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Flights from Sao Paulo to Sao Tome Island

Search cheap flights from Sao Paulo to Sao Tome Island in the next 3 months. Based on Trip.com's latest 7-day data, one-way fares start at US$847, and round-trip tickets start at US$1,967.

      • VCP 17:15
        21h 30m
        1 stop
        TMS 17:45
        Sao Paulo - Sao Tome Island | Fri, Jun 12 | Azul Airlines
        TMS 19:40
        24h 10m
        1 stop
        VCP 16:50
        Sao Tome Island - Sao Paulo | Sat, Jun 20 | TAP Air Portugal
        US$1,967 US$2,813
        30% off
        30% off
        US$2,813 US$1,967
      • VCP 21:10
        41h 35m
        1 stop
        TMS 17:45
        Sao Paulo - Sao Tome Island | Sat, Jun 13 | Azul Airlines
        TMS 19:40
        24h 10m
        1 stop
        VCP 16:50
        Sao Tome Island - Sao Paulo | Sat, Jun 20 | TAP Air Portugal
        US$1,967 US$2,813
        30% off
        30% off
        US$2,813 US$1,967
      • VCP 17:15
        21h 30m
        1 stop
        TMS 17:45
        Sao Paulo - Sao Tome Island | Tue, Jun 9 | Azul Airlines
        TMS 21:35
        21h 35m
        1 stop
        VCP 16:10
        Sao Tome Island - Sao Paulo | Tue, Jun 16 | TAP Air Portugal
        US$1,996 US$2,813
        28% off
        28% off
        US$2,813 US$1,996
      • VCP 21:10
        41h 35m
        1 stop
        TMS 17:45
        Sao Paulo - Sao Tome Island | Sat, Jun 20 | Azul Airlines
        TMS 21:35
        21h 35m
        1 stop
        VCP 16:10
        Sao Tome Island - Sao Paulo | Tue, Jun 23 | TAP Air Portugal
        US$2,031
        28% off
        US$2,813 US$2,031
      • VCP 18:10
        20h 15m
        1 stop
        TMS 17:25
        Sao Paulo - Sao Tome Island | Mon, Jun 8 | Azul Airlines
        TMS 21:35
        21h 35m
        1 stop
        VCP 16:10
        Sao Tome Island - Sao Paulo | Tue, Jun 16 | TAP Air Portugal
        US$2,069
        26% off
        US$2,813 US$2,069
      • GRU 17:40
        20h 45m
        1 stop
        TMS 17:25
        Sao Paulo - Sao Tome Island | Mon, Jun 8 | LATAM Airlines
        TMS 21:35
        28h 40m
        1 stop
        GRU 23:15
        Sao Tome Island - Sao Paulo | Tue, Jun 16 | TAP Air Portugal
        US$2,098
        25% off
        US$2,813 US$2,098
      • GRU 15:30
        23h 15m
        1 stop
        TMS 17:45
        Sao Paulo - Sao Tome Island | Tue, Jun 16 | TAP Air Portugal
        TMS 19:40
        26h 5m
        1 stop
        GRU 18:45
        Sao Tome Island - Sao Paulo | Mon, Jun 22 | TAP Air Portugal
        US$2,141
        24% off
        US$2,813 US$2,141
      • GRU 00:45
        37h 40m
        1 stop
        TMS 17:25
        Sao Paulo - Sao Tome Island | Mon, Jun 8 | TAP Air Portugal
        TMS 21:35
        28h 40m
        1 stop
        GRU 23:15
        Sao Tome Island - Sao Paulo | Tue, Jun 16 | TAP Air Portugal
        US$2,148
        24% off
        US$2,813 US$2,148
      • GRU 20:45
        42h
        1 stop
        TMS 17:45
        Sao Paulo - Sao Tome Island | Sat, Jun 20 | TAP Air Portugal
        TMS 21:35
        24h
        1 stop
        GRU 18:35
        Sao Tome Island - Sao Paulo | Tue, Jun 23 | TAP Air Portugal
        US$2,194
        22% off
        US$2,813 US$2,194
      • GRU 15:30
        23h 15m
        1 stop
        TMS 17:45
        Sao Paulo - Sao Tome Island | Tue, Jun 9 | TAP Air Portugal
        TMS 21:35
        28h 40m
        1 stop
        GRU 23:15
        Sao Tome Island - Sao Paulo | Tue, Jun 16 | TAP Air Portugal
        US$2,222
        21% off
        US$2,813 US$2,222
      • SAO 13:00
        17h 25m
        1 stop
        TMS 14:00
        Sao Paulo - Sao Tome Island | Tue, May 19 | Normal Airline
        TMS 15:00
        6h
        Nonstop
        SAO 16:00
        Sao Tome Island - Sao Paulo | Thu, May 21 | Normal Airline
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      • VCP 17:15
        21h 30m
        1 stop
        TMS 17:45
        Sao Paulo - Sao Tome Island | Tue, May 26 | Azul Airlines
        US$847 US$1,650
        49% off
        49% off
        US$1,650 US$847
      • GRU 18:05
        15h 5m
        1 stop
        TMS 12:10
        Sao Paulo - Sao Tome Island | Wed, May 20 | Angola Airlines
        US$935 US$1,650
        43% off
        43% off
        US$1,650 US$935
      • GRU 15:30
        23h 15m
        1 stop
        TMS 17:45
        Sao Paulo - Sao Tome Island | Tue, May 26 | TAP Air Portugal
        US$1,001 US$1,650
        39% off
        39% off
        US$1,650 US$1,001
      • VCP 21:20
        41h 25m
        1 stop
        TMS 17:45
        Sao Paulo - Sao Tome Island | Thu, Jun 4 | Azul Airlines
        US$1,006
        39% off
        US$1,650 US$1,006
      • GRU 15:30
        22h 55m
        1 stop
        TMS 17:25
        Sao Paulo - Sao Tome Island | Mon, May 18 | TAP Air Portugal
        US$1,052
        36% off
        US$1,650 US$1,052
      • GRU 15:30
        23h 15m
        1 stop
        TMS 17:45
        Sao Paulo - Sao Tome Island | Tue, Jun 16 | TAP Air Portugal
        US$1,231
        25% off
        US$1,650 US$1,231
      • GRU 15:30
        23h 15m
        1 stop
        TMS 17:45
        Sao Paulo - Sao Tome Island | Sun, Jun 14 | TAP Air Portugal
        US$1,256
        24% off
        US$1,650 US$1,256
      • GRU 00:45
        38h
        1 stop
        TMS 17:45
        Sao Paulo - Sao Tome Island | Sun, Jun 28 | TAP Air Portugal
        US$1,260
        24% off
        US$1,650 US$1,260
      • GRU 15:30
        23h 15m
        1 stop
        TMS 17:45
        Sao Paulo - Sao Tome Island | Fri, Jun 19 | TAP Air Portugal
        US$1,265
        23% off
        US$1,650 US$1,265
      • VCP 18:10
        20h 15m
        1 stop
        TMS 17:25
        Sao Paulo - Sao Tome Island | Mon, May 18 | Azul Airlines
        US$1,303
        21% off
        US$1,650 US$1,303
      • SAO 13:00
        17h 25m
        1 stop
        TMS 14:00
        Sao Paulo - Sao Tome Island | Tue, May 19 | Normal Airline
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        Find more flights

