eggs and French toast sticks. Our cast selection of cereals, breakfast cakes, muffins, fresh fruit and juices will get your morning off to the right start. A new blend of robust coffee awaits you. In a hurry? Ask the breakfast hostess for your On the Run Breakfast Bag, complete with water fruit muffin, breakfast bar and a special treat.
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Fairfield Inn & Suites Lake City Hotels in Lake City
8.8/10
78 Reviews

Fairfield Inn & Suites Lake City

Hotel near Lake City
Top-Booked hotels in Lake City
Get comfortable at Fairfield Inn & Suites Lake City, a pet-friendly hotel in Lake City, FL, designed to help you recharge on the road. Relax in rooms and suites with plush Marriott bedding, ergonomic workspaces, and free Wi‑Fi. Start your day with complimentary breakfast, then explore nearby dining like Sonny's BBQ, Cedar River Seafood, and Red Lobster. Stay active with our indoor pool, hot tub, and 24‑hour fitness center. Enjoy easy access to Ichetucknee Springs State Park, Olustee Battlefield Historic State Park, and Spirit of the Suwannee Music Park. Our hotel near I‑75 also features an onsite venue ideal for meetings and events, with discounted group rates available. Whatever brings you to Lake City, enjoy a comfortable stay with us..
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TownePlace Suites By Marriott Lake City Hotels in Lake City
9.6/10
50 Reviews

TownePlace Suites By Marriott Lake City

Hotel near Lake City
Top-Booked hotels in Lake City
Experience Lake City's newest Marriott Hotel, located beside Lake City Medical Center, close to I-75 & I-10. Centrally located to Gainesville, Jacksonville, and Tallahassee. Feel the many charms of our historic downtown, numerous restaurants and even discover the many wonders of our gorgeous natural springs. TownePlace Suites by Marriott is an extended-stay hotel where you can balance work and life as you like, with the comfort, flexibility and affordability you require. Relax and feel at home with a fully equipped kitchen and high-speed Internet access. PET FRIENDLY!
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Home2 Suites by Hilton Lake City Hotels in Lake City
9.4/10
98 Reviews

Home2 Suites by Hilton Lake City

Hotel near Lake City
Top-Booked hotels in Lake City
Ideally located at the “Gateway to Florida”, the comfortable Home2 Suites by Hilton Lake City offers fantastic connectivity to major cities including Gainesville, Orlando, Jacksonville and Tallahassee via the nearby I-10 and I-75. Explore historic downtown Lake City, just four miles from our all-suite hotel in Lake City, FL. Enjoy easy access to lots of area attractions including shopping malls, historic sites and the Ichetucknee Springs State Park. Settle into a spacious studio or one-bedroom suite. The flexible “Working Wall” lets you customize your own space to fit your needs. Relax on the sleeper sofa and connect to your social network with free WiFi. Get to work at the moveable desk/table, or channel surf on the HDTV. Cook meals in your full kitchen, equipped with a dishwasher, microwave and refrigerator. Don’t forget the dog bowl and leash – your pet is more than welcome at this extended-stay Lake City hotel. Each morning of your stay, join us for free breakfast at our Inspired Table™. Pick up snacks, light meals and travel essentials 24/7 at Home2 MKT®. Enjoy fantastic amenities at this welcoming hotel in Lake City. Soak up the glorious Florida sunshine as you refresh in the outdoor swimming pool, or relax on the outdoor patio, which features a cozy fire pit and cooking grills. Do some laundry while you exercise in our integrated laundry/fitness facility, Spin2Cycle. Charge your smart phone, watch the HDTV, or check emails in the relaxed Oasis lobby lounge.
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Quality Inn Lake City Hotels in Lake City
8.0/10
100 Reviews

Quality Inn Lake City

Hotel near Lake City
Top-Booked hotels in Lake City
Located in Lake City, Quality Inn Lake City is within a 15-minute walk of Fresenius Medical Care at Lake City Medical Center and Lake City Medical Center. This hotel is 0.8 mi (1.2 km) from Regal UA Cinema 90 and 1 mi (1.6 km) from Lake City Mall. Be sure to enjoy recreational amenities including an outdoor pool and a fitness center. This hotel also features complimentary wireless internet access, a fireplace in the lobby, and a picnic area. A complimentary self-serve breakfast is served daily from 6 AM to 9:00 AM. Featured amenities include a business center, a 24-hour front desk, and an elevator. Free self parking is available onsite. Make yourself at home in one of the 55 guestrooms featuring refrigerators and LCD televisions. Your room comes with a pillowtop bed. Complimentary wireless internet access keeps you connected, and cable programming is available for your entertainment. Bathrooms feature shower/tub combinations with rainfall showerheads and hair dryers.
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Days Inn by Wyndham Lake City I-75 Hotels in Lake City
7.5/10
101 Reviews

