Cheapest airlines flights from Cusco to Santiago
LATAM Airlines
JetSMART Airlines Find Cheapest Flights from Cusco to Santiago
Search for direct flights from Cusco to Santiago in the next 3 months. Based on Trip.com's latest 7-day flight data, one-way direct flights start at US$145, and round-trip direct flights start at US$311.
- Round-trip
- One way
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- Cheapest nonstop
CUZ 09:303h 20mNonstopSCL 13:50Cusco - Santiago | Wed, Apr 22 | LATAM Airlines
SCL 19:453h 30mNonstopCUZ 22:15Santiago - Cusco | Sat, Apr 25 | LATAM AirlinesUS$311 US$42326% off26% offUS$423 US$311 -
CUZ 18:458h 26m1 stopSCL 04:11Cusco - Santiago | Fri, Apr 24 | JetSMART Airlines
SCL 04:5611h 29m1 stopCUZ 15:25Santiago - Cusco | Sun, Apr 26 | JetSMART AirlinesUS$224 US$42347% off47% offUS$423 US$224 -
CUZ 16:3010h 26m1 stopSCL 03:56Cusco - Santiago | Wed, Apr 22 | JetSMART Airlines
SCL 19:453h 30mNonstopCUZ 22:15Santiago - Cusco | Sat, Apr 25 | LATAM AirlinesUS$241 US$42343% off43% offUS$423 US$241 -
CUZ 21:4014h 50m1 stopSCL 13:30Cusco - Santiago | Wed, Apr 22 | Sky Airline
SCL 19:453h 30mNonstopCUZ 22:15Santiago - Cusco | Sat, Apr 25 | LATAM AirlinesUS$26537% offUS$423 US$265 -
CUZ 21:4014h 50m1 stopSCL 13:30Cusco - Santiago | Fri, Apr 24 | Sky Airline
SCL 04:5611h 29m1 stopCUZ 15:25Santiago - Cusco | Sun, Apr 26 | JetSMART AirlinesUS$27834% offUS$423 US$278 -
CUZ 09:303h 20mNonstopSCL 13:50Cusco - Santiago | Fri, Apr 24 | LATAM Airlines
SCL 04:5611h 29m1 stopCUZ 15:25Santiago - Cusco | Sun, Apr 26 | JetSMART AirlinesUS$29430% offUS$423 US$294 -
CUZ 21:4014h 50m1 stopSCL 13:30Cusco - Santiago | Tue, May 26 | Sky Airline
SCL 11:3510h 25m1 stopCUZ 21:00Santiago - Cusco | Sat, May 30 | Sky AirlineUS$30028% offUS$423 US$300 -
CUZ 21:4014h 50m1 stopSCL 13:30Cusco - Santiago | Thu, May 21 | Sky Airline
SCL 11:3510h 25m1 stopCUZ 21:00Santiago - Cusco | Sat, May 23 | Sky AirlineUS$30028% offUS$423 US$300 -
CUZ 14:403h 20mNonstopSCL 19:00Cusco - Santiago | Thu, May 21 | LATAM Airlines
SCL 11:3510h 25m1 stopCUZ 21:00Santiago - Cusco | Sat, May 23 | Sky AirlineUS$31526% offUS$423 US$315 -
CUZ 17:0010h 16m1 stopSCL 04:16Cusco - Santiago | Thu, May 21 | JetSMART Airlines
SCL 11:3510h 25m1 stopCUZ 21:00Santiago - Cusco | Sat, May 23 | Sky AirlineUS$32124% offUS$423 US$321 -
CUZ 13:0017h 25m1 stopSCL Invalid DateCusco - Santiago | Thu, Apr 23 | Normal Airline
SCL 15:006hNonstopCUZ 16:00Santiago - Cusco | Sat, Apr 25 | Normal AirlineFind more flightsFind more flights
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Cheapest nonstop
CUZ 09:303h 20mNonstopSCL 13:50Cusco - Santiago | Sun, May 17 | LATAM AirlinesUS$145 US$19124% off24% offUS$191 US$145 -
CUZ 09:303h 20mNonstopSCL 13:50Cusco - Santiago | Sat, May 16 | LATAM AirlinesUS$145 US$19124% off24% offUS$191 US$145 -
CUZ 19:457h 26m1 stopSCL 04:11Cusco - Santiago | Mon, Apr 27 | JetSMART AirlinesUS$103 US$19146% off46% offUS$191 US$103 -
CUZ 16:3510h 21m1 stopSCL 03:56Cusco - Santiago | Thu, Jun 11 | JetSMART AirlinesUS$10346% offUS$191 US$103 -
CUZ 18:458h 26m1 stopSCL 04:11Cusco - Santiago | Sat, Jun 6 | JetSMART AirlinesUS$10446% offUS$191 US$104 -
CUZ 17:159h 56m1 stopSCL 04:11Cusco - Santiago | Sun, Jun 14 | JetSMART AirlinesUS$10943% offUS$191 US$109 -
CUZ 13:2013h 51m1 stopSCL 04:11Cusco - Santiago | Sat, May 16 | JetSMART AirlinesUS$11142% offUS$191 US$111 -
CUZ 17:159h 56m1 stopSCL 04:11Cusco - Santiago | Sun, May 10 | JetSMART AirlinesUS$11142% offUS$191 US$111 -
CUZ 16:1011h 1m1 stopSCL 04:11Cusco - Santiago | Sat, May 23 | JetSMART AirlinesUS$11241% offUS$191 US$112 -
CUZ 16:5010h 26m1 stopSCL 04:16Cusco - Santiago | Tue, May 12 | JetSMART AirlinesUS$11639% offUS$191 US$116 -
CUZ 16:2710h 34m1 stopSCL 04:01Cusco - Santiago | Fri, Apr 24 | JetSMART AirlinesUS$11838% offUS$191 US$118 -
CUZ 15:4711h 14m1 stopSCL 04:01Cusco - Santiago | Thu, Jun 4 | JetSMART AirlinesUS$12037% offUS$191 US$120 -
CUZ 13:0017h 25m1 stopSCL Invalid DateCusco - Santiago | Thu, Apr 23 | Normal AirlineFind more flightsFind more flights
Displayed flight fares from Cusco to Santiago are based on average prices across airlines for the next 3 months, according to the latest Trip.com database.
