Find American Airlines(AA) flights from Key West to Myrtle Beach

By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Key West to Myrtle Beach is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.

The cheapest months to fly from Key West to Myrtle Beach is October, when demand for travel is lower.

After crunching the numbers on our December flight calendar, it's currently cheapest to fly from Key West to Myrtle Beach on December 13, 2025 with Delta Air Lines, with prices starting at THB 16,570.

The time difference between Myrtle Beach and Key West is 0h.

Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.