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Flights from Midland to San Diego

Search cheap flights from Midland to San Diego in the next 3 months. Based on Trip.com's latest 7-day data, one-way fares start at US$205, and round-trip tickets start at US$370.

      • MAF 09:20
        4h 28m
        1 stop
        SAN 11:48
        Midland - San Diego | Tue, Jul 14 | American Airlines
        SAN 15:08
        5h 45m
        1 stop
        MAF 22:53
        San Diego - Midland | Tue, Jul 21 | American Airlines
        US$370 US$720
        49% off
        49% off
        US$720 US$370
      • MAF 20:23
        5h 36m
        1 stop
        SAN 23:59
        Midland - San Diego | Fri, May 29 | American Airlines
        SAN 15:10
        6h 34m
        1 stop
        MAF 23:44
        San Diego - Midland | Tue, Jun 2 | United Airlines
        US$388 US$720
        46% off
        46% off
        US$720 US$388
      • MAF 20:23
        5h 36m
        1 stop
        SAN 23:59
        Midland - San Diego | Wed, May 27 | American Airlines
        SAN 15:10
        6h 6m
        1 stop
        MAF 23:16
        San Diego - Midland | Wed, Jun 3 | American Airlines
        US$396 US$720
        45% off
        45% off
        US$720 US$396
      • MAF 18:49
        7h 10m
        1 stop
        SAN 23:59
        Midland - San Diego | Tue, Jun 16 | American Airlines
        SAN 15:10
        6h 34m
        1 stop
        MAF 23:44
        San Diego - Midland | Tue, Jun 23 | United Airlines
        US$398
        45% off
        US$720 US$398
      • MAF 09:37
        5h 44m
        1 stop
        SAN 13:21
        Midland - San Diego | Tue, Jul 14 | United Airlines
        SAN 15:08
        5h 45m
        1 stop
        MAF 22:53
        San Diego - Midland | Tue, Jul 21 | American Airlines
        US$400
        44% off
        US$720 US$400
      • MAF 05:00
        5h 22m
        1 stop
        SAN 08:22
        Midland - San Diego | Sat, Jun 6 | American Airlines
        SAN 15:10
        6h 49m
        1 stop
        MAF 23:59
        San Diego - Midland | Fri, Jun 12 | American Airlines
        US$402
        44% off
        US$720 US$402
      • MAF 07:00
        8h 21m
        1 stop
        SAN 13:21
        Midland - San Diego | Fri, May 29 | United Airlines
        SAN 15:10
        6h 34m
        1 stop
        MAF 23:44
        San Diego - Midland | Tue, Jun 2 | United Airlines
        US$409
        43% off
        US$720 US$409
      • MAF 13:00
        17h 25m
        1 stop
        SAN 14:00
        Midland - San Diego | Sun, May 24 | Normal Airline
        SAN 15:00
        6h
        Nonstop
        MAF 16:00
        San Diego - Midland | Tue, May 26 | Normal Airline
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      • MAF 17:18
        7h 7m
        1 stop
        SAN 22:25
        Midland - San Diego | Fri, Jun 5 | United Airlines
        US$205 US$247
        17% off
        17% off
        US$247 US$205
      • MAF 11:35
        7h 45m
        1 stop
        SAN 17:20
        Midland - San Diego | Thu, Jun 4 | United Airlines
        US$209 US$247
        15% off
        15% off
        US$247 US$209
      • MAF 20:23
        5h 36m
        1 stop
        SAN 23:59
        Midland - San Diego | Thu, Jun 4 | American Airlines
        US$211 US$247
        15% off
        15% off
        US$247 US$211
      • MAF 20:23
        5h 36m
        1 stop
        SAN 23:59
        Midland - San Diego | Fri, Jun 5 | American Airlines
        US$211
        15% off
        US$247 US$211
      • MAF 07:00
        8h 21m
        1 stop
        SAN 13:21
        Midland - San Diego | Thu, Jun 18 | United Airlines
        US$212
        14% off
        US$247 US$212
      • MAF 11:35
        7h 45m
        1 stop
        SAN 17:20
        Midland - San Diego | Thu, Jun 11 | United Airlines
        US$212
        14% off
        US$247 US$212
      • MAF 05:00
        5h 22m
        1 stop
        SAN 08:22
        Midland - San Diego | Mon, Jun 8 | American Airlines
        US$216
        13% off
        US$247 US$216
      • MAF 17:13
        6h 11m
        1 stop
        SAN 21:24
        Midland - San Diego | Mon, Jun 8 | United Airlines
        US$219
        11% off
        US$247 US$219
      • MAF 13:00
        17h 25m
        1 stop
        SAN 14:00
        Midland - San Diego | Sun, May 24 | Normal Airline
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Displayed flight fares from Midland to San Diego are based on average prices across airlines for the next 3 months, according to the latest Trip.com database.

Frequently Asked Questions

  • What are the cheapest flights from Midland to San Diego (MAF-SAN)?

    Based on Trip.com data, United Airlines offers one-way fares as low as US$205 on Cheapest nonstop routes (e.g. MAF to SAN on Fri, Jun 5), while American Airlines offers Cheapest nonstop round-trips from US$370 departing on Tue, Jul 14 and returning on Tue, Jul 21.
  • It takes about 4 hours 20 minutes to fly from Midland to San Diego.
  • By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Midland to San Diego is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.
  • To find best deals on flights from Midland to San Diego, you can use various tools on Trip.com:
    · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Fri, Jun 5, with one-way flights priced at just US$205.
    · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is United Airlines.
    · Set up price alerts to easily monitor ticket prices without having to check every day.
    · Check Trip.com flight deals and promo codes frequently.
    · Avoid peak season unless you book very early. It seems the peak season for San Diego travel is around December.
    · Get exclusive promo codes for Trip.com app users.
  • The cheapest months to fly from Midland to San Diego is October, when demand for travel is lower.
  • After crunching the numbers on our May flight calendar, it's currently cheapest to fly from Midland to San Diego on May 29, 2026 with American Airlines, with prices starting at US$388.
  • The time difference between San Diego and Midland is 2h.
  • Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.

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Note: Prices shown on this page are the estimated lowest prices found in the last 24 hours and include all taxes and fees.

Book with no extra fees

Prices displayed on this page are all-inclusive (incl. taxes, fuel surcharges, Civil Aviation Development Fund, etc.), and all fees are clearly shown before you pay. Charges for checked baggage, onboard meals, Wi‑Fi, and other optional services are also included where applicable in the flight cards.

Real-time pricing updates

Prices, availability, and travel details on this page have been updated within the last 24 hours, and for many routes are refreshed in real time. The more popular the route, the more accurate and up-to-date the data.

Change & Cancellation Policy

Trip.com shows the change and cancellation rules for each ticket during the booking process, including all related fees and conditions. Please refer to the following scenarios:
Voluntary cancellation/change:
To request a change or cancellation, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and flight segment, and submit your request. Please note that additional charges may apply based on the airline’s fare rules.
Cancellation/change due to a flight schedule change:
If your flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For full details of change and cancellation policies, please refer to the customer support pages.