US$110️ Cheap Flights from Santiago to Santa Cruz (2024)

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Santiago to Santa Cruz - Flights Starting at US$110

Book one-way or return flights from Santiago to Santa Cruz from as little as US$110. Choose from the popular airlines below and book your flight today!

One way
Round-trip

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

We've found these cheap flights for you. You may book a one-way or round trip as per your needs.

We monitor flight fares to help you seize the best deals effortlessly

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Cheapest airlines flights from Santiago to Santa Cruz

View airlines operating flights from Santiago to Santa Cruz. Compare prices, find the option that best suits your travel needs, and enjoy a comfortable journey with a trusted airline.

LATAM Airlines

From US$110

Aerolineas Argentinas

From US$138

JetSMART Airlines

From US$161

Sky Airline

From US$192

JetSmart Airlines

From US$229

Avianca

From US$230

KLM

From US$368

Copa Airlines

From US$406

ANA airlines

Find more flights and airlines

Alternative Routes from Santiago to Santa Cruz

Discover different routes, airlines, and transfers and find the best alternative flights for your journey from Santiago to Santa Cruz.

Cheapest
SCL
19:55
8h 45m
1 transfer
VVI
04:40
Arturo Merino Benitez Airport - Viru Viru International Airport
Thu, Jun 6LATAM Airlines
US$110
SCL
19:55
8h 45m
1 transfer
VVI
04:40
Arturo Merino Benitez Airport - Viru Viru International Airport
Thu, Jun 6LATAM Airlines
US$110
Find More Flights

Frequently Asked Questions

When are flight tickets from Santiago (SCL) to Santa Cruz (SRZ) the cheapest?
Airlines adjust prices for flights from Santiago to Santa Cruz based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.
How much do flights from Santiago (SCL) to Santa Cruz (SRZ) cost?
According to Trip.com's data, the lowest price is around $364.
How long does it take to fly from Santiago (SCL) to Santa Cruz (SRZ) and what is the distance?
It takes around 4 hours 2 minutes to fly from Santiago (SCL) to Santa Cruz (SRZ).
What is the transportation method from the main airport to downtown in Santa Cruz?
- The distance from Viru Viru International Airport to downtown is about 17km. It takes about 30 minutes by taxi.
What are the most popular airlines that fly from Santiago (SCL) to Santa Cruz (SRZ)?
Airlines with flights from Santiago (SCL) to Santa Cruz (SRZ): LATAM Airlines.

How to find a cheap flight from Santiago to Santa Cruz

Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Santiago to Santa Cruz. Book your flights at the right time and save more.

Book Early

Once prices are gone, they're gone. Lock in deals while you can!

Compare Flight Prices

Compare prices on travel agency and airline websites.

Look Out for Deals

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Check One-way Fares

Buying two cheap one-way flights can sometimes be a better deal than a round-trip.

Try Different Dates

Flying during the week, early in the morning, or late at night can help save money.

Use the Trip.com App

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Santiago to Santa Cruz Flight Information

Cheapest nonstop flight price	$109
Cheapest round-trip ticket price	$249
Off-season for travel	June
Peak season for travel	October
Flight distance	1,893.1km
Average flight time	4 hours 2 minutes
Popular airline	Avianca