Cheapest airlines flights from Cusco to Santiago

You can pick from 3 carriers that fly from Cusco to Santiago including LATAM Airlines, avianca, JetSMART Airlines, with LATAM Airlines serving cheapest ticket on this route.

Search for direct flights from Cusco to Santiago in the next 3 months. Based on Trip.com's latest 7-day flight data, one-way direct flights start at HK$687, and round-trip direct flights start at HK$2,317.

Displayed flight fares from Cusco to Santiago are based on average prices across airlines for the next 3 months, according to the latest Trip.com database.

Cusco to Santiago Flight Details

The distance between Cusco and Santiago is about 2,211.1 km. The average flying time from Cusco to Santiago is around 2 hours 20 minutes. Based on Trip.com's latest data, travel demand is highest in July. The off-season for travel is December.

Cheapest one-way flight priceHK$598
Cheapest return ticket priceHK$1,728
Cheapest monthDecember
Peak season for travelJuly
Flight distance2,211.1 km
Average flight time2 hours 20 minutes
Popular airlineLATAM Airlines

When is the cheapest time to book flights from Cusco to Santiago?

The cheapest time to fly from Cusco to Santiago: Dec 21 to Dec 28 — one-way prices start at HK$597.

Cheapest flights
From price
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  • 714
  • 1421
  • 2128
  • Jan

    284
  • 411
  • 1118
  • 1825
  • Feb

    251
  • 18
  • 815
  • 1522
  • Mar

    221
Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Frequently Asked Questions

  • What are the cheapest flights from Cusco to Santiago (CUZ-SCL)?

    Based on Trip.com data, JetSMART Airlines offers one-way fares as low as HK$598 on Cheapest nonstop routes (e.g. CUZ to SCL on Fri, Dec 26), while JetSMART Airlines offers Cheapest nonstop round-trips from HK$1,728 departing on Sun, Dec 21 and returning on Tue, Dec 23.
  • At the moment, you can catch a nonstop flight from Cusco to Santiago with the following airlines, including: LATAM Airlines Selected airlines are based on historical data collected from flight bookings users made on Trip.com within the last 90 days.
  • It takes about 2 hours 20 minutes to fly from Cusco to Santiago.
  • By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Cusco to Santiago is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.
  • Based on Trip.com data in the past 4 weeks, there is 7 flight per week flying from Cusco to Santiago. You can check the weekly schedule for popular airlines on this route below: LATAM Airlines: S/M/T/W/T/F/S -- LA2366 (09:33)
  • To find best deals on flights from Cusco to Santiago, you can use various tools on Trip.com:
    · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Fri, Dec 26, with one-way flights priced at just HK$598.
    · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is LATAM Airlines.
    · Set up price alerts to easily monitor ticket prices without having to check every day.
    · Check Trip.com flight deals and promo codes frequently.
    · Avoid peak season unless you book very early. It seems the peak season for Santiago travel is around July.
    · Get exclusive promo codes for Trip.com app users.
  • The cheapest months to fly from Cusco to Santiago is December, when demand for travel is lower.
  • After crunching the numbers on our December flight calendar, it's currently cheapest to fly from Cusco to Santiago on December 12, 2025 with JetSMART, with prices starting at HK$560.
  • You can land at any one of the following hubs in Santiago, with Alejandro Velasco Astete International Airport to Arturo Merino Benitez International Airport (CUZ-SCL) is by far the most common option on this route: Arturo Merino Benitez International Airport (SCL).
  • The time difference between Santiago and Cusco is 1h.
  • Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.