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Flights from Cleveland to Greenville

Search cheap flights from Cleveland to Greenville in the next 3 months. Based on Trip.com's latest 7-day data, one-way fares start at US$108, and round-trip tickets start at US$214.

      • CLE 05:26
        3h 52m
        1 stop
        GSP 09:18
        Cleveland - Greenville | Fri, Aug 7 | Delta Air Lines
        GSP 05:46
        3h 24m
        1 stop
        CLE 09:10
        Greenville - Cleveland | Tue, Aug 11 | Delta Air Lines
        US$214 US$429
        50% off
        50% off
        US$429 US$214
      • CLE 05:26
        3h 52m
        1 stop
        GSP 09:18
        Cleveland - Greenville | Thu, Aug 6 | Delta Air Lines
        GSP 05:46
        5h 43m
        1 stop
        CLE 11:29
        Greenville - Cleveland | Fri, Aug 14 | Delta Air Lines
        US$214 US$429
        50% off
        50% off
        US$429 US$214
      • CLE 07:49
        8h 21m
        1 stop
        GSP 16:10
        Cleveland - Greenville | Sun, Aug 9 | American Airlines
        GSP 06:27
        12h 57m
        1 stop
        CLE 19:24
        Greenville - Cleveland | Sun, Aug 16 | American Airlines
        US$245 US$429
        43% off
        43% off
        US$429 US$245
      • CLE 05:35
        6h 39m
        1 stop
        GSP 12:14
        Cleveland - Greenville | Thu, Jul 23 | Delta Air Lines
        GSP 08:52
        6h 28m
        1 stop
        CLE 15:20
        Greenville - Cleveland | Wed, Jul 29 | Delta Air Lines
        US$270
        37% off
        US$429 US$270
      • CLE 10:53
        6h 7m
        1 stop
        GSP 17:00
        Cleveland - Greenville | Sun, Aug 9 | United Airlines
        GSP 19:40
        4h 4m
        1 stop
        CLE 23:44
        Greenville - Cleveland | Tue, Aug 11 | United Airlines
        US$283
        34% off
        US$429 US$283
      • CLE 05:26
        3h 52m
        1 stop
        GSP 09:18
        Cleveland - Greenville | Tue, Sep 1 | Delta Air Lines
        GSP 05:46
        5h 43m
        1 stop
        CLE 11:29
        Greenville - Cleveland | Sat, Sep 5 | Delta Air Lines
        US$284
        34% off
        US$429 US$284
      • CLE 14:40
        5h 35m
        1 stop
        GSP 20:15
        Cleveland - Greenville | Thu, Jul 30 | Delta Air Lines
        GSP 08:49
        6h 36m
        1 stop
        CLE 15:25
        Greenville - Cleveland | Tue, Aug 4 | Delta Air Lines
        US$296
        31% off
        US$429 US$296
      • CLE 20:03
        3h 51m
        1 stop
        GSP 23:54
        Cleveland - Greenville | Mon, Jul 27 | Delta Air Lines
        GSP 17:16
        5h 14m
        1 stop
        CLE 22:30
        Greenville - Cleveland | Sun, Aug 2 | Delta Air Lines
        US$299
        30% off
        US$429 US$299
      • CLE 08:05
        5h 56m
        1 stop
        GSP 14:01
        Cleveland - Greenville | Sun, Jul 19 | Delta Air Lines
        GSP 05:44
        3h 26m
        1 stop
        CLE 09:10
        Greenville - Cleveland | Wed, Jul 22 | Delta Air Lines
        US$304
        28% off
        US$429 US$304
      • CLE 05:26
        3h 52m
        1 stop
        GSP 09:18
        Cleveland - Greenville | Tue, Aug 4 | Delta Air Lines
        GSP 06:55
        6h 47m
        1 stop
        CLE 13:42
        Greenville - Cleveland | Tue, Aug 11 | Delta Air Lines
        US$304
        28% off
        US$429 US$304
      • CLE 13:00
        17h 25m
        1 stop
        GSP 14:00
        Cleveland - Greenville | Tue, Jul 14 | Normal Airline
        GSP 15:00
        6h
        Nonstop
        CLE 16:00
        Greenville - Cleveland | Thu, Jul 16 | Normal Airline
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      • CLE 18:18
        4h 41m
        1 stop
        GSP 22:59
        Cleveland - Greenville | Mon, Aug 10 | Delta Air Lines
        US$108 US$223
        52% off
        52% off
        US$223 US$108
      • CLE 05:35
        6h 39m
        1 stop
        GSP 12:14
        Cleveland - Greenville | Wed, Jul 29 | Delta Air Lines
        US$132 US$223
        41% off
        41% off
        US$223 US$132
      • CLE 08:05
        5h 56m
        1 stop
        GSP 14:01
        Cleveland - Greenville | Sat, Aug 1 | Delta Air Lines
        US$132 US$223
        41% off
        41% off
        US$223 US$132
      • CLE 10:15
        3h 46m
        1 stop
        GSP 14:01
        Cleveland - Greenville | Tue, Jul 28 | Delta Air Lines
        US$139
        38% off
        US$223 US$139
      • CLE 12:35
        3h 40m
        1 stop
        GSP 16:15
        Cleveland - Greenville | Thu, Aug 27 | Delta Air Lines
        US$146
        35% off
        US$223 US$146
      • CLE 08:09
        5h 46m
        1 stop
        GSP 13:55
        Cleveland - Greenville | Fri, Aug 7 | Delta Air Lines
        US$146
        35% off
        US$223 US$146
      • CLE 07:05
        5h 36m
        1 stop
        GSP 12:41
        Cleveland - Greenville | Fri, Aug 21 | Delta Air Lines
        US$157
        30% off
        US$223 US$157
      • CLE 05:00
        5h 12m
        1 stop
        GSP 10:12
        Cleveland - Greenville | Tue, Jul 14 | American Airlines
        US$158
        28% off
        US$223 US$158
      • CLE 05:22
        7h 4m
        1 stop
        GSP 12:26
        Cleveland - Greenville | Wed, Jul 15 | American Airlines
        US$158
        28% off
        US$223 US$158
      • CLE 13:00
        17h 25m
        1 stop
        GSP 14:00
        Cleveland - Greenville | Tue, Jul 14 | Normal Airline
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Displayed flight fares from Cleveland to Greenville are based on average prices across airlines for the next 3 months, according to the latest Trip.com database.

