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Chicago to Santa Ana - Flights Starting at US$61

Book one-way or return flights from Chicago to Santa Ana from as little as US$61. Choose from the popular airlines below and book your flight today!

  • One way
  • Round-trip

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

We've found these cheap flights for you. You may book a one-way or round trip as per your needs.

We monitor flight fares to help you seize the best deals effortlessly

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.
Cheapest airlines flights from Chicago to Santa Ana

View airlines operating flights from Chicago to Santa Ana. Compare prices, find the option that best suits your travel needs, and enjoy a comfortable journey with a trusted airline.

Spirit Airlines
From US$45
Frontier Airlines
From US$90
Alaska Airlines
From US$118
Delta Air Lines
From US$125
United Airlines
From US$132
Southwest Airlines
From US$180
American Airlines
From US$190
Allegiant Air
From US$211
Sun Country Airlines
From US$286
ANA airlines

Find more flights and airlines

Alternative Routes from Chicago to Santa Ana

Discover different routes, airlines, and transfers and find the best alternative flights for your journey from Chicago to Santa Ana.

  • Cheapest
    Spirit Airlines
    ORD
    07:03
    9h 44m
    2 transfer
    SNA
    14:47
    O'Hare International Airport - John Wayne Airport
    Tue, May 7Spirit Airlines
    US$45
  • Frontier Airlines
    MDW
    10:30
    11h 7m
    1 transfer
    SNA
    19:37
    Midway International Airport - John Wayne Airport
    Sat, May 4Frontier Airlines
    US$90
  • Allegiant Air
    RFD
    13:35
    10h 19m
    1 transfer
    SNA
    21:54
    Chicago Rockford International Airport - John Wayne Airport
    Fri, May 31Allegiant Air
    US$268
  • Allegiant Air
    RFD
    13:35
    10h 19m
    1 transfer
    SNA
    21:54
    Chicago Rockford International Airport - John Wayne Airport
    Fri, May 31Allegiant Air
    US$268
    Find More Flights

Frequently Asked Questions

  • When are flight tickets from Chicago (CHI) to Santa Ana (SNA) the cheapest?

    Airlines adjust prices for flights from Chicago to Santa Ana based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.
  • How much do flights from Chicago (CHI) to Santa Ana (SNA) cost?

    According to Trip.com's data, the lowest price is around $358.
  • How long does it take to fly from Chicago (CHI) to Santa Ana (SNA) and what is the distance?

    It takes around 4 hours 58 minutes to fly from Chicago (CHI) to Santa Ana (SNA).
  • What is the transportation method from the main airport to downtown in Santa Ana?

    • The distance from John Wayne Airport to downtown is about 7km. It takes about 20 minutes by taxi.
  • What are the most popular airlines that fly from Chicago (CHI) to Santa Ana (SNA)?

How to find a cheap flight from Chicago to Santa Ana

Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Chicago to Santa Ana. Book your flights at the right time and save more.
1
Book Early
Once prices are gone, they're gone. Lock in deals while you can!
2
Compare Flight Prices
Compare prices on travel agency and airline websites.
3
Look Out for Deals
Check airline and travel agency websites for latest flight deals
4
Check One-way Fares
Buying two cheap one-way flights can sometimes be a better deal than a round-trip.
5
Try Different Dates
Flying during the week, early in the morning, or late at night can help save money.
6
Use the Trip.com App
Save up to £10 per person when booking your flights on Trip.com
Chicago to Santa Ana Flight Information

Cheapest nonstop flight price

$61

Cheapest round-trip ticket price

$196

Off-season for travel

January

Peak season for travel

October

Flight distance

2,791.75km

Average flight time

4 hours 58 minutes

Popular airline

American Airlines