US$268️ Cheap Flights from Panama City to San Francisco (2024)

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Panama City to San Francisco - Flights Starting at US$268

Book one-way or return flights from Panama City to San Francisco from as little as US$268. Choose from the popular airlines below and book your flight today!

One way
Round-trip

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

We've found these cheap flights for you. You may book a one-way or round trip as per your needs.

We monitor flight fares to help you seize the best deals effortlessly

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Cheapest airlines flights from Panama City to San Francisco

View airlines operating flights from Panama City to San Francisco. Compare prices, find the option that best suits your travel needs, and enjoy a comfortable journey with a trusted airline.

Avianca

From US$209

Delta Air Lines

From US$302

Copa Airlines

From US$319

American Airlines

From US$332

United Airlines

From US$649

Air Canada

From US$1,031

ANA airlines

Find more flights and airlines

Alternative Routes from Panama City to San Francisco

Discover different routes, airlines, and transfers and find the best alternative flights for your journey from Panama City to San Francisco.

Cheapest
PTY
21:40
17h 5m
2 transfer
SFO
12:45
Tocumen International Airport - San Francisco International Airport
Wed, May 22Avianca
US$209
PTY
21:40
17h 5m
2 transfer
SFO
12:45
Tocumen International Airport - San Francisco International Airport
Wed, May 22Avianca
US$209
Find More Flights

Frequently Asked Questions

When are flight tickets from Panama City (PTY) to San Francisco (SFO) the cheapest?
Airlines adjust prices for flights from Panama City to San Francisco based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.
How much do flights from Panama City (PTY) to San Francisco (SFO) cost?
According to Trip.com's data, the lowest price is around $586.
How long does it take to fly from Panama City (PTY) to San Francisco (SFO) and what is the distance?
It takes around 7 hours 34 minutes to fly from Panama City (PTY) to San Francisco (SFO).
What is the transportation method from the main airport to downtown in San Francisco?
- The distance from San Francisco International Airport to downtown is about 17km. It takes about 30 minutes by taxi.
What are the most popular airlines that fly from Panama City (PTY) to San Francisco (SFO)?
Airlines with flights from Panama City (PTY) to San Francisco (SFO): Copa Airlines and United Airlines.

How to find a cheap flight from Panama City to San Francisco

Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Panama City to San Francisco. Book your flights at the right time and save more.

Book Early

Once prices are gone, they're gone. Lock in deals while you can!

Compare Flight Prices

Compare prices on travel agency and airline websites.

Look Out for Deals

Check airline and travel agency websites for latest flight deals

Check One-way Fares

Buying two cheap one-way flights can sometimes be a better deal than a round-trip.

Try Different Dates

Flying during the week, early in the morning, or late at night can help save money.

Use the Trip.com App

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Panama City to San Francisco Flight Information

Cheapest nonstop flight price	$268
Cheapest round-trip ticket price	$522
Off-season for travel	December
Peak season for travel	October
Flight distance	5,341.28km
Average flight time	7 hours 34 minutes
Popular airline	Avianca