Days Inn by Wyndham Lake City I-75

Hotel near Lake City
Top-Booked hotels in Lake City
Welcome to the Days Inn Lake City FL. Whether you are traveling for business or pleasure you will appreciate a hotel that offers useful amenities and superior customer service. This is exactly what you will find at our two diamond Days Inn hotel. We are conveniently located off I-75 exit 427 .25 miles from 1-75 the closest Days Inn to Lake City VA hospital and just four miles west of Historic Downtown Lake City. You will find plenty of activities for everyone in your family to enjoy whether you are exploring historic Olustee Battlefield Enjoying nature in the Osceola National Forest or picnicking at the Itchetucknee State Park or the Suwanee River. Enjoy free continental breakfast together with coffee tea and juice and stay connected with free Wifi.
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Days Inn by Wyndham Lake City I-10 Hotels in Lake City
7.0/10
101 Reviews

Days Inn by Wyndham Lake City I-10

Hotel near Lake City
Top-Booked hotels in Lake City
Our Days Inn Lake City I-10 hotel is conveniently located at the gateway to the Sunshine State. We offer easy access to historic sightseeing shopping and entertainment. Our clean and accommodating guest rooms were designed with your comfort in mind featuring thoughtful amenities to brighten your stay.
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Motel 6 Lake City, FL – Medical Center Hotels in Lake City
7.6/10
71 Reviews

Motel 6 Lake City, FL – Medical Center

Hotel near Lake City
Top-Booked hotels in Lake City
With a stay at Motel 6 – Lake City, Fl – Medical Center in Lake City, you'll be within a 10-minute walk of Fresenius Medical Care at Lake City Medical Center and Lake City Medical Center. This motel is 0.7 mi (1.1 km) from Regal UA Cinema 90 and 1 mi (1.5 km) from Lake City Mall. This motel offers designated smoking areas. Featured amenities include a 24-hour front desk and a vending machine. Free self parking is available onsite. Make yourself at home in one of the air-conditioned guestrooms. Complimentary wireless internet access is available to keep you connected. Bathrooms with bathtubs or showers are provided.
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Regal Inn Hotels in Lake City
8.4/10
100 Reviews

Regal Inn

Hotel near Lake City
Top-Booked hotels in Lake City
With a stay at Regal Inn in Lake City, you'll be a 5-minute walk from Regal UA Cinema 90 and 10 minutes by foot from Lake City Mall. This hotel is 0.6 mi (0.9 km) from Fresenius Medical Care at Lake City Medical Center and 0.6 mi (1 km) from Lake City Medical Center. This hotel offers designated smoking areas. Free self parking is available onsite. Make yourself at home in one of the 20 guestrooms. Complimentary wireless internet access is available to keep you connected. Bathrooms feature bathtubs or showers, hair dryers, and toothbrushes and toothpaste. Conveniences include a turndown service and irons/ironing boards, as well as phones with free local calls.
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FAQs about Lake City hotels

What hotels in Lake City offer an especially good breakfast?

Begin your day with a tasty and satisfying breakfast! Best Western Plus Lake City (price from US$91), Tru by Hilton Lake City (price from US$103) and Hampton Inn & Suites Lake City (price from US$112) provide the best breakfast to start your day.

Which hotels in Lake City provide fitness facilities?

Baymont by Wyndham Lake City (price from US$55), Best Western Plus Lake City (price from US$91) and La Quinta by Wyndham Lake City (price from US$76) include fitness facilities, so you can maintain your routine while traveling. Stay on track with your fitness goals while on the go!

What are the best hotels with a spa in Lake City?

A spa hotel can make your trip more enjoyable with relaxing amenities. Baymont by Wyndham Lake City (price from US$55) is one of the best hotels with a spa in the area.

Which hotels in Lake City have pools?

Baymont by Wyndham Lake City (price from US$55), La Quinta by Wyndham Lake City (price from US$76) and Americas Best Value Inn Lake City (price from US$63) are excellent options for hotels with swimming pools. Book your stay to enjoy the pool and make your trip more enjoyable.

How to get good deals on hotels in Lake City?

Find the best hotel deals and promotions on Trip.com, available year-round for both first-time and loyal users. Please check the promotions page to see what promotions are available now on Trip.com.

More Info about Hotels in Lake City

Number of Reviews
2,088
Total Properties
24
Weekday Avg. Price
US$122
Weekend Avg. Price
US$150
Trending hotel
Baymont by Wyndham Lake City