Displayed flight fares from Sao Paulo to Sao Tome Island are based on average prices across airlines for the next 3 months, according to the latest Trip.com database.

Frequently Asked Questions

  • What are the cheapest flights from Sao Paulo to Sao Tome Island (SAO-TMS)?

    Based on Trip.com data, Azul Airlines offers one-way fares as low as US$847 on Cheapest nonstop routes (e.g. VCP to TMS on Tue, May 26), while Azul Airlines offers Cheapest nonstop round-trips from US$1,967 departing on Fri, Jun 12 and returning on Sat, Jun 20.
  • By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Sao Paulo to Sao Tome Island is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.
  • To find best deals on flights from Sao Paulo to Sao Tome Island, you can use various tools on Trip.com:
    · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Tue, May 26, with one-way flights priced at just US$847.
    · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is Azul Airlines.
    · Set up price alerts to easily monitor ticket prices without having to check every day.
    · Check Trip.com flight deals and promo codes frequently.
    · Avoid peak season unless you book very early. It seems the peak season for Sao Tome Island travel is around January.
    · Get exclusive promo codes for Trip.com app users.
  • The cheapest months to fly from Sao Paulo to Sao Tome Island is November, when demand for travel is lower.
  • After crunching the numbers on our May flight calendar, it's currently cheapest to fly from Sao Paulo to Sao Tome Island on May 30, 2026 with TAP Air Portugal, with prices starting at US$2,290.
  • The time difference between Sao Tome Island and Sao Paulo is 3h.
  • Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.

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Note: Prices shown on this page are the estimated lowest prices found in the last 24 hours and include all taxes and fees.

Book with no extra fees

Prices displayed on this page are all-inclusive (incl. taxes, fuel surcharges, Civil Aviation Development Fund, etc.), and all fees are clearly shown before you pay. Charges for checked baggage, onboard meals, Wi‑Fi, and other optional services are also included where applicable in the flight cards.

Real-time pricing updates

Prices, availability, and travel details on this page have been updated within the last 24 hours, and for many routes are refreshed in real time. The more popular the route, the more accurate and up-to-date the data.

Change & Cancellation Policy

Trip.com shows the change and cancellation rules for each ticket during the booking process, including all related fees and conditions. Please refer to the following scenarios:
Voluntary cancellation/change:
To request a change or cancellation, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and flight segment, and submit your request. Please note that additional charges may apply based on the airline’s fare rules.
Cancellation/change due to a flight schedule change:
If your flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For full details of change and cancellation policies, please refer to the customer support pages.