Find Copa Airlines(CM) flights from Medellin to Houston

At the moment, you can catch a nonstop flight from Medellin to Houston with the following airlines, including: avianca American Airlines Selected airlines are based on historical data collected from flight bookings users made on Trip.com within the last 90 days.

It takes around 4 hours 59 minutes to fly from Medellin (MDE) to Houston (HOU).

By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Medellin to Houston is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.

The cheapest months to fly from Medellin to Houston is November, when demand for travel is lower.

After crunching the numbers on our December flight calendar, it's currently cheapest to fly from Medellin to Houston on December 16, 2025 with Spirit Airlines, with prices starting at £131.

You can land at any one of the following hubs in Houston, with Jose Maria Cordova International Airport to George Bush Intercontinental Airport (MDE-IAH) is by far the most common option on this route: George Bush Intercontinental Airport (IAH) William P. Hobby Airport (HOU).

The time difference between Houston and Medellin is 1h.

Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.