Cusco to Santiago Flight Details
The distance between Cusco and Santiago is about 2,211.1 km. The average flying time from Cusco to Santiago is around 2 hours 50 minutes. Based on Trip.com's latest data, travel demand is highest in July. The off-season for travel is December.
| Cheapest one-way flight price | US$103 |
|---|---|
| Cheapest return ticket price | US$224 |
| Cheapest month | December |
| Peak season for travel | July |
| Flight distance | 2,211.1 km |
| Average flight time | 2 hours 50 minutes |
| Popular airline | LATAM Airlines |
Trip.com Price Insights on Flights from Cusco to Santiago
Which month has the cheapest one-way flights from Cusco to Santiago?
Based on Trip.com’s data, the cheapest month for flights from Cusco to Santiago is April, with an average price of US$172; while the month with the highest flight price is usually February, with an average price of up to US$456.
What is the cheapest day of the week to fly from Cusco to Santiago?
Based on Trip.com’s past 12 months of flight data, the cheapest day to fly from Cusco to Santiago is Wednesday, with average prices lower than on other days. Avoid Saturday, as prices are usually highest then.
When is the cheapest day to fly from Cusco to Santiago during International Workers' Day?
International Workers' Day is scheduled for May 1. The cheapest flights from Cusco to Santiago are available on Apr 29, with fares starting at US$127.
Frequently Asked Questions
What are the cheapest flights from Cusco to Santiago (CUZ-SCL)?
Based on Trip.com data, JetSMART Airlines offers one-way fares as low as US$103 on Cheapest nonstop routes (e.g. CUZ to SCL on Mon, Apr 27), while JetSMART Airlines offers Cheapest nonstop round-trips from US$224 departing on Fri, Apr 24 and returning on Sun, Apr 26.Which airlines offer direct flights from Cusco to Santiago?
At the moment, you can catch a nonstop flight from Cusco to Santiago with the following airlines, including: LATAM Airlines Selected airlines are based on historical data collected from flight bookings users made on Trip.com within the last 90 days.How long is a flight from Cusco to Santiago?
It takes about 2 hours 50 minutes to fly from Cusco to Santiago.When is the best time to book flights from Cusco to Santiago?
By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Cusco to Santiago is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.How many flights are there per week from Cusco to Santiago?
Based on Trip.com data in the past 4 weeks, there is 9 flight per week flying from Cusco to Santiago. You can check the weekly schedule for popular airlines on this route below: LATAM Airlines: -/-/T/-/T/-/S -- LA2466 (14:51) LATAM Airlines: S/M/T/W/T/F/S -- LA2366 (09:37)How can I find the best deals on flights from Cusco to Santiago?
To find best deals on flights from Cusco to Santiago, you can use various tools on Trip.com:
· Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Mon, Apr 27, with one-way flights priced at just US$103.
· Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is LATAM Airlines.
· Set up price alerts to easily monitor ticket prices without having to check every day.
· Check Trip.com flight deals and promo codes frequently.
· Avoid peak season unless you book very early. It seems the peak season for Santiago travel is around July.
· Get exclusive promo codes for Trip.com app users.When are flight tickets from Cusco (CUZ) to Santiago (SCL) the cheapest?
The cheapest months to fly from Cusco to Santiago is December, when demand for travel is lower.Which upcoming date is cheapest to fly from Cusco to Santiago on?
After crunching the numbers on our April flight calendar, it's currently cheapest to fly from Cusco to Santiago on April 23, 2026 with JetSMART, with prices starting at US$97.Which airports can I fly to for Santiago from Cusco?
You can land at any one of the following hubs in Santiago, with Alejandro Velasco Astete International Airport to Arturo Merino Benitez International Airport (CUZ-SCL) is by far the most common option on this route: Arturo Merino Benitez International Airport (SCL).Is there any time difference between Cusco and Santiago?
The time difference between Santiago and Cusco is 1h.How do I change or cancel my ticket from Cusco to Santiago?
Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.
Trip.com Airline Insights on Flights from Cusco to Santiago
Which airline offers the cheapest direct flights from Cusco to Santiago?
Based on Trip.com’s data from the past 12 months, JetSMART Airlines provides the lowest-priced direct flights from Cusco to Santiago, with fares starting at US$161.
How many flights fly from Cusco to Santiago daily?
Based on the past month's historical data from Trip.com, the number of flights from Cusco to Santiago is the highest on Sunday and the lowest on Monday/Tuesday/Thursday.
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Note: Prices shown on this page are the estimated lowest prices found in the last 24 hours and include all taxes and fees.