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Santo Domingo to San Francisco - Flights Starting at US$201

Book one-way or return flights from Santo Domingo to San Francisco from as little as US$201. Choose from the popular airlines below and book your flight today!

  • One way
  • Round-trip

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

We've found these cheap flights for you. You may book a one-way or round trip as per your needs.

We monitor flight fares to help you seize the best deals effortlessly

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.
Cheapest airlines flights from Santo Domingo to San Francisco

View airlines operating flights from Santo Domingo to San Francisco. Compare prices, find the option that best suits your travel needs, and enjoy a comfortable journey with a trusted airline.

Frontier Airlines
From US$192
Spirit Airlines
From US$198
American Airlines
From US$201
Copa Airlines
From US$224
Jetblue Airways
From US$227
Avianca
From US$250
Delta Air Lines
From US$267
DM Airlines
From US$283
United Airlines
From US$303
Aeromexico
From US$310
ANA airlines

Find more flights and airlines

Alternative Routes from Santo Domingo to San Francisco

Discover different routes, airlines, and transfers and find the best alternative flights for your journey from Santo Domingo to San Francisco.

  • Cheapest
    Frontier Airlines
    SDQ
    12:39
    35h 2m
    2 transfer
    SFO
    20:41
    Las Américas International Airport - San Francisco International Airport
    Tue, May 7Frontier Airlines
    US$192
  • Frontier Airlines
    SDQ
    12:39
    35h 2m
    2 transfer
    SFO
    20:41
    Las Américas International Airport - San Francisco International Airport
    Tue, May 7Frontier Airlines
    US$192
    Find More Flights

Frequently Asked Questions

  • When are flight tickets from Santo Domingo (SDQ) to San Francisco (SFO) the cheapest?

    Airlines adjust prices for flights from Santo Domingo to San Francisco based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.
  • How much do flights from Santo Domingo (SDQ) to San Francisco (SFO) cost?

    According to Trip.com's data, the lowest price is around $653.
  • What is the transportation method from the main airport to downtown in San Francisco?

    • The distance from San Francisco International Airport to downtown is about 17km. It takes about 30 minutes by taxi.

How to find a cheap flight from Santo Domingo to San Francisco

Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Santo Domingo to San Francisco. Book your flights at the right time and save more.
1
Book Early
Once prices are gone, they're gone. Lock in deals while you can!
2
Compare Flight Prices
Compare prices on travel agency and airline websites.
3
Look Out for Deals
Check airline and travel agency websites for latest flight deals
4
Check One-way Fares
Buying two cheap one-way flights can sometimes be a better deal than a round-trip.
5
Try Different Dates
Flying during the week, early in the morning, or late at night can help save money.
6
Use the Trip.com App
Save up to £10 per person when booking your flights on Trip.com
Santo Domingo to San Francisco Flight Information

Cheapest nonstop flight price

$201

Off-season for travel

February

Peak season for travel

July

Flight distance

5,492.83km

Popular airline

Aeromexico