The hotel receptionist was incredibly wonderful. If I could meet her, I'd definitely stay here again. The Colosseum was so close, it was easy to see from the street. I recommend booking early in the morning, when there aren't many people. The Trevi Fountain is also very close! However, carrying heavy suitcases from Termini Station may be a bit difficult.
We stayed in the annex. It offered a glimpse into Italian life, and I was very satisfied. The bathroom was a little rough by Japanese standards, but it wasn't a problem. Since we stayed two nights, we didn't need cleaning, but some people came in through the window (which was open even though it was closed) to ventilate the room, so be careful if you're concerned about keeping your valuables and suitcases safe.
The annex (137 Via Serpenti) does not have an elevator, so be careful if you have heavy suitcases. The hotel staff will probably help you get there, but you'll need to carry your suitcases yourself when checking out. If you forget where the annex is, see this comment.
They also called a taxi for us on the way back. The ride to Termini Station, including tip, cost 16 euros for two heavy suitcases (around 10:30 on a weekday).
Breakfast was delicious, but I don't think it's necessary, as there's a cafe between the main building and the annex (a 2-minute walk). (Beware of staff trying to sell you cookies. They're highly rated and delicious!)
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