Cheapest airlines flights from Cleveland to Greenville

You can choose from 1 airlines that fly from Cleveland to Greenville, including Delta Air Lines, Delta Air Lines has lowest fares on this route.
Delta Air Lines logo Delta Air Lines
Airlines are determined based on actual purchased flight tickets from Cleveland to Greenville according to previous 12 months data from Trip.com.

Cleveland to Greenville Flight Details

The distance between Cleveland and Greenville is about 731.66 km. Based on Trip.com's latest data, travel demand is highest in July. The off-season for travel is August.

Cheapest one-way flight priceUS$108
Cheapest return ticket priceUS$214
Cheapest monthAugust
Peak season for travelJuly
Flight distance731.66 km
Popular airlineDelta Air Lines
Flight statistics for the Cleveland–Greenville route are based on aggregated booking data from Trip.com over the past 12 months.

Frequently Asked Questions

  • What are the cheapest flights from Cleveland to Greenville (CLE-GSP)?

    Based on Trip.com data, Delta Air Lines offers one-way fares as low as US$108 on Cheapest nonstop routes (e.g. CLE to GSP on Mon, Aug 10), while Delta Air Lines offers Cheapest nonstop round-trips from US$214 departing on Fri, Aug 7 and returning on Tue, Aug 11.
  • At the moment, several airlines serve connecting flights from Cleveland to Greenville, including: Delta Air Lines Selected airlines are based on historical data collected from flight bookings made by users on Trip.com within the last 90 days.
  • By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Cleveland to Greenville is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.
  • To find best deals on flights from Cleveland to Greenville, you can use various tools on Trip.com:
    · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Mon, Aug 10, with one-way flights priced at just US$108.
    · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is Delta Air Lines.
    · Set up price alerts to easily monitor ticket prices without having to check every day.
    · Check Trip.com flight deals and promo codes frequently.
    · Avoid peak season unless you book very early. It seems the peak season for Greenville travel is around July.
    · Get exclusive promo codes for Trip.com app users.
  • The cheapest months to fly from Cleveland to Greenville is August, when demand for travel is lower.
  • After crunching the numbers on our July flight calendar, it's currently cheapest to fly from Cleveland to Greenville on July 22, 2026 with Delta Air Lines, with prices starting at US$270.
  • You can land at any one of the following hubs in Greenville, with Cleveland Hopkins International Airport to Greenville-Spartanburg International Airport (CLE-GSP) is by far the most common option on this route: Greenville-Spartanburg International Airport (GSP).
  • The time difference between Greenville and Cleveland is 0h.
  • Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.

Trip.com Airline Insights on Flights from Cleveland to Greenville

Which airline offers the cheapest direct flights from Cleveland to Greenville?

Data is based on the average price of all nonstop flights from Cleveland to Greenville on Trip.com over the past 12 months.

Based on Trip.com’s data from the past 12 months, Delta Air Lines provides the lowest-priced direct flights from Cleveland to Greenville, with fares starting at US$142.

US$142
US$319
US$495
US$671
Delta Air Lines
US$142
Delta Air Lines
United Airlines
US$320
United Airlines
American Airlines
US$671
American Airlines

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Note: Prices shown on this page are the estimated lowest prices found in the last 24 hours and include all taxes and fees.

Book with no extra fees

Prices displayed on this page are all-inclusive (incl. taxes, fuel surcharges, Civil Aviation Development Fund, etc.), and all fees are clearly shown before you pay. Charges for checked baggage, onboard meals, Wi‑Fi, and other optional services are also included where applicable in the flight cards.

Real-time pricing updates

Prices, availability, and travel details on this page have been updated within the last 24 hours, and for many routes are refreshed in real time. The more popular the route, the more accurate and up-to-date the data.

Change & Cancellation Policy

Trip.com shows the change and cancellation rules for each ticket during the booking process, including all related fees and conditions. Please refer to the following scenarios:
Voluntary cancellation/change:
To request a change or cancellation, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and flight segment, and submit your request. Please note that additional charges may apply based on the airline’s fare rules.
Cancellation/change due to a flight schedule change:
If your flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For full details of change and cancellation policies, please refer to the customer support pages.